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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Bacillus cereus (strain ATCC 14579 / DSM 31 / JCM 2152 / NBRC 15305 / NCIMB 9373 / NRRL B-3711)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:BC_5364
OrganismiBacillus cereus (strain ATCC 14579 / DSM 31 / JCM 2152 / NBRC 15305 / NCIMB 9373 / NRRL B-3711)
Taxonomic identifieri226900 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillusBacillus cereus group
Proteomesi
  • UP000001417 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001515271 – 556Arginine--tRNA ligaseAdd BLAST556

Proteomic databases

PRIDEiQ814Q8

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi226900.BC5364

Structurei

3D structure databases

ProteinModelPortaliQ814Q8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi132 – 142"HIGH" regionAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0018 LUCA
KOiK01887
OMAiHGMSTRQ

Family and domain databases

CDDicd00671 ArgRS_core, 1 hit
Gene3Di3.30.1360.70, 1 hit
3.40.50.620, 1 hit
HAMAPiMF_00123 Arg_tRNA_synth, 1 hit
InterProiView protein in InterPro
IPR001412 aa-tRNA-synth_I_CS
IPR001278 Arg-tRNA-ligase
IPR005148 Arg-tRNA-synth_N
IPR036695 Arg-tRNA-synth_N_sf
IPR035684 ArgRS_core
IPR008909 DALR_anticod-bd
IPR014729 Rossmann-like_a/b/a_fold
IPR009080 tRNAsynth_Ia_anticodon-bd
PANTHERiPTHR11956 PTHR11956, 1 hit
PfamiView protein in Pfam
PF03485 Arg_tRNA_synt_N, 1 hit
PF05746 DALR_1, 1 hit
PF00750 tRNA-synt_1d, 1 hit
PRINTSiPR01038 TRNASYNTHARG
SMARTiView protein in SMART
SM01016 Arg_tRNA_synt_N, 1 hit
SM00836 DALR_1, 1 hit
SUPFAMiSSF47323 SSF47323, 1 hit
SSF55190 SSF55190, 1 hit
TIGRFAMsiTIGR00456 argS, 1 hit
PROSITEiView protein in PROSITE
PS00178 AA_TRNA_LIGASE_I, 1 hit

Sequencei

Sequence statusi: Complete.

Q814Q8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNSLEQVKGL IKEEIQAAVL KAELATEEQI PNVVLESPKD KTNGDFSTNM
60 70 80 90 100
AMQLARVAKK APRMIAEELV ANFDKAKASI EKIEIAGPGF INFYMDNSYL
110 120 130 140 150
TDLIPTIVNA GEAYGETNTG KGEKVQVEFV SANPTGDLHL GHARGAAVGD
160 170 180 190 200
TLCNLLAKAG YDVSREYYIN DAGNQIHNLA LSVEARYMQA LGLEKEMPED
210 220 230 240 250
GYHGADIIGI GKRLAEEFGD RYAKADEKES YEFYREYGLK YELAKLQKDL
260 270 280 290 300
ESFRVKFDVW FSETSLYKNG KIDQALAVLK ERDEIFEEDG ATWFRSMTYG
310 320 330 340 350
DDKNRVLIKN DGSYTYLTPD IAYHRDKLER GFDKLINIWG ADHHGYIPRM
360 370 380 390 400
KAAIQALGYD KETLEVEIIQ MVQLYQNGEK MKMSKRTGKA VTLRELMEEV
410 420 430 440 450
GVDAMRYFFA MRSGDSHLDF DMDLAVSKSN ENPVYYAQYA HARVCSILRQ
460 470 480 490 500
GEELGLATGG DVNYKLVTSE KEVELLKKLG EFPAVVADAA QKRLPHRITN
510 520 530 540 550
YAFELAATLH SFYNAEKVLN QDNLELSKAR YELMKAVRTT LQNALAIVGV

SAPEKM
Length:556
Mass (Da):62,502
Last modified:June 1, 2003 - v1
Checksum:i8ACC27EB1AD2F5D2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016877 Genomic DNA Translation: AAP12226.1
RefSeqiNP_835025.1, NC_004722.1
WP_001086456.1, NC_004722.1

Genome annotation databases

EnsemblBacteriaiAAP12226; AAP12226; BC_5364
GeneIDi1207704
KEGGibce:BC5364
PATRICifig|226900.8.peg.5540

Similar proteinsi

Entry informationi

Entry nameiSYR_BACCR
AccessioniPrimary (citable) accession number: Q814Q8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 14, 2003
Last sequence update: June 1, 2003
Last modified: March 28, 2018
This is version 93 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health