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Q810Z4

- Q810Z4_MOUSE

UniProt

Q810Z4 - Q810Z4_MOUSE

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Protein
Submitted name: PDK1
Gene
N/A
Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein predictedi

Functioni

GO - Molecular functioni

  1. 3-phosphoinositide-dependent protein kinase activity Source: Ensembl
  2. ATP binding Source: UniProtKB-KW
Complete GO annotation...

GO - Biological processi

  1. activation of protein kinase B activity Source: Ensembl
  2. cellular response to insulin stimulus Source: Ensembl
  3. extrinsic apoptotic signaling pathway Source: Ensembl
  4. focal adhesion assembly Source: Ensembl
  5. intracellular signal transduction Source: Ensembl
  6. negative regulation of protein kinase activity Source: Ensembl
  7. negative regulation of transforming growth factor beta receptor signaling pathway Source: Ensembl
  8. peptidyl-threonine phosphorylation Source: Ensembl
  9. positive regulation of establishment of protein localization to plasma membrane Source: Ensembl
  10. regulation of I-kappaB kinase/NF-kappaB signaling Source: Ensembl
Complete GO annotation...

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
PDK1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Subcellular locationi

GO - Cellular componenti

  1. cytosol Source: Ensembl
  2. plasma membrane Source: Ensembl
Complete GO annotation...

Expressioni

Gene expression databases

ArrayExpressiQ810Z4.
BgeeiQ810Z4.
GenevestigatoriQ810Z4.

Interactioni

Protein-protein interaction databases

MINTiMINT-1581308.

Structurei

3D structure databases

ProteinModelPortaliQ810Z4.

Family & Domainsi

Phylogenomic databases

HOVERGENiHBG098357.
InParanoidiQ810Z4.

Family and domain databases

Gene3Di2.30.29.30. 2 hits.
InterProiIPR011009. Kinase-like_dom.
IPR011993. PH_like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR002290. Ser/Thr_dual-sp_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
[Graphical view]
SMARTiSM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q810Z4-1 [UniParc]FASTAAdd to Basket

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YDAVPIQSSV VLCSCPSPSM VRSQTEPGSS PGIPSGVSRQ GSTMDGTTAE    50
ARPSTNPLQQ HPAQLPPQPR KKRPEDFKFG KILGEGSFST VVLARELATS 100
REYAIKILEK RHIIKENKVP YVTRERDVMS RLDHPFFVKL YFTFQDDEKL 150
YFGLSYAKNG ELLKYIRKIG SFDETCTRFY TAEIVSALEY LHGKGIIHRD 200
LKPENILLNE DMHIQITDFG TAKVLSPESK QARANSFVGT AQYVSPELLT 250
EKSACKSSDL WALGCIIYQL VAGLPPFRAG NEYLIFQKII KLEYHFPEKF 300
FPKARDLVEK LLVLDATKRL GCEEMEGYGP LKAHPFFETI TWENLHQQTP 350
PKLTAYLPAM SEDDEDCYGN YDNLLSQFGF MQVSSSSSSH SLSTVETSLP 400
QRSGSNIEQY IHDLDTNSFE LDLQFSEDEK RLLLEKQAGG NPWHQFVENN 450
LILKMGPVDK RKGLFARRRQ LLLTEGPHLY YVDPVNKVLK GEIPWSQELR 500
PEAKNFKTFF VHTPNRTYYL MDPSGNAHKW CRKIQEVWRQ QYQSNPDAAV 550
Q 551
Length:551
Mass (Da):62,870
Last modified:June 1, 2003 - v1
Checksum:iACC31D51439282F4
GO

Non-terminal residue

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY162410 Genomic DNA. Translation: AAO17164.1.
UniGeneiMm.10504.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY162410 Genomic DNA. Translation: AAO17164.1 .
UniGenei Mm.10504.

3D structure databases

ProteinModelPortali Q810Z4.
ModBasei Search...

Protein-protein interaction databases

MINTi MINT-1581308.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Phylogenomic databases

HOVERGENi HBG098357.
InParanoidi Q810Z4.

Miscellaneous databases

ChiTaRSi PDPK1. mouse.

Gene expression databases

ArrayExpressi Q810Z4.
Bgeei Q810Z4.
Genevestigatori Q810Z4.

Family and domain databases

Gene3Di 2.30.29.30. 2 hits.
InterProi IPR011009. Kinase-like_dom.
IPR011993. PH_like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR002290. Ser/Thr_dual-sp_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view ]
Pfami PF00069. Pkinase. 1 hit.
[Graphical view ]
SMARTi SM00220. S_TKc. 1 hit.
[Graphical view ]
SUPFAMi SSF56112. SSF56112. 1 hit.
PROSITEi PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Genomic Sequence Analysis in the Mouse T-complex Region."
    Brathwaite M., Waeltz P., Schlessinger D., Nagaraja R.
    Submitted (OCT-2002) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: 129/SvJImported.

Entry informationi

Entry nameiQ810Z4_MOUSE
AccessioniPrimary (citable) accession number: Q810Z4
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: June 1, 2003
Last modified: July 9, 2014
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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