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Q80ZU7

- BPIB3_MOUSE

UniProt

Q80ZU7 - BPIB3_MOUSE

Protein

BPI fold-containing family B member 3

Gene

Bpifb3

Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 76 (01 Oct 2014)
      Sequence version 2 (24 May 2005)
      Previous versions | rss
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    Functioni

    May have the capacity to recognize and bind specific classes of odorants. May act as a carrier molecule, transporting odorants across the mucus layer to access receptor sites. May serve as a primary defense mechanism by recognizing and removing potentially harmful odorants or pathogenic microorganisms from the mucosa or clearing excess odorant from mucus to enable new odorant stimuli to be received By similarity.By similarity

    GO - Molecular functioni

    1. lipid binding Source: InterPro

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    BPI fold-containing family B member 3
    Alternative name(s):
    Ligand-binding protein RYA3
    Long palate, lung and nasal epithelium carcinoma-associated protein 3
    Gene namesi
    Name:Bpifb3
    Synonyms:Lplunc3, Rya3
    OrganismiMus musculus (Mouse)
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 2

    Organism-specific databases

    MGIiMGI:2675077. Bpifb3.

    Subcellular locationi

    Secreted By similarity

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB
    2. extracellular region Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Secreted

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 2020Sequence AnalysisAdd
    BLAST
    Chaini21 – 473453BPI fold-containing family B member 3PRO_0000017171Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Glycosylationi139 – 1391N-linked (GlcNAc...)Sequence Analysis
    Disulfide bondi161 ↔ 196By similarity

    Keywords - PTMi

    Disulfide bond, Glycoprotein

    Proteomic databases

    PRIDEiQ80ZU7.

    Expressioni

    Gene expression databases

    BgeeiQ80ZU7.
    GenevestigatoriQ80ZU7.

    Structurei

    3D structure databases

    ProteinModelPortaliQ80ZU7.
    SMRiQ80ZU7. Positions 88-448.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Keywords - Domaini

    Signal

    Phylogenomic databases

    eggNOGiNOG317196.
    GeneTreeiENSGT00730000110772.
    HOGENOMiHOG000231741.
    HOVERGENiHBG050718.
    InParanoidiA2APD1.
    OMAiPLISNQY.
    OrthoDBiEOG715Q45.
    PhylomeDBiQ80ZU7.
    TreeFamiTF315617.

    Family and domain databases

    InterProiIPR017943. Bactericidal_perm-incr_a/b_dom.
    IPR001124. Lipid-bd_serum_glycop_C.
    IPR017942. Lipid-bd_serum_glycop_N.
    [Graphical view]
    PfamiPF01273. LBP_BPI_CETP. 1 hit.
    PF02886. LBP_BPI_CETP_C. 1 hit.
    [Graphical view]
    SMARTiSM00328. BPI1. 1 hit.
    SM00329. BPI2. 1 hit.
    [Graphical view]
    SUPFAMiSSF55394. SSF55394. 2 hits.

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q80ZU7-1 [UniParc]FASTAAdd to Basket

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    MMLGVYTLLL LWGLATPCLG LLETVGTLAR IDKDELGKAI QNSLVGGPIL    50
    QNVLGTVTSV NQGLLGAGGL LGGGGLLSYG GIFSLVEELS GLKIEELTLP 100
    KVSLKLLPGV GVQLNLHTKV SLHGSGPLVG LLQLAAEVNV SSKVALGMSP 150
    RGTPILVLKR CSTLLGHISL MSGLLPTPIF GLVEQTLCKV LPGLLCPVVD 200
    SVLSVVNELL GATLSLVPLG PLGSVEFTLA TLPLISNQYI ELDINPIVKS 250
    IAGDVIDFPK PRIPVKVPPK EDHTSQVTVP LYLFSTVFGL LQTNGALDLD 300
    ITPEMVPRNV PLTTTDLAAL APEALGKLPP AQHLLLSLRV TKSPMVLLQN 350
    KKATVSIPVT IHVLSSVPQG TPVALFQLNG VMTLNAHLAP SSTKLHISLS 400
    LERLSVQLAS SFPQPFDASR LEEWLSDVVR AAYMQRLNEH LEVGIPLPKI 450
    LNVNFANSVV DIIENAVVLT VAP 473
    Length:473
    Mass (Da):49,885
    Last modified:May 24, 2005 - v2
    Checksum:i246BF7BAEB328913
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL833803 Genomic DNA. Translation: CAM18460.1.
    BC048084 mRNA. Translation: AAH48084.2.
    CCDSiCCDS16921.1.
    RefSeqiNP_919338.2. NM_194357.1.
    XP_006499875.1. XM_006499812.1.
    UniGeneiMm.55392.

    Genome annotation databases

    EnsembliENSMUST00000088950; ENSMUSP00000086342; ENSMUSG00000068008.
    ENSMUST00000109760; ENSMUSP00000105382; ENSMUSG00000068008.
    GeneIDi378700.
    KEGGimmu:378700.
    UCSCiuc008nip.1. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL833803 Genomic DNA. Translation: CAM18460.1 .
    BC048084 mRNA. Translation: AAH48084.2 .
    CCDSi CCDS16921.1.
    RefSeqi NP_919338.2. NM_194357.1.
    XP_006499875.1. XM_006499812.1.
    UniGenei Mm.55392.

    3D structure databases

    ProteinModelPortali Q80ZU7.
    SMRi Q80ZU7. Positions 88-448.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi Q80ZU7.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000088950 ; ENSMUSP00000086342 ; ENSMUSG00000068008 .
    ENSMUST00000109760 ; ENSMUSP00000105382 ; ENSMUSG00000068008 .
    GeneIDi 378700.
    KEGGi mmu:378700.
    UCSCi uc008nip.1. mouse.

    Organism-specific databases

    CTDi 359710.
    MGIi MGI:2675077. Bpifb3.

    Phylogenomic databases

    eggNOGi NOG317196.
    GeneTreei ENSGT00730000110772.
    HOGENOMi HOG000231741.
    HOVERGENi HBG050718.
    InParanoidi A2APD1.
    OMAi PLISNQY.
    OrthoDBi EOG715Q45.
    PhylomeDBi Q80ZU7.
    TreeFami TF315617.

    Miscellaneous databases

    NextBioi 400991.
    PROi Q80ZU7.
    SOURCEi Search...

    Gene expression databases

    Bgeei Q80ZU7.
    Genevestigatori Q80ZU7.

    Family and domain databases

    InterProi IPR017943. Bactericidal_perm-incr_a/b_dom.
    IPR001124. Lipid-bd_serum_glycop_C.
    IPR017942. Lipid-bd_serum_glycop_N.
    [Graphical view ]
    Pfami PF01273. LBP_BPI_CETP. 1 hit.
    PF02886. LBP_BPI_CETP_C. 1 hit.
    [Graphical view ]
    SMARTi SM00328. BPI1. 1 hit.
    SM00329. BPI2. 1 hit.
    [Graphical view ]
    SUPFAMi SSF55394. SSF55394. 2 hits.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6J.
    2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: C57BL/6.
      Tissue: Olfactory epithelium.

    Entry informationi

    Entry nameiBPIB3_MOUSE
    AccessioniPrimary (citable) accession number: Q80ZU7
    Secondary accession number(s): A2APD1
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: August 29, 2003
    Last sequence update: May 24, 2005
    Last modified: October 1, 2014
    This is version 76 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. MGD cross-references
      Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3