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Q81C42 (AROC2_BACCR) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 55. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Chorismate synthase 2
EC=4.2.3.5
Alternative name(s):
5-enolpyruvylshikimate-3-phosphate phospholyase 2
Gene names
Name:aroC2
Ordered Locus Names:BC_2941
OrganismBacillus cereus (strain ATCC 14579 / DSM 31)
Taxonomic identifier226900 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus › Bacillus cereus group

Protein attributes

Sequence length390 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate. HAMAP MF_00300

Cofactor

Reduced flavin By similarity. HAMAP MF_00300

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 7/7. HAMAP MF_00300

Subunit structure

Homotetramer By similarity. HAMAP MF_00300

Sequence similarities

Belongs to the chorismate synthase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis
   Molecular functionLyase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological processaromatic amino acid family biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionchorismate synthase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 390390Chorismate synthase 2 HAMAP MF_00300
PRO_0000140544

Sequences

Sequence LengthMass (Da)Tools
Q81C42 [UniParc].

Last modified June 1, 2003. Version 1.
Checksum: 0D2CD2121C74363D

FASTA39042,404
        10         20         30         40         50         60 
MRYITAGESH GPQLTVILEG VPAGLTLTAE HINKELLRRQ KGHGRGRRMQ IETDTVEIVS 

        70         80         90        100        110        120 
GVRHGMTLGS PITLIVKNDD FKHWTKVMGA EPISEKESKD MKRTITKPRP GHADLNGAIK 

       130        140        150        160        170        180 
YGHRDIRNVL ERSSARETTV RVAAGAVAKQ ILSELGVEIA GHVLEIGGVK AKHISNLSIE 

       190        200        210        220        230        240 
EIQTITENSP VRCLDKEVEQ EMMNAIDNAK SSGDSIGGIV EVIAEGMPIG VGSYVHYDRK 

       250        260        270        280        290        300 
LDAKLAGAIM SINAFKGAEI GVGFEAARQP GSKVHDEILW DEEKGYTRRT NNAGGLEGGM 

       310        320        330        340        350        360 
TTGMPIIVRG VMKPIPTLYK PLASVDIDTK EAFQASIERS DSCAVPAAGV VAESVVAWEL 

       370        380        390 
ADALVEQFGK DRMELLKQNI MQHNNYAKEF

« Hide

References

[1]"Genome sequence of Bacillus cereus and comparative analysis with Bacillus anthracis."
Ivanova N., Sorokin A., Anderson I., Galleron N., Candelon B., Kapatral V., Bhattacharyya A., Reznik G., Mikhailova N., Lapidus A., Chu L., Mazur M., Goltsman E., Larsen N., D'Souza M., Walunas T., Grechkin Y., Pusch G. expand/collapse author list , Haselkorn R., Fonstein M., Ehrlich S.D., Overbeek R., Kyrpides N.C.
Nature 423:87-91(2003) [PubMed: 12721630] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 14579 / DSM 31.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE016877 Genomic DNA. Translation: AAP09889.1.
RefSeqNP_832688.1. NC_004722.1.

3D structure databases

ProteinModelPortalQ81C42.
SMRQ81C42. Positions 1-390.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ81C42.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBBACT00000032252; EBBACP00000031458; EBBACG00000032243.
GeneID1205289.
GenomeReviewsGene locus BC_2941 in contig AE016877_GR.
KEGGbce:BC2941.
PATRIC32601823. VBIBacCer54481_3016.

Phylogenomic databases

eggNOGCOG0082.
GeneTreeEBGT00050000002373.
HOGENOMHBG292336.
OMAIQTITEN.
PhylomeDBQ81C42.
ProtClustDBPRK12463.

Enzyme and pathway databases

BioCycBCER226900:BC_2941-MONOMER.

Family and domain databases

HAMAPMF_00300. Chorismate_synth.
[Tree]
InterProIPR000453. Chorismate_synth.
IPR020541. Chorismate_synthase_CS.
[Graphical view]
KOK01736.
PANTHERPTHR21085. Chorismate_synth. 1 hit.
PfamPF01264. Chorismate_synt. 1 hit.
[Graphical view]
PIRSFPIRSF001456. Chorismate_synth. 1 hit.
SUPFAMSSF103263. Chorismate_synth. 1 hit.
TIGRFAMsTIGR00033. AroC. 1 hit.
PROSITEPS00787. CHORISMATE_SYNTHASE_1. 1 hit.
PS00788. CHORISMATE_SYNTHASE_2. 1 hit.
PS00789. CHORISMATE_SYNTHASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameAROC2_BACCR
AccessionPrimary (citable) accession number: Q81C42
Entry history
Integrated into UniProtKB/Swiss-Prot: June 7, 2005
Last sequence update: June 1, 2003
Last modified: January 25, 2012
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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