Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q812B9 (Q812B9_RAT) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 59. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein names
Gene names
Name:Pten EMBL AAO31949.1 RGD 61995
OrganismRattus norvegicus (Rat) EMBL AAO31949.1
Taxonomic identifier10116 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

Protein attributes

Sequence length121 AA.
Sequence statusFragment.
Protein existenceEvidence at transcript level

Ontologies

Gene Ontology (GO)
   Biological_processactivation of mitotic anaphase-promoting complex activity

Inferred from electronic annotation. Source: Ensembl

aging

Inferred from expression pattern PubMed 18054565. Source: RGD

angiogenesis

Inferred from electronic annotation. Source: Ensembl

canonical Wnt signaling pathway

Inferred from electronic annotation. Source: Ensembl

cardiac muscle tissue development

Inferred from electronic annotation. Source: Ensembl

central nervous system myelin maintenance

Inferred from electronic annotation. Source: Ensembl

central nervous system neuron axonogenesis

Inferred from electronic annotation. Source: Ensembl

dendritic spine morphogenesis

Inferred from electronic annotation. Source: Ensembl

dentate gyrus development

Inferred from electronic annotation. Source: Ensembl

endothelial cell migration

Inferred from electronic annotation. Source: Ensembl

forebrain morphogenesis

Inferred from electronic annotation. Source: Ensembl

inositol phosphate dephosphorylation

Inferred from electronic annotation. Source: Ensembl

locomotor rhythm

Inferred from electronic annotation. Source: Ensembl

long term synaptic depression

Inferred from mutant phenotype PubMed 20628354. Source: RGD

long-term synaptic potentiation

Inferred from electronic annotation. Source: Ensembl

male mating behavior

Inferred from electronic annotation. Source: Ensembl

maternal behavior

Inferred from electronic annotation. Source: Ensembl

memory

Inferred from mutant phenotype PubMed 15317872. Source: RGD

multicellular organismal response to stress

Inferred from electronic annotation. Source: Ensembl

negative regulation of apoptotic process

Inferred from electronic annotation. Source: Ensembl

negative regulation of axonogenesis

Inferred from electronic annotation. Source: Ensembl

negative regulation of cell aging

Inferred from electronic annotation. Source: Ensembl

negative regulation of cell migration

Inferred from electronic annotation. Source: Ensembl

negative regulation of cell proliferation

Inferred from direct assay PubMed 14656929. Source: RGD

negative regulation of cell size

Inferred from electronic annotation. Source: Ensembl

negative regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle

Inferred from electronic annotation. Source: Ensembl

negative regulation of dendritic spine morphogenesis

Inferred from electronic annotation. Source: Ensembl

negative regulation of epithelial cell proliferation

Inferred from electronic annotation. Source: Ensembl

negative regulation of excitatory postsynaptic membrane potential

Inferred from electronic annotation. Source: Ensembl

negative regulation of focal adhesion assembly

Inferred from electronic annotation. Source: Ensembl

negative regulation of myelination

Inferred from electronic annotation. Source: Ensembl

negative regulation of organ growth

Inferred from electronic annotation. Source: Ensembl

negative regulation of phagocytosis

Inferred from mutant phenotype PubMed 18056380. Source: RGD

negative regulation of protein kinase B signaling

Inferred from electronic annotation. Source: Ensembl

negative regulation of ribosome biogenesis

Inferred from electronic annotation. Source: Ensembl

negative regulation of synaptic vesicle clustering

Inferred from electronic annotation. Source: Ensembl

neuron projection development

Inferred from direct assay PubMed 14990793. Source: RGD

neuron-neuron synaptic transmission

Inferred from electronic annotation. Source: Ensembl

phosphatidylinositol dephosphorylation

Inferred from mutant phenotype PubMed 20628354. Source: RGD

platelet-derived growth factor receptor signaling pathway

Inferred from direct assay PubMed 14718524. Source: RGD

positive regulation of apoptotic process

Inferred from mutant phenotype PubMed 16502258. Source: RGD

positive regulation of apoptotic signaling pathway

Inferred from electronic annotation. Source: Ensembl

positive regulation of cell proliferation

Inferred from electronic annotation. Source: Ensembl

positive regulation of excitatory postsynaptic membrane potential

Inferred from electronic annotation. Source: Ensembl

positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Inferred from electronic annotation. Source: Ensembl

positive regulation of sequence-specific DNA binding transcription factor activity

