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Q814Q2

- SPEB_BACCR

UniProt

Q814Q2 - SPEB_BACCR

Protein

Agmatinase

Gene

speB

Organism
Bacillus cereus (strain ATCC 14579 / DSM 31)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 75 (01 Oct 2014)
      Sequence version 1 (01 Jun 2003)
      Previous versions | rss
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    Functioni

    Catalyzes the formation of putrescine from agmatine.By similarity

    Catalytic activityi

    Agmatine + H2O = putrescine + urea.

    Cofactori

    Manganese.PROSITE-ProRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi112 – 1121ManganesePROSITE-ProRule annotation
    Metal bindingi135 – 1351ManganesePROSITE-ProRule annotation
    Metal bindingi137 – 1371ManganesePROSITE-ProRule annotation
    Metal bindingi139 – 1391ManganesePROSITE-ProRule annotation
    Metal bindingi216 – 2161ManganesePROSITE-ProRule annotation
    Metal bindingi218 – 2181ManganesePROSITE-ProRule annotation

    GO - Molecular functioni

    1. agmatinase activity Source: UniProtKB-EC
    2. metal ion binding Source: UniProtKB-KW

    GO - Biological processi

    1. putrescine biosynthetic process from arginine Source: UniProtKB-UniPathway
    2. spermidine biosynthetic process Source: UniProtKB-KW

    Keywords - Molecular functioni

    Hydrolase

    Keywords - Biological processi

    Polyamine biosynthesis, Putrescine biosynthesis, Spermidine biosynthesis

    Keywords - Ligandi

    Manganese, Metal-binding

    Enzyme and pathway databases

    BioCyciBCER226900:GJEU-5362-MONOMER.
    UniPathwayiUPA00534; UER00287.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Agmatinase (EC:3.5.3.11)
    Alternative name(s):
    Agmatine ureohydrolase
    Short name:
    AUH
    Gene namesi
    Name:speB
    Ordered Locus Names:BC_5370
    OrganismiBacillus cereus (strain ATCC 14579 / DSM 31)
    Taxonomic identifieri226900 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillusBacillus cereus group
    ProteomesiUP000001417: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 290290AgmatinasePRO_0000173726Add
    BLAST

    Proteomic databases

    PRIDEiQ814Q2.

    Interactioni

    Protein-protein interaction databases

    STRINGi226900.BC5370.

    Structurei

    3D structure databases

    ProteinModelPortaliQ814Q2.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the arginase family. Agmatinase subfamily.PROSITE-ProRule annotation

    Phylogenomic databases

    eggNOGiCOG0010.
    KOiK01480.
    OMAiSPPYDPF.
    OrthoDBiEOG6R2GW5.

    Family and domain databases

    Gene3Di3.40.800.10. 1 hit.
    InterProiIPR005925. Agmatinase-rel.
    IPR006035. Ureohydrolase.
    IPR023696. Ureohydrolase_domain.
    IPR020855. Ureohydrolase_Mn_BS.
    [Graphical view]
    PANTHERiPTHR11358. PTHR11358. 1 hit.
    PfamiPF00491. Arginase. 1 hit.
    [Graphical view]
    PIRSFiPIRSF036979. Arginase. 1 hit.
    TIGRFAMsiTIGR01230. agmatinase. 1 hit.
    PROSITEiPS01053. ARGINASE_1. 1 hit.
    PS51409. ARGINASE_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q814Q2-1 [UniParc]FASTAAdd to Basket

    « Hide

    MRFDEAYSGK VFIKSHPSFE ESKVVIYGMP MDWTVSYRPG SRFGPARIRE    50
    VSIGLEEYSP YLDRELEEVK YFDAGDIPLP FGNAQRSLDM IEEYVSKLLD 100
    ADKFPLGLGG EHLVSWPIFK AMAKKYPDLA IIHMDAHTDL RESYEGEPLS 150
    HSTPIRKVCD LIGPENVYSF GIRSGMKEEF EWAKEVGMNL YKFDVLEPLK 200
    EVLPKLAGRP VYVTIDIDVL DPAHAPGTGT LEAGGITSKE LLDSIVAIAN 250
    SNINVVGADL VEVAPVYDHS DQTPVAASKF VREMLLGWVK 290
    Length:290
    Mass (Da):32,389
    Last modified:June 1, 2003 - v1
    Checksum:iD538E9EBDE734B5B
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE016877 Genomic DNA. Translation: AAP12232.1.
    RefSeqiNP_835031.1. NC_004722.1.

    Genome annotation databases

    EnsemblBacteriaiAAP12232; AAP12232; BC_5370.
    GeneIDi1207710.
    KEGGibce:BC5370.
    PATRICi32606948. VBIBacCer54481_5545.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE016877 Genomic DNA. Translation: AAP12232.1 .
    RefSeqi NP_835031.1. NC_004722.1.

    3D structure databases

    ProteinModelPortali Q814Q2.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 226900.BC5370.

    Proteomic databases

    PRIDEi Q814Q2.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAP12232 ; AAP12232 ; BC_5370 .
    GeneIDi 1207710.
    KEGGi bce:BC5370.
    PATRICi 32606948. VBIBacCer54481_5545.

    Phylogenomic databases

    eggNOGi COG0010.
    KOi K01480.
    OMAi SPPYDPF.
    OrthoDBi EOG6R2GW5.

    Enzyme and pathway databases

    UniPathwayi UPA00534 ; UER00287 .
    BioCyci BCER226900:GJEU-5362-MONOMER.

    Family and domain databases

    Gene3Di 3.40.800.10. 1 hit.
    InterProi IPR005925. Agmatinase-rel.
    IPR006035. Ureohydrolase.
    IPR023696. Ureohydrolase_domain.
    IPR020855. Ureohydrolase_Mn_BS.
    [Graphical view ]
    PANTHERi PTHR11358. PTHR11358. 1 hit.
    Pfami PF00491. Arginase. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF036979. Arginase. 1 hit.
    TIGRFAMsi TIGR01230. agmatinase. 1 hit.
    PROSITEi PS01053. ARGINASE_1. 1 hit.
    PS51409. ARGINASE_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 14579 / DSM 31.

    Entry informationi

    Entry nameiSPEB_BACCR
    AccessioniPrimary (citable) accession number: Q814Q2
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: March 15, 2004
    Last sequence update: June 1, 2003
    Last modified: October 1, 2014
    This is version 75 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3