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Protein
Submitted name:

Anti-human Fc gamma receptor III 3G8 gamma heavy chain variable region

Gene
N/A
Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Keywords - Molecular functioni

ReceptorImported

Names & Taxonomyi

Protein namesi
Submitted name:
Anti-human Fc gamma receptor III 3G8 gamma heavy chain variable regionImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi22 ↔ 97Combined sources

Proteomic databases

PRIDEiQ811U5.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2IQAX-ray2.00B/H1-118[»]
2R0WX-ray2.50H1-118[»]
3BAEX-ray1.59H2-117[»]
ProteinModelPortaliQ811U5.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ811U5.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini1 – 117117Ig-like (immunoglobulin-like)InterPro annotationAdd
BLAST

Phylogenomic databases

HOVERGENiHBG018013.
PhylomeDBiQ811U5.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
InterProiIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003599. Ig_sub.
IPR013106. Ig_V-set.
[Graphical view]
PfamiPF07686. V-set. 1 hit.
[Graphical view]
SMARTiSM00409. IG. 1 hit.
SM00406. IGv. 1 hit.
[Graphical view]
SUPFAMiSSF48726. SSF48726. 1 hit.
PROSITEiPS50835. IG_LIKE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q811U5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
QVTLKESGPG ILQPSQTLSL TCSFSGFSLR TSGMGVGWIR QPSGKGLEWL
60 70 80 90 100
AHIWWDDDKR YNPALKSRLT ISKDTSSNQV FLKIASVDTA DTATYYCAQI
110
NPAWFAYWGQ GTLVTVSA
Length:118
Mass (Da):12,979
Last modified:June 1, 2003 - v1
Checksum:iF57BB07033742E99
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported
Non-terminal residuei118 – 1181Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY173025 mRNA. Translation: AAO18227.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY173025 mRNA. Translation: AAO18227.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2IQAX-ray2.00B/H1-118[»]
2R0WX-ray2.50H1-118[»]
3BAEX-ray1.59H2-117[»]
ProteinModelPortaliQ811U5.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiQ811U5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

HOVERGENiHBG018013.
PhylomeDBiQ811U5.

Miscellaneous databases

EvolutionaryTraceiQ811U5.
NextBioi35564218.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
InterProiIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003599. Ig_sub.
IPR013106. Ig_V-set.
[Graphical view]
PfamiPF07686. V-set. 1 hit.
[Graphical view]
SMARTiSM00409. IG. 1 hit.
SM00406. IGv. 1 hit.
[Graphical view]
SUPFAMiSSF48726. SSF48726. 1 hit.
PROSITEiPS50835. IG_LIKE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "A recombinant bispecific single-chain Fv antibody against HLA class II and FcgammaRIII (CD16) triggers effective lysis of lymphoma cells."
    Bruenke J., Fischer B., Barbin K., Schreiter K., Wachter Y., Mahr K., Titgemeyer F., Niederweis M., Peipp M., Zunino S.J., Repp R., Valerius T., Fey G.H.
    Br. J. Haematol. 125:167-179(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: BALB/cImported.
  2. Cited for: X-RAY CRYSTALLOGRAPHY (2.00 ANGSTROMS), DISULFIDE BONDS.
  3. "Amyloid-beta-anti-amyloid-beta complex structure reveals an extended conformation in the immunodominant B-cell epitope."
    Miles L.A., Wun K.S., Crespi G.A., Fodero-Tavoletti M.T., Galatis D., Bagley C.J., Beyreuther K., Masters C.L., Cappai R., McKinstry W.J., Barnham K.J., Parker M.W.
    J. Mol. Biol. 377:181-192(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (1.59 ANGSTROMS) OF 2-117, DISULFIDE BONDS.

Entry informationi

Entry nameiQ811U5_MOUSE
AccessioniPrimary (citable) accession number: Q811U5
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: June 1, 2003
Last modified: May 11, 2016
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.