Reviewed,
UniProtKB/Swiss-Prot Q814T6 (MURA2_BACCR)
Last modified
November 3, 2009.
Version 38.
History...
Clusters with 100%,
90%,
50% identity |
Documents (2) |
Third-party data |
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Names and origin
| Protein names | Recommended name: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 2 EC=2.5.1.7 Alternative name(s): Enoylpyruvate transferase 2 UDP-N-acetylglucosamine enolpyruvyl transferase 2 Short name=EPT 2 | ||||
| Gene names |
| ||||
| Organism | Bacillus cereus (strain ATCC 14579 / DSM 31) [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 226900 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus › Bacillus cereus group |
Protein attributes
| Sequence length | 429 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Function | Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine By similarity. |
| Catalytic activity | Phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine = phosphate + UDP-N-acetyl-3-O-(1-carboxyvinyl)-D-glucosamine. HAMAP MF_00111 |
| Pathway | Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP MF_00111 |
| Subcellular location | Cytoplasm Probable. |
| Sequence similarities | Belongs to the EPSP synthase family. MurA subfamily. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Cell cycle Cell division Cell shape Cell wall biogenesis/degradation Peptidoglycan synthesis |
| Cellular component | Cytoplasm |
| Molecular function | Transferase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | UDP-N-acetylgalactosamine biosynthetic process Inferred from electronic annotation. Source: InterPro cell cycleInferred from electronic annotation. Source: UniProtKB-KW cell divisionInferred from electronic annotation. Source: UniProtKB-KW cell wall organizationInferred from electronic annotation. Source: UniProtKB-KW peptidoglycan biosynthetic processInferred from electronic annotation. Source: HAMAP regulation of cell shapeInferred from electronic annotation. Source: UniProtKB-KW |
| Cellular component | cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular function | UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity Inferred from electronic annotation. Source: HAMAP |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 429 | 429 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase 2 HAMAP MF_00111 | PRO_0000231156 | |||||
Sites | |||||||||
| Active site | 117 | 1 | Proton donor By similarity | ||||||
| Binding site | 117 | 1 | Phosphoenolpyruvate (covalent) By similarity | ||||||
Sequences
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References
| [1] | "Genome sequence of Bacillus cereus and comparative analysis with Bacillus anthracis." Ivanova N., Sorokin A., Anderson I., Galleron N., Candelon B., Kapatral V., Bhattacharyya A., Reznik G., Mikhailova N., Lapidus A., Chu L., Mazur M., Goltsman E., Larsen N., D'Souza M., Walunas T., Grechkin Y., Pusch G. Kyrpides N.C.Nature 423:87-91(2003) [PubMed: 12721630] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. |
Cross-references
Sequence databases | |
|---|---|
| AE016877 Genomic DNA. Translation: AAP12197.1. | |
| RefSeq | NP_834996.1. |
3D structure databases | |
| HSSP | HSSP built from PDB template 1DLG based on UniProtKB P33038. |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | Q814T6. |
Genome annotation databases | |
| GeneID | 1207674. |
| GenomeReviews | Gene locus BC_5334 in contig AE016877_GR. |
| KEGG | bce:BC5334. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| HOGENOM | Q814T6. |
| OMA | DNVIPTH. |
Enzyme and pathway databases | |
| BioCyc | BCER226900:BC_5334-MON. |
Family and domain databases | |
| HAMAP | MF_00111. [Tree] |
| InterPro | IPR001986. EPSP_synthase_core. IPR005750. UDP_GlcNAc_COvinyl_MurA. [Graphical view] |
| Gene3D | G3DSA:3.65.10.10. EPSP_synthase. 2 hits. |
| PANTHER | PTHR21090:SF4. AcGlu_Tran_MurA. 1 hit. |
| Pfam | PF00275. EPSP_synthase. 1 hit. [Graphical view] |
| ProDom | PD001867. EPSP_synth. 1 hit. [Graphical view] [Entries sharing at least one domain] |
| TIGRFAMs | TIGR01072. murA. 1 hit. |
| ProtoNet | Search... |
Entry information
| Entry name | MURA2_BACCR | ||||||||
| Accession | Primary (citable) accession number: Q814T6 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes) | ||||||||
Relevant documents
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

Clusters with


