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Protein

Zinc finger and BTB domain-containing protein 41

Gene

Zbtb41

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

May be involved in transcriptional regulation.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri208 – 231C2H2-type 1PROSITE-ProRule annotationAdd BLAST24
Zinc fingeri360 – 382C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri388 – 410C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri421 – 444C2H2-type 4PROSITE-ProRule annotationAdd BLAST24
Zinc fingeri462 – 484C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri490 – 513C2H2-type 6PROSITE-ProRule annotationAdd BLAST24
Zinc fingeri517 – 540C2H2-type 7PROSITE-ProRule annotationAdd BLAST24
Zinc fingeri546 – 568C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri574 – 596C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri602 – 624C2H2-type 10PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri630 – 653C2H2-type 11PROSITE-ProRule annotationAdd BLAST24
Zinc fingeri667 – 689C2H2-type 12PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri695 – 717C2H2-type 13PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri723 – 746C2H2-type 14PROSITE-ProRule annotationAdd BLAST24

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Zinc finger and BTB domain-containing protein 41
Gene namesi
Name:Zbtb41
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 1

Organism-specific databases

MGIiMGI:2444487 Zbtb41

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002778151 – 908Zinc finger and BTB domain-containing protein 41Add BLAST908

Proteomic databases

PaxDbiQ811F1
PRIDEiQ811F1

PTM databases

iPTMnetiQ811F1
PhosphoSitePlusiQ811F1

Expressioni

Gene expression databases

BgeeiENSMUSG00000033964
CleanExiMM_ZBTB41
ExpressionAtlasiQ811F1 baseline and differential
GenevisibleiQ811F1 MM

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000045570

Structurei

3D structure databases

ProteinModelPortaliQ811F1
SMRiQ811F1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini89 – 153BTBPROSITE-ProRule annotationAdd BLAST65

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri208 – 231C2H2-type 1PROSITE-ProRule annotationAdd BLAST24
Zinc fingeri360 – 382C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri388 – 410C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri421 – 444C2H2-type 4PROSITE-ProRule annotationAdd BLAST24
Zinc fingeri462 – 484C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri490 – 513C2H2-type 6PROSITE-ProRule annotationAdd BLAST24
Zinc fingeri517 – 540C2H2-type 7PROSITE-ProRule annotationAdd BLAST24
Zinc fingeri546 – 568C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri574 – 596C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri602 – 624C2H2-type 10PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri630 – 653C2H2-type 11PROSITE-ProRule annotationAdd BLAST24
Zinc fingeri667 – 689C2H2-type 12PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri695 – 717C2H2-type 13PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri723 – 746C2H2-type 14PROSITE-ProRule annotationAdd BLAST24

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

eggNOGiKOG1721 Eukaryota
COG5048 LUCA
GeneTreeiENSGT00550000075080
HOGENOMiHOG000054186
HOVERGENiHBG080093
InParanoidiQ811F1
KOiK10513
OMAiGSDNLNQ
OrthoDBiEOG091G02KC
PhylomeDBiQ811F1
TreeFamiTF350933

Family and domain databases

InterProiView protein in InterPro
IPR000210 BTB/POZ_dom
IPR011333 SKP1/BTB/POZ_sf
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
PfamiView protein in Pfam
PF00651 BTB, 1 hit
SMARTiView protein in SMART
SM00225 BTB, 1 hit
SM00355 ZnF_C2H2, 14 hits
SUPFAMiSSF54695 SSF54695, 1 hit
SSF57667 SSF57667, 7 hits
PROSITEiView protein in PROSITE
PS50097 BTB, 1 hit
PS00028 ZINC_FINGER_C2H2_1, 13 hits
PS50157 ZINC_FINGER_C2H2_2, 14 hits

Sequencei

Sequence statusi: Complete.

