Q81F30 (Q81F30_BACCR) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Peptide methionine sulfoxide reductase MsrA HAMAP MF_01401
Short name=Protein-methionine-S-oxide reductase HAMAP MF_01401
EC=1.8.4.11 HAMAP MF_01401

Alternative name(s):
Peptide-methionine (S)-S-oxide reductase HAMAP MF_01401

Gene names

Name:	msrA HAMAP MF_01401
Ordered Locus Names:	BC_1774

Organism

Bacillus cereus (strain ATCC 14579 / DSM 31) EMBL AAP08750.1

Taxonomic identifier

226900 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus › Bacillus cereus group

Protein attributes

Sequence length	178 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine By similarity. HAMAP MF_01401
Catalytic activity	L-methionine + thioredoxin disulfide + H2O = L-methionine (S)-S-oxide + thioredoxin. HAMAP MF_01401 Peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (S)-S-oxide + thioredoxin. HAMAP MF_01401
Sequence similarities	Belongs to the MsrA Met sulfoxide reductase family. HAMAP MF_01401

Ontologies

Keywords
Molecular function	Oxidoreductase HAMAP MF_01401 EMBL AAP08750.1
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	protein modification process Inferred from electronic annotation. Source: HAMAP
Molecular function	peptide-methionine-(S)-S-oxide reductase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	15	1	By similarity HAMAP MF_01401

Sequences

	Sequence		Length	Mass (Da)
	Q81F30 [UniParc]. Last modified June 1, 2003. Version 1. Checksum: DDC89BFD98548F64	FASTA	178	20,476
	10 20 30 40 50 60 MSEKTYELAT FAGGCFWCMV KPFDELPGIH KVLSGYAGGH VENPTYEQVK AGTSGHLEVV 70 80 90 100 110 120 QITFDPSIFP YQKLLDLYWP QIDPTDDGGQ FFDRGPSYRT AIFYHNETQK GLAEKSKQAL 130 140 150 160 170 AESGMFKDPI VTEIRPAAPF YEAEEYHQHF YKKNPEKYAT EQKESGREDF IKENWQKK

References

[1]

"Genome sequence of Bacillus cereus and comparative analysis with Bacillus anthracis." Ivanova N., Sorokin A., Anderson I., Galleron N., Candelon B., Kapatral V., Bhattacharyya A., Reznik G., Mikhailova N., Lapidus A., Chu L., Mazur M., Goltsman E., Larsen N., D'Souza M., Walunas T., Grechkin Y., Pusch G. , Haselkorn R., Fonstein M., Ehrlich S.D., Overbeek R., Kyrpides N.C. Nature 423:87-91(2003) [PubMed: 12721630] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 14579 / DSM 31.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE016877 Genomic DNA. Translation: AAP08750.1.
RefSeq	NP_831549.1. NC_004722.1.
3D structure databases
HSSP	HSSP built from PDB template 1FF3 based on UniProtKB P27110.
ProteinModelPortal	Q81F30.
ModBase	Search...
Protein-protein interaction databases
STRING	Q81F30.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBBACT00000032986; EBBACP00000032192; EBBACG00000032977.
GeneID	1204123.
GenomeReviews	Gene locus BC_1774 in contig AE016877_GR.
KEGG	bce:BC1774.
PATRIC	32599311. VBIBacCer54481_1764.
Phylogenomic databases
eggNOG	COG0225.
GeneTree	EBGT00050000000580.
HOGENOM	HBG748152.
OMA	LVELYWT.
PhylomeDB	Q81F30.
ProtClustDB	CLSK916383.
Family and domain databases
HAMAP	MF_01401. MsrA. [Tree]
InterPro	IPR002569. Peptide_Met_Sox_Rdtase_MsrA. [Graphical view]
Gene3D	G3DSA:3.30.1060.10. MsrA. 1 hit.
KO	K07304.
Pfam	PF01625. PMSR. 1 hit. [Graphical view]
SUPFAM	SSF55068. MsrA. 1 hit.
TIGRFAMs	TIGR00401. MsrA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q81F30_BACCR

Accession

Primary (citable) accession number: Q81F30

Entry history

Integrated into UniProtKB/TrEMBL:	June 1, 2003
Last sequence update:	June 1, 2003
Last modified:	December 14, 2011
This is version 63 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)