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Protein

ADP-ribosylation factor-like protein 5A

Gene

Arl5a

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Lacks ADP-ribosylation enhancing activity.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei159GTP; via amide nitrogenBy similarity1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi23 – 30GTPBy similarity8
Nucleotide bindingi66 – 70GTPBy similarity5
Nucleotide bindingi125 – 128GTPBy similarity4

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandGTP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
ADP-ribosylation factor-like protein 5A
Gene namesi
Name:Arl5a
Synonyms:Arl5
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 2

Organism-specific databases

MGIiMGI:1922673 Arl5a

Subcellular locationi

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedSequence analysis
ChainiPRO_00002074682 – 179ADP-ribosylation factor-like protein 5AAdd BLAST178

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Lipidationi2N-myristoyl glycineSequence analysis1

Keywords - PTMi

Lipoprotein, Myristate

Proteomic databases

MaxQBiQ80ZU0
PaxDbiQ80ZU0
PRIDEiQ80ZU0

PTM databases

PhosphoSitePlusiQ80ZU0

Expressioni

Gene expression databases

BgeeiENSMUSG00000036093
CleanExiMM_ARL5A
ExpressionAtlasiQ80ZU0 baseline and differential
GenevisibleiQ80ZU0 MM

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000041756

Structurei

3D structure databases

ProteinModelPortaliQ80ZU0
SMRiQ80ZU0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the small GTPase superfamily. Arf family.Curated

Phylogenomic databases

eggNOGiKOG0070 Eukaryota
COG1100 LUCA
GeneTreeiENSGT00910000144027
HOGENOMiHOG000163691
HOVERGENiHBG002073
InParanoidiQ80ZU0
KOiK07949
OMAiDVKGCMS
OrthoDBiEOG091G0W92
PhylomeDBiQ80ZU0
TreeFamiTF105465

Family and domain databases

InterProiView protein in InterPro
IPR027417 P-loop_NTPase
IPR005225 Small_GTP-bd_dom
IPR024156 Small_GTPase_ARF
IPR006689 Small_GTPase_ARF/SAR
PfamiView protein in Pfam
PF00025 Arf, 1 hit
PRINTSiPR00328 SAR1GTPBP
SUPFAMiSSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR00231 small_GTP, 1 hit
PROSITEiView protein in PROSITE
PS51417 ARF, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q80ZU0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGILFTRIWR LFNHQEHKVI IVGLDNAGKT TILYQFSMNE VVHTSPTIGS
60 70 80 90 100
NVEEIVVNNT RFLMWDIGGQ ESLRPSWNTY YTNTEFVIVV VDSTDRERIS
110 120 130 140 150
VTREELYKML AHEDLRKAGL LIFANKQDVK ECMTVAEISQ FLKLTSIKDH
160 170
QWHIQACCAL TGEGLCQGLE WMMSRLKIR
Length:179
Mass (Da):20,724
Last modified:June 1, 2003 - v1
Checksum:i527CF73C5DB049EA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC048170 mRNA Translation: AAH48170.1
CCDSiCCDS16033.1
RefSeqiNP_892039.1, NM_182994.2
UniGeneiMm.314378

Genome annotation databases

EnsembliENSMUST00000036541; ENSMUSP00000041756; ENSMUSG00000036093
GeneIDi75423
KEGGimmu:75423
UCSCiuc008jqy.1 mouse

Similar proteinsi

Entry informationi

Entry nameiARL5A_MOUSE
AccessioniPrimary (citable) accession number: Q80ZU0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 10, 2004
Last sequence update: June 1, 2003
Last modified: March 28, 2018
This is version 114 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health