Reviewed,
UniProtKB/Swiss-Prot Q818W1 (ARGB_BACCR)
Last modified
November 3, 2009.
Version 45.
History...
Clusters with 100%,
90%,
50% identity |
Documents (2) |
Third-party data |
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Names and origin
| Protein names | Recommended name: Acetylglutamate kinase EC=2.7.2.8 Alternative name(s): NAG kinase Short name=AGK N-acetyl-L-glutamate 5-phosphotransferase | ||||
| Gene names |
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| Organism | Bacillus cereus (strain ATCC 14579 / DSM 31) [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 226900 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus › Bacillus cereus group |
Protein attributes
| Sequence length | 255 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Catalytic activity | ATP + N-acetyl-L-glutamate = ADP + N-acetyl-L-glutamate 5-phosphate. HAMAP MF_00082 |
| Pathway | Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 2/4. HAMAP MF_00082 |
| Subcellular location | Cytoplasm Probable. |
| Sequence similarities | Belongs to the acetylglutamate kinase family. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Amino-acid biosynthesis Arginine biosynthesis |
| Cellular component | Cytoplasm |
| Ligand | ATP-binding Nucleotide-binding |
| Molecular function | Kinase Transferase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | arginine biosynthetic process Inferred from electronic annotation. Source: HAMAP |
| Cellular component | cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular function | ATP binding Inferred from electronic annotation. Source: HAMAP acetylglutamate kinase activityInferred from electronic annotation. Source: HAMAP carbamate kinase activityInferred from electronic annotation. Source: InterPro |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 255 | 255 | Acetylglutamate kinase HAMAP MF_00082 | PRO_0000112579 | |||||
Regions | |||||||||
| Region | 40 – 41 | 2 | Substrate binding By similarity | ||||||
Sites | |||||||||
| Binding site | 62 | 1 | Substrate By similarity | ||||||
| Binding site | 153 | 1 | Substrate By similarity | ||||||
| Site | 8 | 1 | Transition state stabilizer By similarity | ||||||
| Site | 212 | 1 | Transition state stabilizer By similarity | ||||||
Sequences
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References
| [1] | "Genome sequence of Bacillus cereus and comparative analysis with Bacillus anthracis." Ivanova N., Sorokin A., Anderson I., Galleron N., Candelon B., Kapatral V., Bhattacharyya A., Reznik G., Mikhailova N., Lapidus A., Chu L., Mazur M., Goltsman E., Larsen N., D'Souza M., Walunas T., Grechkin Y., Pusch G. Kyrpides N.C.Nature 423:87-91(2003) [PubMed: 12721630] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. |
Cross-references
Sequence databases | |
|---|---|
| AE016877 Genomic DNA. Translation: AAP11046.1. | |
| RefSeq | NP_833845.1. |
3D structure databases | |
| HSSP | HSSP built from PDB template 1GS5 based on UniProtKB P11445. |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | Q818W1. |
Genome annotation databases | |
| GeneID | 1206473. |
| GenomeReviews | Gene locus BC_4128 in contig AE016877_GR. |
| KEGG | bce:BC4128. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| HOGENOM | Q818W1. |
| OMA | MVLCGST. |
Enzyme and pathway databases | |
| BioCyc | BCER226900:BC_4128-MON. |
Family and domain databases | |
| HAMAP | MF_00082. [Tree] |
| InterPro | IPR004662. AcgluKinase. IPR001048. Asp/Glu/Uridylate_kinase. IPR003964. Bac_carb_kinase. IPR011148. GlcNAc_kinase. [Graphical view] |
| Gene3D | G3DSA:3.40.1160.10. Aa_kinase. 1 hit. |
| Pfam | PF00696. AA_kinase. 1 hit. [Graphical view] |
| PIRSF | PIRSF000728. NAGK. 1 hit. |
| PRINTS | PR01469. CARBMTKINASE. |
| TIGRFAMs | TIGR00761. argB. 1 hit. |
| ProtoNet | Search... |
Entry information
| Entry name | ARGB_BACCR | ||||||||
| Accession | Primary (citable) accession number: Q818W1 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes) | ||||||||
Relevant documents
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

Clusters with


