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Q811I1

- Q811I1_MOUSE

UniProt

Q811I1 - Q811I1_MOUSE

Protein
Submitted name:

Desmoglein-2

Gene

Dsg2

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 81 (01 Oct 2014)
      Sequence version 1 (01 Jun 2003)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. calcium ion binding Source: InterPro

    GO - Biological processi

    1. homophilic cell adhesion Source: InterPro

    Keywords - Biological processi

    Cell adhesionSAAS annotation

    Keywords - Ligandi

    CalciumUniRule annotationSAAS annotation

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Desmoglein-2Imported
    Submitted name:
    Dsg2 proteinImported
    Gene namesi
    Name:Dsg2Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 18

    Organism-specific databases

    MGIiMGI:1196466. Dsg2.

    Subcellular locationi

    GO - Cellular componenti

    1. desmosome Source: MGI
    2. integral component of membrane Source: UniProtKB-KW
    3. plasma membrane Source: InterPro

    Keywords - Cellular componenti

    Membrane

    Expressioni

    Gene expression databases

    GenevestigatoriQ811I1.

    Family & Domainsi

    Keywords - Domaini

    RepeatSAAS annotation, Transmembrane, Transmembrane helixSAAS annotation

    Phylogenomic databases

    GeneTreeiENSGT00740000114904.
    HOGENOMiHOG000146465.
    HOVERGENiHBG067346.

    Family and domain databases

    Gene3Di2.60.40.60. 3 hits.
    InterProiIPR002126. Cadherin.
    IPR015919. Cadherin-like.
    IPR020894. Cadherin_CS.
    IPR009122. Desmosomal_cadherin.
    [Graphical view]
    PANTHERiPTHR24025. PTHR24025. 1 hit.
    PfamiPF00028. Cadherin. 2 hits.
    [Graphical view]
    PRINTSiPR00205. CADHERIN.
    SMARTiSM00112. CA. 2 hits.
    [Graphical view]
    SUPFAMiSSF49313. SSF49313. 3 hits.
    PROSITEiPS00232. CADHERIN_1. 2 hits.
    PS50268. CADHERIN_2. 3 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q811I1-1 [UniParc]FASTAAdd to Basket

    « Hide

    MARSPGDRCA LLLLVQLLAV VCLDFGNGLH LEVFSPRNEG KPFPKHTHLV    50
    RQKRAWITAP VALREGEDLS RKNPIAKIHS DLAEEKGIKI TYKYTGKGIT 100
    EPPFGIFVFD RNTGELNITS ILDREETPYF LLTGYALDSR GNNLEKPLEL 150
    RIKVLDINDN EPVFTQEVFV GSIEELSAAH TLVMKITATD ADDPETLNAK 200
    VSYRIVSQEP ANSHMFYLNK DTGEIYTTSF TLDREEHSSY SLTVEARDGN 250
    GQITDKPVQQ AQVQIRILDV NDNIPVVENK MYEGTVEENQ VNVEVMRIKV 300
    TDADEVGSDN WLANFTFASG NEGGYFHIET DTQTNEGIVT LVKVSCKCPP 350
    PGWDCGYRKD 360
    Length:360
    Mass (Da):40,312
    Last modified:June 1, 2003 - v1
    Checksum:i6A758B84705E8245
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC132091 Genomic DNA. No translation available.
    BC044848 mRNA. Translation: AAH44848.1.
    UniGeneiMm.345891.

    Genome annotation databases

    EnsembliENSMUST00000120102; ENSMUSP00000113153; ENSMUSG00000044393.
    UCSCiuc008eer.1. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC132091 Genomic DNA. No translation available.
    BC044848 mRNA. Translation: AAH44848.1 .
    UniGenei Mm.345891.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000120102 ; ENSMUSP00000113153 ; ENSMUSG00000044393 .
    UCSCi uc008eer.1. mouse.

    Organism-specific databases

    MGIi MGI:1196466. Dsg2.

    Phylogenomic databases

    GeneTreei ENSGT00740000114904.
    HOGENOMi HOG000146465.
    HOVERGENi HBG067346.

    Miscellaneous databases

    ChiTaRSi DSG2. mouse.
    NextBioi 13872304.
    SOURCEi Search...

    Gene expression databases

    Genevestigatori Q811I1.

    Family and domain databases

    Gene3Di 2.60.40.60. 3 hits.
    InterProi IPR002126. Cadherin.
    IPR015919. Cadherin-like.
    IPR020894. Cadherin_CS.
    IPR009122. Desmosomal_cadherin.
    [Graphical view ]
    PANTHERi PTHR24025. PTHR24025. 1 hit.
    Pfami PF00028. Cadherin. 2 hits.
    [Graphical view ]
    PRINTSi PR00205. CADHERIN.
    SMARTi SM00112. CA. 2 hits.
    [Graphical view ]
    SUPFAMi SSF49313. SSF49313. 3 hits.
    PROSITEi PS00232. CADHERIN_1. 2 hits.
    PS50268. CADHERIN_2. 3 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
      , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: FVB/NImported.
      Tissue: Mammary tumor. C3Imported.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6JImported.
    3. Ensembl
      Submitted (FEB-2012) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.

    Entry informationi

    Entry nameiQ811I1_MOUSE
    AccessioniPrimary (citable) accession number: Q811I1
    Entry historyi
    Integrated into UniProtKB/TrEMBL: June 1, 2003
    Last sequence update: June 1, 2003
    Last modified: October 1, 2014
    This is version 81 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3