Inferred from electronic annotation. Source: Ensembl

postsynaptic density assembly

Inferred from electronic annotation. Source: Ensembl

prepulse inhibition

Inferred from electronic annotation. Source: Ensembl

presynaptic membrane assembly

Inferred from electronic annotation. Source: Ensembl

prostate gland growth

Inferred from electronic annotation. Source: Ensembl

protein kinase B signaling

Inferred from electronic annotation. Source: Ensembl

protein stabilization

Inferred from electronic annotation. Source: Ensembl

regulation of B cell apoptotic process

Inferred from electronic annotation. Source: Ensembl

regulation of myeloid cell apoptotic process

Inferred from electronic annotation. Source: Ensembl

response to ATP

Inferred from expression pattern PubMed 17132626. Source: RGD

response to arsenic-containing substance

Inferred from expression pattern PubMed 14713550. Source: RGD

response to drug

Inferred from expression pattern PubMed 16188065. Source: RGD

response to estradiol

Inferred from expression pattern PubMed 15482376. Source: RGD

response to ethanol

Inferred from expression pattern PubMed 12939597. Source: RGD

response to glucose

Inferred from expression pattern PubMed 16804083. Source: RGD

response to inorganic substance

Inferred from expression pattern PubMed 17302912. Source: RGD

response to nutrient

Inferred from expression pattern PubMed 17166883. Source: RGD

response to organic cyclic compound

Inferred from expression pattern PubMed 18095365. Source: RGD

response to organic substance

Inferred from expression pattern PubMed 16807353. Source: RGD

response to zinc ion

Inferred from expression pattern PubMed 18054565. Source: RGD

rhythmic synaptic transmission

Inferred from electronic annotation. Source: Ensembl

social behavior

Inferred from electronic annotation. Source: Ensembl

synapse maturation

Inferred from electronic annotation. Source: Ensembl

   Cellular_componentSchmidt-Lanterman incisure

Inferred from electronic annotation. Source: Ensembl

cytoplasm

Inferred from direct assay PubMed 17239858. Source: RGD

cytoplasmic side of plasma membrane

Inferred from electronic annotation. Source: Ensembl

dendritic spine

Inferred from direct assay PubMed 20628354. Source: RGD

mitochondrion

Inferred from direct assay PubMed 16502258. Source: RGD

myelin sheath adaxonal region

Inferred from electronic annotation. Source: Ensembl

neuron projection

Inferred from direct assay PubMed 20628354. Source: RGD

nucleus

Inferred from direct assay PubMed 17239858. Source: RGD

postsynaptic membrane

Inferred from direct assay PubMed 20628354. Source: RGD

   Molecular_functionPDZ domain binding

Inferred from physical interaction PubMed 20628354. Source: RGD

inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity

Inferred from electronic annotation. Source: Ensembl

phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity

Inferred from direct assay PubMed 18056380. Source: RGD

phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity

Inferred from electronic annotation. Source: Ensembl

phosphatidylinositol-3-phosphatase activity

Inferred from electronic annotation. Source: Ensembl

platelet-derived growth factor receptor binding

Inferred from direct assay PubMed 14718524. Source: RGD

protein serine/threonine phosphatase activity

Inferred from electronic annotation. Source: Ensembl

protein tyrosine phosphatase activity

Inferred from electronic annotation. Source: Ensembl

protein tyrosine/serine/threonine phosphatase activity

Traceable author statement PubMed 14718524. Source: RGD

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Experimental info

Non-terminal residue11 EMBL AAO31949.1
Non-terminal residue1211 EMBL AAO31949.1

Sequences

Sequence LengthMass (Da)Tools
Q812B9 [UniParc].

Last modified June 1, 2003. Version 1.
Checksum: 88F7EF43562BA9DF

FASTA12113,727
        10         20         30         40         50         60 
VNTFFIPGPE ETSEKVENGS LCDQEIDSIC SIERADNDKE YLVLTLTKND LDKANKDKAN 

        70         80         90        100        110        120 
RYFSPNFKVK LYFTKTVEEP SNPEASSSTS VTPDVSDNEP DHYRYSDTTD SDPENEPFDE 


D 

« Hide

References

[1]"Recurrent allelic imbalance at the rat Pten locus in DMBA-induced fibrosarcomas."
Sjoling A., Samuelson E., Adamovic T., Behboudi A., Rohme D., Levan G.
Genes Chromosomes Cancer 36:70-79(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: BN EMBL AAO31949.1.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF455570 Genomic DNA. Translation: AAO31949.1.
UniGeneRn.22158.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

UCSCRGD:61995. rat.

Organism-specific databases

RGD61995. Pten.

Phylogenomic databases

InParanoidQ812B9.

Gene expression databases

ArrayExpressQ812B9.
GenevestigatorQ812B9.

Family and domain databases

InterProIPR000008. C2_dom.
IPR014020. Tensin_C2-dom.
[Graphical view]
PfamPF10409. PTEN_C2. 1 hit.
[Graphical view]
SUPFAMSSF49562. SSF49562. 1 hit.
PROSITEPS51182. C2_TENSIN. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ812B9_RAT
AccessionPrimary (citable) accession number: Q812B9
Entry history
Integrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: June 1, 2003
Last modified: April 16, 2014
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)