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Protein

Probable malate:quinone oxidoreductase

Gene

mqo

Organism
Bacillus cereus (strain ATCC 14579 / DSM 31 / JCM 2152 / NBRC 15305 / NCIMB 9373 / NRRL B-3711)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

(S)-malate + a quinone = oxaloacetate + reduced quinone.UniRule annotation

Cofactori

FADUniRule annotation

Pathwayi: tricarboxylic acid cycle

This protein is involved in step 1 of the subpathway that synthesizes oxaloacetate from (S)-malate (quinone route).UniRule annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Probable malate:quinone oxidoreductase (mqo)
This subpathway is part of the pathway tricarboxylic acid cycle, which is itself part of Carbohydrate metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes oxaloacetate from (S)-malate (quinone route), the pathway tricarboxylic acid cycle and in Carbohydrate metabolism.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Tricarboxylic acid cycle

Keywords - Ligandi

FAD, Flavoprotein

Enzyme and pathway databases

BioCyciBCER226900:GJEU-2958-MONOMER.
UniPathwayiUPA00223; UER01008.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable malate:quinone oxidoreductaseUniRule annotation (EC:1.1.5.4UniRule annotation)
Alternative name(s):
MQOUniRule annotation
Malate dehydrogenase [quinone]UniRule annotation
Gene namesi
Name:mqoUniRule annotation
Ordered Locus Names:BC_2959
OrganismiBacillus cereus (strain ATCC 14579 / DSM 31 / JCM 2152 / NBRC 15305 / NCIMB 9373 / NRRL B-3711)
Taxonomic identifieri226900 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillusBacillus cereus group
Proteomesi
  • UP000001417 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 497497Probable malate:quinone oxidoreductasePRO_0000128705Add
BLAST

Proteomic databases

PRIDEiQ81C25.

Interactioni

Protein-protein interaction databases

STRINGi226900.BC2959.

Structurei

3D structure databases

ProteinModelPortaliQ81C25.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the MQO family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0579. LUCA.
KOiK00116.
OMAiEPIAATK.

Family and domain databases

Gene3Di3.50.50.60. 2 hits.
HAMAPiMF_00212. MQO. 1 hit.
InterProiIPR023753. FAD/NAD-binding_dom.
IPR006231. MQO.
[Graphical view]
PfamiPF06039. Mqo. 1 hit.
[Graphical view]
SUPFAMiSSF51905. SSF51905. 1 hit.
TIGRFAMsiTIGR01320. mal_quin_oxido. 1 hit.

Sequencei

Sequence statusi: Complete.

Q81C25-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQQKTDVILI GAGIMSATLG SLLKELAPEW EIKVFEKLAS AGEESSNEWN
60 70 80 90 100
NAGTGHSALC ELNYTSEKAD GSIDISKAVK VNEQFQLSRQ FWAYLVKSKL
110 120 130 140 150
IRNPQDFIMP LPHMSLVQGK KNVEFLKNRF EALSKNPLFQ GMEFSDAPET
160 170 180 190 200
LKKWLPLIME GRTSNEPMAA TKIDSGTDVN FGALTRMLFD YLKTKNVELN
210 220 230 240 250
YKHSVENIKR TKNGLWEVKV HDMNSGKIEH HTAKFVFIGG GGGSLPLLQK
260 270 280 290 300
TGIPESKHIG GFPVSGLFMV CKNQKVVEQH HAKVYGKAKV GAPPMSVPHL
310 320 330 340 350
DTRYIDNKKA LLFGPFAGFS PKFLKTGSNL DLIGSVKPNN VLTMLAAGVK
360 370 380 390 400
EMGLTKYLIQ QVMLSHEKRM LDFPAFIPNA KSEDWDIVVA GQRVQVIKDT
410 420 430 440 450
DAGGKGTLQF GTEVVSAADG SIAALLGASP GASTAVHVML EVLEKCFPSR
460 470 480 490
MIEWEEKIKE MIPSYGISLT ENPRLFQDLH TSTGRTLGLN EKETVHN
Length:497
Mass (Da):54,803
Last modified:June 1, 2003 - v1
Checksum:i18FFF1A1BB16848B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016877 Genomic DNA. Translation: AAP09907.1.
RefSeqiNP_832706.1. NC_004722.1.
WP_011110189.1. NC_004722.1.

Genome annotation databases

EnsemblBacteriaiAAP09907; AAP09907; BC_2959.
GeneIDi1205307.
KEGGibce:BC2959.
PATRICi32601859. VBIBacCer54481_3034.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016877 Genomic DNA. Translation: AAP09907.1.
RefSeqiNP_832706.1. NC_004722.1.
WP_011110189.1. NC_004722.1.

3D structure databases

ProteinModelPortaliQ81C25.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi226900.BC2959.

Proteomic databases

PRIDEiQ81C25.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAP09907; AAP09907; BC_2959.
GeneIDi1205307.
KEGGibce:BC2959.
PATRICi32601859. VBIBacCer54481_3034.

Phylogenomic databases

eggNOGiCOG0579. LUCA.
KOiK00116.
OMAiEPIAATK.

Enzyme and pathway databases

UniPathwayiUPA00223; UER01008.
BioCyciBCER226900:GJEU-2958-MONOMER.

Family and domain databases

Gene3Di3.50.50.60. 2 hits.
HAMAPiMF_00212. MQO. 1 hit.
InterProiIPR023753. FAD/NAD-binding_dom.
IPR006231. MQO.
[Graphical view]
PfamiPF06039. Mqo. 1 hit.
[Graphical view]
SUPFAMiSSF51905. SSF51905. 1 hit.
TIGRFAMsiTIGR01320. mal_quin_oxido. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiMQO_BACCR
AccessioniPrimary (citable) accession number: Q81C25
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 15, 2003
Last sequence update: June 1, 2003
Last modified: September 7, 2016
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.