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Protein
Submitted name:

Desmoglein-2

Gene

Dsg2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandCalciumSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Desmoglein-2Imported
Submitted name:
Dsg2 proteinImported
Gene namesi
Name:Dsg2Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 18

Organism-specific databases

MGIiMGI:1196466. Dsg2.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 28Sequence analysisAdd BLAST28
ChainiPRO_501121094229 – 360Sequence analysisAdd BLAST332

Expressioni

Gene expression databases

BgeeiENSMUSG00000044393.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini75 – 162CAInterPro annotationAdd BLAST88
Domaini186 – 275CAInterPro annotationAdd BLAST90

Keywords - Domaini

RepeatSAAS annotation, SignalSequence analysis, Transmembrane, Transmembrane helixSAAS annotation

Phylogenomic databases

eggNOGiKOG3594. Eukaryota.
ENOG410XQHI. LUCA.
GeneTreeiENSGT00760000118906.
HOGENOMiHOG000146465.
HOVERGENiHBG067346.

Family and domain databases

InterProiView protein in InterPro
IPR002126. Cadherin.
IPR015919. Cadherin-like.
IPR020894. Cadherin_CS.
IPR009122. Desmosomal_cadherin.
PANTHERiPTHR24025. PTHR24025. 1 hit.
PfamiView protein in Pfam
PF00028. Cadherin. 2 hits.
PRINTSiPR00205. CADHERIN.
SMARTiView protein in SMART
SM00112. CA. 2 hits.
SUPFAMiSSF49313. SSF49313. 3 hits.
PROSITEiView protein in PROSITE
PS00232. CADHERIN_1. 2 hits.

Sequencei

Sequence statusi: Complete.

Q811I1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MARSPGDRCA LLLLVQLLAV VCLDFGNGLH LEVFSPRNEG KPFPKHTHLV
60 70 80 90 100
RQKRAWITAP VALREGEDLS RKNPIAKIHS DLAEEKGIKI TYKYTGKGIT
110 120 130 140 150
EPPFGIFVFD RNTGELNITS ILDREETPYF LLTGYALDSR GNNLEKPLEL
160 170 180 190 200
RIKVLDINDN EPVFTQEVFV GSIEELSAAH TLVMKITATD ADDPETLNAK
210 220 230 240 250
VSYRIVSQEP ANSHMFYLNK DTGEIYTTSF TLDREEHSSY SLTVEARDGN
260 270 280 290 300
GQITDKPVQQ AQVQIRILDV NDNIPVVENK MYEGTVEENQ VNVEVMRIKV
310 320 330 340 350
TDADEVGSDN WLANFTFASG NEGGYFHIET DTQTNEGIVT LVKVSCKCPP
360
PGWDCGYRKD
Length:360
Mass (Da):40,312
Last modified:June 1, 2003 - v1
Checksum:i6A758B84705E8245
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC132091 Genomic DNA. No translation available.
BC044848 mRNA. Translation: AAH44848.1.
UniGeneiMm.345891.

Genome annotation databases

EnsembliENSMUST00000120102; ENSMUSP00000113153; ENSMUSG00000044393.
UCSCiuc008eer.1. mouse.

Similar proteinsi

Entry informationi

Entry nameiQ811I1_MOUSE
AccessioniPrimary (citable) accession number: Q811I1
Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: June 1, 2003
Last modified: November 22, 2017
This is version 115 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported