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Q81II1 (ARCA_BACCR) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 63. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Arginine deiminase
Short name=ADI
EC=3.5.3.6
Alternative name(s):
Arginine dihydrolase
Short name=AD
Gene names
Name:arcA
Ordered Locus Names:BC_0406
OrganismBacillus cereus (strain ATCC 14579 / DSM 31) [Reference proteome] [HAMAP]
Taxonomic identifier226900 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacilli › Bacillales › Bacillaceae › Bacillus › Bacillus cereus group ›

Protein attributes

Sequence length410 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

L-arginine + H2O = L-citrulline + NH3. HAMAP-Rule MF_00242

Pathway

Amino-acid degradation; L-arginine degradation via ADI pathway; carbamoyl phosphate from L-arginine: step 1/2. HAMAP-Rule MF_00242

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the arginine deiminase family.

Ontologies

Keywords
   Biological processArginine metabolism
   Cellular componentCytoplasm
   Molecular functionHydrolase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processarginine catabolic process to ornithine

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionarginine deiminase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 410410Arginine deiminase HAMAP-Rule MF_00242
PRO_0000182199

Sites

Active site4001Amidino-cysteine intermediate By similarity

Sequences

Sequence LengthMass (Da)Tools
Q81II1 [UniParc].

Last modified June 1, 2003. Version 1.
Checksum: 3D3AE8489168BD73

FASTA41046,880
        10         20         30         40         50         60 
MKHPIHVTSE IGELQTVLLK RPGKEVENLT PDYLQQLLFD DIPYLPIIQK EHDYFAQTLR 

        70         80         90        100        110        120 
NRGVEVLYLE KLAAEALVDK KLREEFVDRI LKEGQADVNV AHQTLKEYLL SFSNEELIQK 

       130        140        150        160        170        180 
IMGGVRKNEI ETSKKTHLYE LMEDHYPFYL DPMPNLYFTR DPAASVGDGL TINKMREPAR 

       190        200        210        220        230        240 
RRESLFMEYI IKYHPRFAKH NVPIWLDRDY KFPIEGGDEL ILNEETIAIG VSARTSAKAI 

       250        260        270        280        290        300 
ERLAKNLFSR QNKIKKVLAI EIPKCRAFMH LDTVFTMVDY DKFTIHPAIQ GPKGNMNIYI 

       310        320        330        340        350        360 
LEKGSDEETL KITHRTSLME ALKEVLGLSE LVLIPCGGGD VIASAREQWN DGSNTLAIAP 

       370        380        390        400        410 
GVVVTYDRNY VSNTLLREHG IEVIEVLSSE LSRGRGGPRC MSMPIVRKDI

« Hide

References

[1]"Genome sequence of Bacillus cereus and comparative analysis with Bacillus anthracis."
Ivanova N., Sorokin A., Anderson I., Galleron N., Candelon B., Kapatral V., Bhattacharyya A., Reznik G., Mikhailova N., Lapidus A., Chu L., Mazur M., Goltsman E., Larsen N., D'Souza M., Walunas T., Grechkin Y., Pusch G. expand/collapse author list , Haselkorn R., Fonstein M., Ehrlich S.D., Overbeek R., Kyrpides N.C.
Nature 423:87-91(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 14579 / DSM 31.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE016877 Genomic DNA. Translation: AAP07446.1.
RefSeqNP_830245.1. NC_004722.1.

3D structure databases

ProteinModelPortalQ81II1.
ModBaseSearch...

Protein-protein interaction databases

STRING226900.BC0406.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAP07446; AAP07446; BC_0406.
GeneID1202759.
KEGGbce:BC0406.
PATRIC32596438. VBIBacCer54481_0376.

Phylogenomic databases

eggNOGCOG2235.
KOK01478.
OMAEEHDQFA.
ProtClustDBPRK01388.

Enzyme and pathway databases

BioCycBCER226900:GJEU-408-MONOMER.
UniPathwayUPA00254; UER00364.

Family and domain databases

HAMAPMF_00242. Arg_deiminase.
InterProIPR003198. Amidino_trans.
IPR003876. Arg_deiminase.
[Graphical view]
PANTHERPTHR12737:SF9. PTHR12737:SF9. 1 hit.
PfamPF02274. Amidinotransf. 1 hit.
[Graphical view]
PIRSFPIRSF006356. Arg_deiminase. 1 hit.
PRINTSPR01466. ARGDEIMINASE.
TIGRFAMsTIGR01078. arcA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameARCA_BACCR
AccessionPrimary (citable) accession number: Q81II1
Entry history
Integrated into UniProtKB/Swiss-Prot: March 1, 2005
Last sequence update: June 1, 2003
Last modified: May 1, 2013
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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