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Protein

Normal mucosa of esophagus-specific gene 1 protein

Gene

Nmes1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Normal mucosa of esophagus-specific gene 1 protein
Gene namesi
Name:Nmes1
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 2

Organism-specific databases

MGIiMGI:3034182. AA467197.

Subcellular locationi

GO - Cellular componenti

  • mitochondrial respiratory chain complex IV Source: GO_Central
  • mitochondrion Source: MGI
  • nucleus Source: UniProtKB
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 8383Normal mucosa of esophagus-specific gene 1 proteinPRO_0000118824Add
BLAST

Proteomic databases

EPDiQ810Q5.
MaxQBiQ810Q5.
PaxDbiQ810Q5.
PRIDEiQ810Q5.

PTM databases

iPTMnetiQ810Q5.
PhosphoSiteiQ810Q5.

Expressioni

Tissue specificityi

Strongly expressed in vertebrae, brain, intestine and stomach.1 Publication

Developmental stagei

First detected at 8 dpc in the ossification center and the spinal cord. From this stage up to birth, expression extends throughout the bone tissue and strong expression is detected in the vertebrae. At 16 dpc, detected in the developing brain, including the prosencephalon, mesencephalon, diencephalon, telencephalon and rhombencephalon, and in the intestine. Faint expression at 16 dpc in the lung.1 Publication

Gene expression databases

BgeeiENSMUSG00000033213.
CleanExiMM_AA467197.
ExpressionAtlasiQ810Q5. baseline and differential.
GenevisibleiQ810Q5. MM.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000040781.

Family & Domainsi

Sequence similaritiesi

Belongs to the complex I NDUFA4 subunit family.Curated

Phylogenomic databases

eggNOGiENOG410J1F7. Eukaryota.
ENOG410YXE9. LUCA.
GeneTreeiENSGT00390000009277.
HOGENOMiHOG000261679.
HOVERGENiHBG052639.
InParanoidiQ810Q5.
OMAiQWKPVET.
OrthoDBiEOG091G11T6.
PhylomeDBiQ810Q5.
TreeFamiTF106383.

Family and domain databases

InterProiIPR010530. B12D.
[Graphical view]
PANTHERiPTHR14256. PTHR14256. 1 hit.
PfamiPF06522. B12D. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q810Q5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGVFQILMKN KELIPLAFFI SVAATGATSF ALYALKKTDV VIDRKRNPEP
60 70 80
WEMVDPTQPQ KLITINQQWK PVEELQKVRR ATR
Length:83
Mass (Da):9,584
Last modified:June 1, 2003 - v1
Checksum:i0550DCA98B74D941
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC049633 mRNA. Translation: AAH49633.1.
CCDSiCCDS38224.1.
RefSeqiNP_001004174.1. NM_001004174.1.
XP_006499936.1. XM_006499873.2.
UniGeneiMm.36783.

Genome annotation databases

EnsembliENSMUST00000047498; ENSMUSP00000040781; ENSMUSG00000033213.
ENSMUST00000110512; ENSMUSP00000106141; ENSMUSG00000033213.
GeneIDi433470.
KEGGimmu:433470.
UCSCiuc008may.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC049633 mRNA. Translation: AAH49633.1.
CCDSiCCDS38224.1.
RefSeqiNP_001004174.1. NM_001004174.1.
XP_006499936.1. XM_006499873.2.
UniGeneiMm.36783.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000040781.

PTM databases

iPTMnetiQ810Q5.
PhosphoSiteiQ810Q5.

Proteomic databases

EPDiQ810Q5.
MaxQBiQ810Q5.
PaxDbiQ810Q5.
PRIDEiQ810Q5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000047498; ENSMUSP00000040781; ENSMUSG00000033213.
ENSMUST00000110512; ENSMUSP00000106141; ENSMUSG00000033213.
GeneIDi433470.
KEGGimmu:433470.
UCSCiuc008may.1. mouse.

Organism-specific databases

MGIiMGI:3034182. AA467197.

Phylogenomic databases

eggNOGiENOG410J1F7. Eukaryota.
ENOG410YXE9. LUCA.
GeneTreeiENSGT00390000009277.
HOGENOMiHOG000261679.
HOVERGENiHBG052639.
InParanoidiQ810Q5.
OMAiQWKPVET.
OrthoDBiEOG091G11T6.
PhylomeDBiQ810Q5.
TreeFamiTF106383.

Miscellaneous databases

PROiQ810Q5.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000033213.
CleanExiMM_AA467197.
ExpressionAtlasiQ810Q5. baseline and differential.
GenevisibleiQ810Q5. MM.

Family and domain databases

InterProiIPR010530. B12D.
[Graphical view]
PANTHERiPTHR14256. PTHR14256. 1 hit.
PfamiPF06522. B12D. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiNMES1_MOUSE
AccessioniPrimary (citable) accession number: Q810Q5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 15, 2004
Last sequence update: June 1, 2003
Last modified: September 7, 2016
This is version 81 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.