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Protein

Protein THEM6

Gene

Them6

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Protein THEM6
Gene namesi
Name:Them6
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 15

Organism-specific databases

MGIiMGI:1925301. Them6.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2121Sequence analysisAdd
BLAST
Chaini22 – 207186Protein THEM6PRO_0000285637Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi188 – 1881N-linked (GlcNAc...)Sequence analysis
Modified residuei199 – 1991PhosphoserineBy similarity

Keywords - PTMi

Glycoprotein, Phosphoprotein

Proteomic databases

EPDiQ80ZW2.
MaxQBiQ80ZW2.
PaxDbiQ80ZW2.
PeptideAtlasiQ80ZW2.
PRIDEiQ80ZW2.

PTM databases

PhosphoSiteiQ80ZW2.
SwissPalmiQ80ZW2.

Expressioni

Gene expression databases

BgeeiENSMUSG00000056665.
CleanExiMM_4930572J05RIK.
GenevisibleiQ80ZW2. MM.

Interactioni

Protein-protein interaction databases

BioGridi230161. 7 interactions.
IntActiQ80ZW2. 7 interactions.
STRINGi10090.ENSMUSP00000069692.

Structurei

3D structure databases

ProteinModelPortaliQ80ZW2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the THEM6 family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiKOG4366. Eukaryota.
ENOG4111RKY. LUCA.
GeneTreeiENSGT00390000004859.
HOGENOMiHOG000249151.
HOVERGENiHBG059534.
InParanoidiQ80ZW2.
OMAiHHYMRNG.
OrthoDBiEOG091G11QD.
PhylomeDBiQ80ZW2.
TreeFamiTF324625.

Family and domain databases

Gene3Di3.10.129.10. 1 hit.
InterProiIPR029069. HotDog_dom.
[Graphical view]
SUPFAMiSSF54637. SSF54637. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q80ZW2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLELLVASLS LALAFFALLD GWYLVRVPCA VLRARLLQPR VRDLLAEQRY
60 70 80 90 100
AGRVLPSDLD LLLHMNNARY LREADVARAA HLTRCGVLGA LRDLNAHTVL
110 120 130 140 150
AASCARYRRS LRLFEPFEVH TRLQGWDDRA FYLEARFVSL RDGFVCALLR
160 170 180 190 200
FRQHVLGTSP DRVVQHLCKR RVEPPELPED LKHWISYNET SSQLLRAESG

LSDRKDQ
Length:207
Mass (Da):23,803
Last modified:June 1, 2003 - v1
Checksum:i26CF2FA726955063
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC047266 mRNA. Translation: AAH47266.1.
CCDSiCCDS27527.1.
RefSeqiNP_941009.1. NM_198607.1.
UniGeneiMm.268603.

Genome annotation databases

EnsembliENSMUST00000070923; ENSMUSP00000069692; ENSMUSG00000056665.
GeneIDi223626.
KEGGimmu:223626.
UCSCiuc007wfs.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC047266 mRNA. Translation: AAH47266.1.
CCDSiCCDS27527.1.
RefSeqiNP_941009.1. NM_198607.1.
UniGeneiMm.268603.

3D structure databases

ProteinModelPortaliQ80ZW2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi230161. 7 interactions.
IntActiQ80ZW2. 7 interactions.
STRINGi10090.ENSMUSP00000069692.

PTM databases

PhosphoSiteiQ80ZW2.
SwissPalmiQ80ZW2.

Proteomic databases

EPDiQ80ZW2.
MaxQBiQ80ZW2.
PaxDbiQ80ZW2.
PeptideAtlasiQ80ZW2.
PRIDEiQ80ZW2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000070923; ENSMUSP00000069692; ENSMUSG00000056665.
GeneIDi223626.
KEGGimmu:223626.
UCSCiuc007wfs.1. mouse.

Organism-specific databases

CTDi51337.
MGIiMGI:1925301. Them6.

Phylogenomic databases

eggNOGiKOG4366. Eukaryota.
ENOG4111RKY. LUCA.
GeneTreeiENSGT00390000004859.
HOGENOMiHOG000249151.
HOVERGENiHBG059534.
InParanoidiQ80ZW2.
OMAiHHYMRNG.
OrthoDBiEOG091G11QD.
PhylomeDBiQ80ZW2.
TreeFamiTF324625.

Miscellaneous databases

PROiQ80ZW2.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000056665.
CleanExiMM_4930572J05RIK.
GenevisibleiQ80ZW2. MM.

Family and domain databases

Gene3Di3.10.129.10. 1 hit.
InterProiIPR029069. HotDog_dom.
[Graphical view]
SUPFAMiSSF54637. SSF54637. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiTHEM6_MOUSE
AccessioniPrimary (citable) accession number: Q80ZW2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 1, 2007
Last sequence update: June 1, 2003
Last modified: September 7, 2016
This is version 84 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.