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Protein

Integral membrane protein GPR137

Gene

Gpr137

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Integral membrane protein GPR137
Alternative name(s):
Transmembrane 7 superfamily member 1-like 1 protein
Gene namesi
Name:Gpr137
Synonyms:Tm7sf1l1
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 19

Organism-specific databases

MGIiMGI:2147529. Gpr137.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 3131ExtracellularSequence analysisAdd
BLAST
Transmembranei32 – 5221HelicalSequence analysisAdd
BLAST
Topological domaini53 – 608CytoplasmicSequence analysis
Transmembranei61 – 8121HelicalSequence analysisAdd
BLAST
Topological domaini82 – 898ExtracellularSequence analysis
Transmembranei90 – 11021HelicalSequence analysisAdd
BLAST
Topological domaini111 – 14030CytoplasmicSequence analysisAdd
BLAST
Transmembranei141 – 16121HelicalSequence analysisAdd
BLAST
Topological domaini162 – 17514ExtracellularSequence analysisAdd
BLAST
Transmembranei176 – 19621HelicalSequence analysisAdd
BLAST
Topological domaini197 – 21721CytoplasmicSequence analysisAdd
BLAST
Transmembranei218 – 24225HelicalSequence analysisAdd
BLAST
Topological domaini243 – 27432ExtracellularSequence analysisAdd
BLAST
Transmembranei275 – 29521HelicalSequence analysisAdd
BLAST
Topological domaini296 – 396101CytoplasmicSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 396396Integral membrane protein GPR137PRO_0000269997Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi4 – 41N-linked (GlcNAc...)Sequence analysis
Glycosylationi257 – 2571N-linked (GlcNAc...)Sequence analysis

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDbiQ80ZU9.
PRIDEiQ80ZU9.

PTM databases

iPTMnetiQ80ZU9.
PhosphoSiteiQ80ZU9.

Expressioni

Gene expression databases

BgeeiENSMUSG00000024958.
CleanExiMM_GPR137.
ExpressionAtlasiQ80ZU9. baseline and differential.
GenevisibleiQ80ZU9. MM.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000025909.

Family & Domainsi

Sequence similaritiesi

Belongs to the GPR137 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410IGBD. Eukaryota.
ENOG410XQNA. LUCA.
GeneTreeiENSGT00390000008320.
HOGENOMiHOG000286020.
HOVERGENiHBG058911.
InParanoidiQ80ZU9.
OMAiFDRAHCE.
OrthoDBiEOG091G08XG.
PhylomeDBiQ80ZU9.
TreeFamiTF329003.

Family and domain databases

InterProiIPR029723. GPR137.
[Graphical view]
PANTHERiPTHR15146. PTHR15146. 1 hit.

Sequencei

Sequence statusi: Complete.

Q80ZU9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MESNLSGLVP AAGLVPALPP TVTLGLTAAY TALYALLFFS VYAQLWLVLL
60 70 80 90 100
YGHKRLSYQT VFLALCLLWA ALRTTLFSFY FRDTPRANRL GPLPFWLLYC
110 120 130 140 150
CPVCLQFFTL TLMNLYFVQV VFKAKAKRRP EMSRGLLAVR GAFVGASLLF
160 170 180 190 200
LLVNVLCAVL SRQRQAQPWV LLLVRVLVSD SLFVICALSL AACLCLVARR
210 220 230 240 250
APSTSIYLEA KGTSVCQAAA IGGAMVLLYA SRACYNLAAL ALAPRSRLDA
260 270 280 290 300
FDYDWYNVSD QADLVNDLGN KGYLVFGLIL FVWELLPTTL LVGFFRVHRP
310 320 330 340 350
PQDLSTSRIL NGQVFGSRSY FFDRAGHCED EGCSWEHSRS ESTSMSGSLG
360 370 380 390
SGSWYGAIGR EPGWGGASQT RTTPLLFSQV PGPGSHHHSL YSTPQT
Length:396
Mass (Da):43,574
Last modified:June 1, 2003 - v1
Checksum:i4CA45B03848952BF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC048078 mRNA. Translation: AAH48078.1.
AY255566 mRNA. Translation: AAO85078.1.
CCDSiCCDS29512.1.
RefSeqiNP_001170831.1. NM_001177360.1.
NP_997103.1. NM_207220.2.
UniGeneiMm.276555.

Genome annotation databases

EnsembliENSMUST00000025909; ENSMUSP00000025909; ENSMUSG00000024958.
ENSMUST00000166115; ENSMUSP00000130969; ENSMUSG00000024958.
GeneIDi107173.
KEGGimmu:107173.
UCSCiuc008gjk.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC048078 mRNA. Translation: AAH48078.1.
AY255566 mRNA. Translation: AAO85078.1.
CCDSiCCDS29512.1.
RefSeqiNP_001170831.1. NM_001177360.1.
NP_997103.1. NM_207220.2.
UniGeneiMm.276555.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000025909.

PTM databases

iPTMnetiQ80ZU9.
PhosphoSiteiQ80ZU9.

Proteomic databases

PaxDbiQ80ZU9.
PRIDEiQ80ZU9.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000025909; ENSMUSP00000025909; ENSMUSG00000024958.
ENSMUST00000166115; ENSMUSP00000130969; ENSMUSG00000024958.
GeneIDi107173.
KEGGimmu:107173.
UCSCiuc008gjk.2. mouse.

Organism-specific databases

CTDi56834.
MGIiMGI:2147529. Gpr137.

Phylogenomic databases

eggNOGiENOG410IGBD. Eukaryota.
ENOG410XQNA. LUCA.
GeneTreeiENSGT00390000008320.
HOGENOMiHOG000286020.
HOVERGENiHBG058911.
InParanoidiQ80ZU9.
OMAiFDRAHCE.
OrthoDBiEOG091G08XG.
PhylomeDBiQ80ZU9.
TreeFamiTF329003.

Miscellaneous databases

PROiQ80ZU9.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000024958.
CleanExiMM_GPR137.
ExpressionAtlasiQ80ZU9. baseline and differential.
GenevisibleiQ80ZU9. MM.

Family and domain databases

InterProiIPR029723. GPR137.
[Graphical view]
PANTHERiPTHR15146. PTHR15146. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiG137A_MOUSE
AccessioniPrimary (citable) accession number: Q80ZU9
Secondary accession number(s): Q80UB6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 9, 2007
Last sequence update: June 1, 2003
Last modified: September 7, 2016
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.