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Q819L4 (SPEA_BACCR) Reviewed, UniProtKB/Swiss-Prot

Last modified November 13, 2013. Version 71. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Arginine decarboxylase

EC=4.1.1.19
Gene names
Name:speA
Ordered Locus Names:BC_3962
OrganismBacillus cereus (strain ATCC 14579 / DSM 31) [Reference proteome] [HAMAP]
Taxonomic identifier226900 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillusBacillus cereus group

Protein attributes

Sequence length460 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the formation of agmatine from arginine By similarity.

Catalytic activity

L-arginine = agmatine + CO2.

Cofactor

Pyridoxal phosphate By similarity.

Pathway

Amine and polyamine biosynthesis; agmatine biosynthesis; agmatine from L-arginine: step 1/1.

Subcellular location

Cytoplasm Probable.

Sequence similarities

Belongs to the Orn/Lys/Arg decarboxylase class-I family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 460460Arginine decarboxylase
PRO_0000201145

Amino acid modifications

Modified residue2261N6-(pyridoxal phosphate)lysine By similarity

Sequences

Sequence LengthMass (Da)Tools
Q819L4 [UniParc].

Last modified June 1, 2003. Version 1.
Checksum: 92EB8987F823C839

FASTA46050,324
        10         20         30         40         50         60 
MSQYETPLFT ALVEHSKRNP IQFHIPGHKK GQGMDPTFRE FIGHNALAID LINIAPLDDL 

        70         80         90        100        110        120 
HHPKGMIKEA QDLAAAAFGA DHTFFSIQGT SGAIMTMVMS VCGPGDKILV PRNVHKSVMS 

       130        140        150        160        170        180 
AIIFSGAKPI FMHPEIDPKL GISHGITIQS VKKALEEHSD AKGLLVINPT YFGFAADLEQ 

       190        200        210        220        230        240 
IVQLAHSYDI PVLVDEAHGV HIHFHDELPM SAMQAGADMA ATSVHKLGGS LTQSSILNVK 

       250        260        270        280        290        300 
EGLVNVKHVQ SIISMLTTTS TSYILLASLD VARKRLATEG TALIEQTIQL AEHVRDAINS 

       310        320        330        340        350        360 
IEHLYCPGKE MLGTDATFNY DPTKIIVSVK DLGITGHQAE VWLREQYNIE VELSDLYNIL 

       370        380        390        400        410        420 
CLITLGDTES DTNTLIAALQ DLAATFRNRA DKGVQVQVEI PEIPVLALSP RDAFYSETEV 

       430        440        450        460 
IPFENAAGRI IADFVMVYPP GIPIFTPGGN YYTRKLRVYS 

« Hide

References

[1]"Genome sequence of Bacillus cereus and comparative analysis with Bacillus anthracis."
Ivanova N., Sorokin A., Anderson I., Galleron N., Candelon B., Kapatral V., Bhattacharyya A., Reznik G., Mikhailova N., Lapidus A., Chu L., Mazur M., Goltsman E., Larsen N., D'Souza M., Walunas T., Grechkin Y., Pusch G. expand/collapse author list , Haselkorn R., Fonstein M., Ehrlich S.D., Overbeek R., Kyrpides N.C.
Nature 423:87-91(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 14579 / DSM 31.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE016877 Genomic DNA. Translation: AAP10882.1.
RefSeqNP_833681.1. NC_004722.1.

3D structure databases

ProteinModelPortalQ819L4.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING226900.BC3962.

Proteomic databases

PRIDEQ819L4.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAP10882; AAP10882; BC_3962.
GeneID1206307.
KEGGbce:BC3962.
PATRIC32603966. VBIBacCer54481_4086.

Phylogenomic databases

eggNOGCOG1982.
KOK01585.
OMAMYNILCL.
OrthoDBEOG61CKX5.
ProtClustDBCLSK873379.

Enzyme and pathway databases

BioCycBCER226900:GJEU-3958-MONOMER.
UniPathwayUPA00186; UER00284.

Family and domain databases

Gene3D3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProIPR000310. Orn/Lys/Arg_deCO2ase_major_dom.
IPR008286. Prn/Lys/Arg_de-COase_C.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PfamPF01276. OKR_DC_1. 1 hit.
PF03711. OKR_DC_1_C. 1 hit.
[Graphical view]
SUPFAMSSF53383. SSF53383. 1 hit.
PROSITEPS00703. OKR_DC_1. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSPEA_BACCR
AccessionPrimary (citable) accession number: Q819L4
Entry history
Integrated into UniProtKB/Swiss-Prot: March 15, 2004
Last sequence update: June 1, 2003
Last modified: November 13, 2013
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways