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Q818W1 (ARGB_BACCR) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 63. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Acetylglutamate kinase

EC=2.7.2.8
Alternative name(s):
N-acetyl-L-glutamate 5-phosphotransferase
NAG kinase
Short name=AGK
Gene names
Name:argB
Ordered Locus Names:BC_4128
OrganismBacillus cereus (strain ATCC 14579 / DSM 31)
Taxonomic identifier226900 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacillalesBacillaceaeBacillusBacillus cereus group

Protein attributes

Sequence length255 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + N-acetyl-L-glutamate = ADP + N-acetyl-L-glutamate 5-phosphate. HAMAP MF_00082_B

Pathway

Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 2/4. HAMAP MF_00082_B

Subcellular location

Cytoplasm By similarity HAMAP MF_00082_B.

Sequence similarities

Belongs to the acetylglutamate kinase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Arginine biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological processarginine biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

acetylglutamate kinase activity

Inferred from electronic annotation. Source: EC

carbamate kinase activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 255255Acetylglutamate kinase HAMAP MF_00082_B
PRO_0000112579

Regions

Region40 – 412Substrate binding By similarity

Sites

Binding site621Substrate By similarity
Binding site1531Substrate By similarity
Site81Transition state stabilizer By similarity
Site2121Transition state stabilizer By similarity

Sequences

Sequence LengthMass (Da)Tools
Q818W1 [UniParc].

Last modified June 1, 2003. Version 1.
Checksum: E346C85AA10B7D45

FASTA25527,174
        10         20         30         40         50         60 
MSDYIVVKCG GSMLNQLNDV FFECIKKLQQ KYKVVIVHGG GPEIDAKLKD CNINVEKRDG 

        70         80         90        100        110        120 
LRITPKEVMD VVQMVLCGST NKKLVMNLQK HNLLAVGCSG CDGNLLQIQP VSEEIGYVGE 

       130        140        150        160        170        180 
VSYVETALLK GLINMEYIPV IAPIGVNGNE IYNINADNAA AGIAAALGAK ELVFITDVDG 

       190        200        210        220        230        240 
ILHEGNLVKE TDESEIATFI ETGVITGGMI PKVQAALASL KMGVQKISIV NGTKDFTEVT 

       250 
GECIGTTVTK GVSIA 

« Hide

References

[1]"Genome sequence of Bacillus cereus and comparative analysis with Bacillus anthracis."
Ivanova N., Sorokin A., Anderson I., Galleron N., Candelon B., Kapatral V., Bhattacharyya A., Reznik G., Mikhailova N., Lapidus A., Chu L., Mazur M., Goltsman E., Larsen N., D'Souza M., Walunas T., Grechkin Y., Pusch G. expand/collapse author list , Haselkorn R., Fonstein M., Ehrlich S.D., Overbeek R., Kyrpides N.C.
Nature 423:87-91(2003) [PubMed: 12721630] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 14579 / DSM 31.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE016877 Genomic DNA. Translation: AAP11046.1.
RefSeqNP_833845.1. NC_004722.1.

3D structure databases

ProteinModelPortalQ818W1.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ818W1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBBACT00000033881; EBBACP00000033087; EBBACG00000033872.
GeneID1206473.
GenomeReviewsGene locus BC_4128 in contig AE016877_GR.
KEGGbce:BC4128.
PATRIC32604326. VBIBacCer54481_4266.

Phylogenomic databases

eggNOGCOG0548.
GeneTreeEBGT00050000001971.
HOGENOMHBG497643.
OMACNINVEK.
PhylomeDBQ818W1.
ProtClustDBPRK00942.

Enzyme and pathway databases

BioCycBCER226900:BC_4128-MONOMER.

Family and domain databases

HAMAPMF_00082_B. ArgB_B.
[Tree]
InterProIPR004662. AcgluKinase.
IPR001048. Asp/Glu/Uridylate_kinase.
IPR003964. Bac_carb_kinase.
[Graphical view]
Gene3DG3DSA:3.40.1160.10. Aa_kinase. 1 hit.
KOK00930.
PfamPF00696. AA_kinase. 1 hit.
[Graphical view]
PIRSFPIRSF000728. NAGK. 1 hit.
PRINTSPR01469. CARBMTKINASE.
SUPFAMSSF53633. Aa_kinase. 1 hit.
TIGRFAMsTIGR00761. ArgB. 1 hit.
ProtoNetSearch...

Entry information

Entry nameARGB_BACCR
AccessionPrimary (citable) accession number: Q818W1
Entry history
Integrated into UniProtKB/Swiss-Prot: November 7, 2003
Last sequence update: June 1, 2003
Last modified: January 25, 2012
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families