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Q810Z4

- Q810Z4_MOUSE

UniProt

Q810Z4 - Q810Z4_MOUSE

Protein
Submitted name:

PDK1

Gene
N/A
Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi
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    • History
      Entry version 79 (01 Oct 2014)
      Sequence version 1 (01 Jun 2003)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. 3-phosphoinositide-dependent protein kinase activity Source: Ensembl
    2. ATP binding Source: UniProtKB-KW

    GO - Biological processi

    1. activation of protein kinase B activity Source: Ensembl
    2. cellular response to insulin stimulus Source: Ensembl
    3. extrinsic apoptotic signaling pathway Source: Ensembl
    4. focal adhesion assembly Source: Ensembl
    5. intracellular signal transduction Source: Ensembl
    6. negative regulation of protein kinase activity Source: Ensembl
    7. negative regulation of transforming growth factor beta receptor signaling pathway Source: Ensembl
    8. peptidyl-threonine phosphorylation Source: Ensembl
    9. positive regulation of establishment of protein localization to plasma membrane Source: Ensembl
    10. regulation of I-kappaB kinase/NF-kappaB signaling Source: Ensembl

    Keywords - Ligandi

    ATP-bindingUniRule annotation, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    PDK1Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

    Subcellular locationi

    GO - Cellular componenti

    1. cytosol Source: Ensembl
    2. plasma membrane Source: Ensembl

    Expressioni

    Gene expression databases

    ArrayExpressiQ810Z4.
    BgeeiQ810Z4.
    GenevestigatoriQ810Z4.

    Interactioni

    Protein-protein interaction databases

    MINTiMINT-1581308.

    Structurei

    3D structure databases

    ProteinModelPortaliQ810Z4.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    HOVERGENiHBG098357.
    InParanoidiQ810Z4.

    Family and domain databases

    Gene3Di2.30.29.30. 2 hits.
    InterProiIPR011009. Kinase-like_dom.
    IPR011993. PH_like_dom.
    IPR000719. Prot_kinase_dom.
    IPR017441. Protein_kinase_ATP_BS.
    IPR002290. Ser/Thr_dual-sp_kinase_dom.
    IPR008271. Ser/Thr_kinase_AS.
    [Graphical view]
    PfamiPF00069. Pkinase. 1 hit.
    [Graphical view]
    SMARTiSM00220. S_TKc. 1 hit.
    [Graphical view]
    SUPFAMiSSF56112. SSF56112. 1 hit.
    PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
    PS50011. PROTEIN_KINASE_DOM. 1 hit.
    PS00108. PROTEIN_KINASE_ST. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    Q810Z4-1 [UniParc]FASTAAdd to Basket

    « Hide

    YDAVPIQSSV VLCSCPSPSM VRSQTEPGSS PGIPSGVSRQ GSTMDGTTAE    50
    ARPSTNPLQQ HPAQLPPQPR KKRPEDFKFG KILGEGSFST VVLARELATS 100
    REYAIKILEK RHIIKENKVP YVTRERDVMS RLDHPFFVKL YFTFQDDEKL 150
    YFGLSYAKNG ELLKYIRKIG SFDETCTRFY TAEIVSALEY LHGKGIIHRD 200
    LKPENILLNE DMHIQITDFG TAKVLSPESK QARANSFVGT AQYVSPELLT 250
    EKSACKSSDL WALGCIIYQL VAGLPPFRAG NEYLIFQKII KLEYHFPEKF 300
    FPKARDLVEK LLVLDATKRL GCEEMEGYGP LKAHPFFETI TWENLHQQTP 350
    PKLTAYLPAM SEDDEDCYGN YDNLLSQFGF MQVSSSSSSH SLSTVETSLP 400
    QRSGSNIEQY IHDLDTNSFE LDLQFSEDEK RLLLEKQAGG NPWHQFVENN 450
    LILKMGPVDK RKGLFARRRQ LLLTEGPHLY YVDPVNKVLK GEIPWSQELR 500
    PEAKNFKTFF VHTPNRTYYL MDPSGNAHKW CRKIQEVWRQ QYQSNPDAAV 550
    Q 551
    Length:551
    Mass (Da):62,870
    Last modified:June 1, 2003 - v1
    Checksum:iACC31D51439282F4
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY162410 Genomic DNA. Translation: AAO17164.1.
    UniGeneiMm.10504.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY162410 Genomic DNA. Translation: AAO17164.1 .
    UniGenei Mm.10504.

    3D structure databases

    ProteinModelPortali Q810Z4.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    MINTi MINT-1581308.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Phylogenomic databases

    HOVERGENi HBG098357.
    InParanoidi Q810Z4.

    Miscellaneous databases

    ChiTaRSi PDPK1. mouse.

    Gene expression databases

    ArrayExpressi Q810Z4.
    Bgeei Q810Z4.
    Genevestigatori Q810Z4.

    Family and domain databases

    Gene3Di 2.30.29.30. 2 hits.
    InterProi IPR011009. Kinase-like_dom.
    IPR011993. PH_like_dom.
    IPR000719. Prot_kinase_dom.
    IPR017441. Protein_kinase_ATP_BS.
    IPR002290. Ser/Thr_dual-sp_kinase_dom.
    IPR008271. Ser/Thr_kinase_AS.
    [Graphical view ]
    Pfami PF00069. Pkinase. 1 hit.
    [Graphical view ]
    SMARTi SM00220. S_TKc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56112. SSF56112. 1 hit.
    PROSITEi PS00107. PROTEIN_KINASE_ATP. 1 hit.
    PS50011. PROTEIN_KINASE_DOM. 1 hit.
    PS00108. PROTEIN_KINASE_ST. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Genomic Sequence Analysis in the Mouse T-complex Region."
      Brathwaite M., Waeltz P., Schlessinger D., Nagaraja R.
      Submitted (OCT-2002) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: 129/SvJImported.

    Entry informationi

    Entry nameiQ810Z4_MOUSE
    AccessioniPrimary (citable) accession number: Q810Z4
    Entry historyi
    Integrated into UniProtKB/TrEMBL: June 1, 2003
    Last sequence update: June 1, 2003
    Last modified: October 1, 2014
    This is version 79 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)