Reviewed, UniProtKB/Swiss-Prot Q81FQ3 (AROC1_BACCR)

Names and origin

Protein names

Recommended name:
    Chorismate synthase 1
    EC=4.2.3.5
Alternative name(s):
    5-enolpyruvylshikimate-3-phosphate phospholyase 1

Gene names

Name:	aroC1
Ordered Locus Names:	BC_1516

Organism

Bacillus cereus (strain ATCC 14579 / DSM 31) [Complete proteome] [HAMAP]

Taxonomic identifier

226900 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus › Bacillus cereus group

Protein attributes

Sequence length	390 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate. HAMAP MF_00300
Cofactor	Reduced flavin By similarity.
Pathway	Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 7/7. HAMAP MF_00300
Subunit structure	Homotetramer By similarity.
Sequence similarities	Belongs to the chorismate synthase family.

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis
Molecular function	Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	aromatic amino acid family biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	chorismate synthase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 390	390	Chorismate synthase 1 HAMAP MF_00300		PRO_0000140543

Sequences

	Sequence		Length	Mass (Da)
	Q81FQ3-1 [UniParc]. Last modified June 1, 2003. Version 1. Checksum: A7A137E2961F3CF6	FASTA	390	42,413
	10 20 30 40 50 60 MRYITAGESH GPQLTTIIEG VPAGLSLVAD DINEELARRQ KGYGRGRRMQ IETDQVQILS 70 80 90 100 110 120 GVRHGETLGS PIALVVENRD FAHWTKIMGA EPLTEQEEKE MKRKVTKPRP GHADLNGAIK 130 140 150 160 170 180 YGHRDMRNVL ERSSARETTV RVAAGAVAKK VLAELGIKVA GHVIEIGGVQ AKEITYSSIE 190 200 210 220 230 240 ELKSITEASP VRCLDDEAGN QMMKAIDDAK ANGDSIGGIV EVIVEGMPIG VGSYVHYDRK 250 260 270 280 290 300 LDAKLAAAIM SINAFKGVEI GIGFEAAHRP GSEVHDEILW NEEHGYTRRT NNAGGLEGGM 310 320 330 340 350 360 TTGMPIVVRG VMKPIPTLYK PLQSVDIDTK EPFTASIERS DSCAVPAASV VAEAVVAWEL 370 380 390 ATALIEQFGL DRMELIRENI EKHNEYARGF

References

[1]

"Genome sequence of Bacillus cereus and comparative analysis with Bacillus anthracis." Ivanova N., Sorokin A., Anderson I., Galleron N., Candelon B., Kapatral V., Bhattacharyya A., Reznik G., Mikhailova N., Lapidus A., Chu L., Mazur M., Goltsman E., Larsen N., D'Souza M., Walunas T., Grechkin Y., Pusch G. , Haselkorn R., Fonstein M., Ehrlich S.D., Overbeek R., Kyrpides N.C. Nature 423:87-91(2003) [PubMed: 12721630] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE016877 Genomic DNA. Translation: AAP08496.1.
RefSeq	NP_831295.1.
3D structure databases
HSSP	HSSP built from PDB template 1Q1L based on UniProtKB O66493.
ModBase	Search...
Protein-protein interaction databases
STRING	Q81FQ3.
Genome annotation databases
GeneID	1203865.
GenomeReviews	Gene locus BC_1516 in contig AE016877_GR.
KEGG	bce:BC1516.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q81FQ3.
OMA	PPGLGSH.
Enzyme and pathway databases
BioCyc	BCER226900:BC_1516-MON.
Family and domain databases
HAMAP	MF_00300. [Tree]
InterPro	IPR000453. Chorismate_synth. IPR020541. Chorismate_synthase_CS. [Graphical view]
PANTHER	PTHR21085. Chorismate_synth. 1 hit.
Pfam	PF01264. Chorismate_synt. 1 hit. [Graphical view]
PIRSF	PIRSF001456. Chorismate_synth. 1 hit.
ProDom	PD002941. Chorismate_synth. 1 hit. [Graphical view] [Entries sharing at least one domain]
TIGRFAMs	TIGR00033. aroC. 1 hit.
PROSITE	PS00787. CHORISMATE_SYNTHASE_1. 1 hit. PS00788. CHORISMATE_SYNTHASE_2. 1 hit. PS00789. CHORISMATE_SYNTHASE_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

AROC1_BACCR

Accession

Primary (citable) accession number: Q81FQ3

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 7, 2005
Last sequence update:	June 1, 2003
Last modified:	November 3, 2009
This is version 39 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)