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Protein
Submitted name:

Cadherin-4

Gene

Cdh4

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Ligandi

CalciumSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Cadherin-4Imported
Submitted name:
Cdh4 proteinImported
Gene namesi
Name:Cdh4Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 2

Organism-specific databases

MGIiMGI:99218. Cdh4.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2020Sequence analysisAdd
BLAST
Chaini21 – 334314Sequence analysisPRO_5007323183Add
BLAST

Proteomic databases

TopDownProteomicsiQ80ZV4.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000000314.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini167 – 274108CadherinInterPro annotationAdd
BLAST

Keywords - Domaini

RepeatSAAS annotation, SignalSequence analysis, Transmembrane, Transmembrane helixSAAS annotation

Phylogenomic databases

eggNOGiKOG3594. Eukaryota.
ENOG410XQHI. LUCA.
GeneTreeiENSGT00760000118906.
HOGENOMiHOG000202453.
HOVERGENiHBG067298.
KOiK06797.

Family and domain databases

Gene3Di2.60.40.60. 2 hits.
InterProiIPR002126. Cadherin.
IPR015919. Cadherin-like.
IPR020894. Cadherin_CS.
IPR014868. Cadherin_pro_dom.
[Graphical view]
PfamiPF00028. Cadherin. 1 hit.
PF08758. Cadherin_pro. 1 hit.
[Graphical view]
PRINTSiPR00205. CADHERIN.
SMARTiSM00112. CA. 1 hit.
SM01055. Cadherin_pro. 1 hit.
[Graphical view]
SUPFAMiSSF49313. SSF49313. 3 hits.
PROSITEiPS00232. CADHERIN_1. 1 hit.
PS50268. CADHERIN_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q80ZV4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTTGSVLPLL LLGLSGALRA HREDLTVREA CKAGFSEEGY TALISPNVLE
60 70 80 90 100
GEKLLKVEFS SCVGTKGMQY ETNSLDFKVG ADGTVFATRE LKIPSEQVAF
110 120 130 140 150
TVTARERQSA EQWAAMVRLL VAQTSSAHSE HKKGQTVALD PSQPPNDTLL
160 170 180 190 200
PWPQHQSSGG LRRQKRDWVI PPINVPENSR GPFPQQLVRI RSDKDNDIPI
210 220 230 240 250
RYSITGVGAD QPPMEVFNID SMSGRMYVTR PMDREERASY HLRAHAVDMN
260 270 280 290 300
GNKVENPIDL YIYVIDMNDN RPEFINQVYN GSVDEGSKPG EASWGPHALH
310 320 330
GTWVWDCNVQ HCCPVSHTSR YRESAESRHC SNRE
Length:334
Mass (Da):37,315
Last modified:June 1, 2003 - v1
Checksum:iEAF5FBD829D5BBBE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL663028 Genomic DNA. No translation available.
AL663067 Genomic DNA. No translation available.
AL669921 Genomic DNA. No translation available.
BX000474 Genomic DNA. No translation available.
BX537257 Genomic DNA. No translation available.
BC047991 mRNA. Translation: AAH47991.1.
RefSeqiNP_001303652.1. NM_001316723.1.
NP_033997.1. NM_009867.3.
UniGeneiMm.184711.

Genome annotation databases

EnsembliENSMUST00000108911; ENSMUSP00000104539; ENSMUSG00000000305.
GeneIDi12561.
KEGGimmu:12561.
UCSCiuc008ohu.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL663028 Genomic DNA. No translation available.
AL663067 Genomic DNA. No translation available.
AL669921 Genomic DNA. No translation available.
BX000474 Genomic DNA. No translation available.
BX537257 Genomic DNA. No translation available.
BC047991 mRNA. Translation: AAH47991.1.
RefSeqiNP_001303652.1. NM_001316723.1.
NP_033997.1. NM_009867.3.
UniGeneiMm.184711.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000000314.

Proteomic databases

TopDownProteomicsiQ80ZV4.

Protocols and materials databases

DNASUi12561.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000108911; ENSMUSP00000104539; ENSMUSG00000000305.
GeneIDi12561.
KEGGimmu:12561.
UCSCiuc008ohu.2. mouse.

Organism-specific databases

CTDi1002.
MGIiMGI:99218. Cdh4.

Phylogenomic databases

eggNOGiKOG3594. Eukaryota.
ENOG410XQHI. LUCA.
GeneTreeiENSGT00760000118906.
HOGENOMiHOG000202453.
HOVERGENiHBG067298.
KOiK06797.

Miscellaneous databases

SOURCEiSearch...

Family and domain databases

Gene3Di2.60.40.60. 2 hits.
InterProiIPR002126. Cadherin.
IPR015919. Cadherin-like.
IPR020894. Cadherin_CS.
IPR014868. Cadherin_pro_dom.
[Graphical view]
PfamiPF00028. Cadherin. 1 hit.
PF08758. Cadherin_pro. 1 hit.
[Graphical view]
PRINTSiPR00205. CADHERIN.
SMARTiSM00112. CA. 1 hit.
SM01055. Cadherin_pro. 1 hit.
[Graphical view]
SUPFAMiSSF49313. SSF49313. 3 hits.
PROSITEiPS00232. CADHERIN_1. 1 hit.
PS50268. CADHERIN_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: LimbImported.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  3. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiQ80ZV4_MOUSE
AccessioniPrimary (citable) accession number: Q80ZV4
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: June 1, 2003
Last modified: June 8, 2016
This is version 104 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.