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Protein

Cell division protein FtsZ

Gene

ftsZ

Organism
Bacillus cereus (strain ATCC 14579 / DSM 31 / JCM 2152 / NBRC 15305 / NCIMB 9373 / NRRL B-3711)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei139GTPUniRule annotation1
Binding sitei143GTPUniRule annotation1
Binding sitei187GTPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi21 – 25GTPUniRule annotation5
Nucleotide bindingi108 – 110GTPUniRule annotation3

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processCell cycle, Cell division, SeptationUniRule annotation
LigandGTP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Cell division protein FtsZUniRule annotation
Gene namesi
Name:ftsZUniRule annotation
Ordered Locus Names:BC_3906Imported
OrganismiBacillus cereus (strain ATCC 14579 / DSM 31 / JCM 2152 / NBRC 15305 / NCIMB 9373 / NRRL B-3711)Imported
Taxonomic identifieri226900 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillusBacillus cereus group
Proteomesi
  • UP000001417 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

PTM / Processingi

Proteomic databases

PRIDEiQ819Q7

Interactioni

Protein-protein interaction databases

STRINGi226900.BC3906

Structurei

3D structure databases

ProteinModelPortaliQ819Q7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini13 – 205TubulinInterPro annotationAdd BLAST193
Domaini207 – 324Tubulin_CInterPro annotationAdd BLAST118

Sequence similaritiesi

Belongs to the FtsZ family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CDK Bacteria
COG0206 LUCA
KOiK03531
OMAiMRAVKGI

Family and domain databases

CDDicd02201 FtsZ_type1, 1 hit
Gene3Di3.30.1330.20, 1 hit
3.40.50.1440, 1 hit
HAMAPiMF_00909 FtsZ, 1 hit
InterProiView protein in InterPro
IPR000158 Cell_div_FtsZ
IPR020805 Cell_div_FtsZ_CS
IPR024757 FtsZ_C
IPR008280 Tub_FtsZ_C
IPR018316 Tubulin/FtsZ_2-layer-sand-dom
IPR037103 Tubulin/FtsZ_C_sf
IPR036525 Tubulin/FtsZ_GTPase_sf
IPR003008 Tubulin_FtsZ_GTPase
PfamiView protein in Pfam
PF12327 FtsZ_C, 1 hit
PF00091 Tubulin, 1 hit
PRINTSiPR00423 CELLDVISFTSZ
SMARTiView protein in SMART
SM00864 Tubulin, 1 hit
SM00865 Tubulin_C, 1 hit
SUPFAMiSSF52490 SSF52490, 1 hit
SSF55307 SSF55307, 1 hit
TIGRFAMsiTIGR00065 ftsZ, 1 hit
PROSITEiView protein in PROSITE
PS01134 FTSZ_1, 1 hit
PS01135 FTSZ_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q819Q7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLEFDTTQDQ LANIKVIGVG GGGNNAVNRM IEHGVQGVDF IAVNTDAQAL
60 70 80 90 100
NLSKAETKMQ IGGKLTRGLG AGANPEVGKK AAEESKEQIQ EALRGADMVF
110 120 130 140 150
VTAGMGGGTG TGAAPVVAQV AKELGALTVG VVTRPFTFEG RKRATQAASG
160 170 180 190 200
IAAFKENVDT LIVIPNDRLL EIVDKNTPML EAFREADNVL RQGVQGISDL
210 220 230 240 250
IATPGLINLD FADVKTIMSN RGSALMGIGS GNGENRAAEA AKKAISSPLL
260 270 280 290 300
ETSIDGAQGV IMNITGGANL SLYEVQEAAD IVASASDPEV NMIFGSVINE
310 320 330 340 350
GLKDDIVVTV IATGFDDSIA TQPPKPIIRP NANHTQQQQQ PVAQPSKQRE
360 370 380
VKREMKREEP VVHERHSDSD DIDIPAFLRN RRRR
Length:384
Mass (Da):40,679
Last modified:June 1, 2003 - v1
Checksum:i8B11EA86E6044EEC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016877 Genomic DNA Translation: AAP10827.1
RefSeqiNP_833626.1, NC_004722.1
WP_000888984.1, NC_004722.1

Genome annotation databases

EnsemblBacteriaiAAP10827; AAP10827; BC_3906
GeneIDi1206251
31628642
KEGGibce:BC3906
PATRICifig|226900.8.peg.4028

Similar proteinsi

Entry informationi

Entry nameiQ819Q7_BACCR
AccessioniPrimary (citable) accession number: Q819Q7
Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: June 1, 2003
Last modified: March 28, 2018
This is version 113 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health