Q811F1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKKRRKVTSN LDEKIHLGYH KDSSEENAAV ECGQVTYTQA PERPTPEAAQ
60 70 80 90 100
RCQELPPSPD QRKLLSSLQY NKNLLKYLND DRQKQPSFCD LLIIVEGKEF
110 120 130 140 150
SAHKVVVAVG SSYFHACLSK NPSTDVVTLD HVTHSVFQHL LEFLYTSEFF
160 170 180 190 200
VYKYEIPLVL EAAKFLDIID AVKLLNNENV AAFQAELTEK SSPEETLNEL
210 220 230 240 250
TGRLSSSHQC KFCSRHFCYK KSLENHLAKT HRSLLLGKKH GLKMLERSFS
260 270 280 290 300
TRRSKRNRKC PVKFEDTSDD EQESGDGSDN LHQESSEKER SDRNDSEDPG
310 320 330 340 350
SEYNAEDEEL EEEVSDEDSD TEQSDKDNDA EEEPEAGDSA GSIHEGLAPV
360 370 380 390 400
IIQNSNKKIL QCPKCDKTFD RIGKYESHTR VHTGEKPFEC DICHQRYSTK
410 420 430 440 450
SNLTVHRKKH SNEVEFHRKE HKCPYCNKLH ASKKTLAKHV KRFHPENAQE
460 470 480 490 500
FISIKKTKSE SWKCDICKKS FTRRPHLEEH MILHSQDKPF KCTYCEEHFK
510 520 530 540 550
SRFARLKHQE KFHLGPFPCD ICGRQFNDTG NLKRHIECTH GGKRKWTCFI
560 570 580 590 600
CGKSVRERTT LKEHLRIHSG EKPHLCSICG QSFRHGSSYR LHLRVHHDDK
610 620 630 640 650
RYECDECGKT FIRHDHLTKH KKIHSGEKAH QCEECGKCFG RRDHLTVHYK
660 670 680 690 700
SVHLGEKVWQ KYKATFHQCD VCKKIFKGKS SLEMHFRTHS GEKPYKCQIC
710 720 730 740 750
NQSFRIKKTL TKHLVIHSDA RPFNCQHCNA TFKRKDKLKY HIDHVHGIKS
760 770 780 790 800
PDDSLSTSEE KLMSLPMEYS SDDKIFQAET KQYLDQPKVY QSEAKTMLQN
810 820 830 840 850
VSAEVCVPVT LVPVQMPDTS SDLVPHTTTL PTSSHEMLPP QPQSTDYPRA
860 870 880 890 900
ADLAFLEKYT LTPQPANIVH PVRPEQMLDP REPSYLGTLL GLDSTAAVQN

MCSSEHRS
Length:908
Mass (Da):104,683
Last modified:February 20, 2007 - v4
Checksum:iC7D50D9BB45FAC8C
GO

Sequence cautioni

The sequence BAC29469 differs from that shown. Reason: Frameshift at position 15.Curated
The sequence BAC37731 differs from that shown. Reason: Frameshift at position 895.Curated
The sequence BAE37287 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti227 – 229LAK → ASE in AAH46465 (PubMed:15489334).Curated3
Sequence conflicti352I → V in AAH46465 (PubMed:15489334).Curated1
Sequence conflicti722P → H in BAC37731 (PubMed:16141072).Curated1
Sequence conflicti896A → T in AAH46465 (PubMed:15489334).Curated1
Sequence conflicti902C → S in AAH46465 (PubMed:15489334).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK036544 mRNA Translation: BAC29469.1 Frameshift.
AK037812 mRNA Translation: BAC29876.1
AK079719 mRNA Translation: BAC37731.1 Frameshift.
AK163302 mRNA Translation: BAE37287.1 Different initiation.
AL606536 Genomic DNA No translation available.
BC046465 mRNA Translation: AAH46465.3
CCDSiCCDS48385.1
RefSeqiNP_766231.2, NM_172643.5
XP_006529509.1, XM_006529446.3
XP_006529510.1, XM_006529447.3
XP_006529511.1, XM_006529448.3
UniGeneiMm.119711

Genome annotation databases

EnsembliENSMUST00000039867; ENSMUSP00000045570; ENSMUSG00000033964
GeneIDi226470
KEGGimmu:226470
UCSCiuc007cwg.2 mouse

Similar proteinsi

Entry informationi

Entry nameiZBT41_MOUSE
AccessioniPrimary (citable) accession number: Q811F1
Secondary accession number(s): A2A706
, Q8BI96, Q8BV67, Q8BYV8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 20, 2007
Last sequence update: February 20, 2007
Last modified: March 28, 2018
This is version 132 of the entry and version 4 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot

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