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Q814Q2 (SPEB_BACCR) Reviewed, UniProtKB/Swiss-Prot

Last modified November 13, 2013. Version 73. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Agmatinase

EC=3.5.3.11
Alternative name(s):
Agmatine ureohydrolase
Short name=AUH
Gene names
Name:speB
Ordered Locus Names:BC_5370
OrganismBacillus cereus (strain ATCC 14579 / DSM 31) [Reference proteome] [HAMAP]
Taxonomic identifier226900 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillusBacillus cereus group

Protein attributes

Sequence length290 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the formation of putrescine from agmatine By similarity.

Catalytic activity

Agmatine + H2O = putrescine + urea.

Cofactor

Manganese By similarity.

Pathway

Amine and polyamine biosynthesis; putrescine biosynthesis via agmatine pathway; putrescine from agmatine: step 1/1.

Sequence similarities

Belongs to the arginase family. Agmatinase subfamily.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 290290Agmatinase
PRO_0000173726

Sites

Metal binding1121Manganese By similarity
Metal binding1351Manganese By similarity
Metal binding1371Manganese By similarity
Metal binding1391Manganese By similarity
Metal binding2161Manganese By similarity
Metal binding2181Manganese By similarity

Sequences

Sequence LengthMass (Da)Tools
Q814Q2 [UniParc].

Last modified June 1, 2003. Version 1.
Checksum: D538E9EBDE734B5B

FASTA29032,389
        10         20         30         40         50         60 
MRFDEAYSGK VFIKSHPSFE ESKVVIYGMP MDWTVSYRPG SRFGPARIRE VSIGLEEYSP 

        70         80         90        100        110        120 
YLDRELEEVK YFDAGDIPLP FGNAQRSLDM IEEYVSKLLD ADKFPLGLGG EHLVSWPIFK 

       130        140        150        160        170        180 
AMAKKYPDLA IIHMDAHTDL RESYEGEPLS HSTPIRKVCD LIGPENVYSF GIRSGMKEEF 

       190        200        210        220        230        240 
EWAKEVGMNL YKFDVLEPLK EVLPKLAGRP VYVTIDIDVL DPAHAPGTGT LEAGGITSKE 

       250        260        270        280        290 
LLDSIVAIAN SNINVVGADL VEVAPVYDHS DQTPVAASKF VREMLLGWVK 

« Hide

References

[1]"Genome sequence of Bacillus cereus and comparative analysis with Bacillus anthracis."
Ivanova N., Sorokin A., Anderson I., Galleron N., Candelon B., Kapatral V., Bhattacharyya A., Reznik G., Mikhailova N., Lapidus A., Chu L., Mazur M., Goltsman E., Larsen N., D'Souza M., Walunas T., Grechkin Y., Pusch G. expand/collapse author list , Haselkorn R., Fonstein M., Ehrlich S.D., Overbeek R., Kyrpides N.C.
Nature 423:87-91(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 14579 / DSM 31.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE016877 Genomic DNA. Translation: AAP12232.1.
RefSeqNP_835031.1. NC_004722.1.

3D structure databases

ProteinModelPortalQ814Q2.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING226900.BC5370.

Proteomic databases

PRIDEQ814Q2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAP12232; AAP12232; BC_5370.
GeneID1207710.
KEGGbce:BC5370.
PATRIC32606948. VBIBacCer54481_5545.

Phylogenomic databases

eggNOGCOG0010.
KOK01480.
OMAKPDYSLY.
OrthoDBEOG6R2GW5.
ProtClustDBCLSK888062.

Enzyme and pathway databases

BioCycBCER226900:GJEU-5362-MONOMER.
UniPathwayUPA00534; UER00287.

Family and domain databases

Gene3D3.40.800.10. 1 hit.
InterProIPR005925. Agmatinase-rel.
IPR006035. Ureohydrolase.
IPR023696. Ureohydrolase_domain.
IPR020855. Ureohydrolase_Mn_BS.
[Graphical view]
PANTHERPTHR11358. PTHR11358. 1 hit.
PfamPF00491. Arginase. 1 hit.
[Graphical view]
PIRSFPIRSF036979. Arginase. 1 hit.
TIGRFAMsTIGR01230. agmatinase. 1 hit.
PROSITEPS01053. ARGINASE_1. 1 hit.
PS51409. ARGINASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSPEB_BACCR
AccessionPrimary (citable) accession number: Q814Q2
Entry history
Integrated into UniProtKB/Swiss-Prot: March 15, 2004
Last sequence update: June 1, 2003
Last modified: November 13, 2013
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways