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Protein

ADP-ribosylation factor-like protein 5A

Gene

Arl5a

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Lacks ADP-ribosylation enhancing activity.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei159GTP; via amide nitrogenBy similarity1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi23 – 30GTPBy similarity8
Nucleotide bindingi66 – 70GTPBy similarity5
Nucleotide bindingi125 – 128GTPBy similarity4

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandGTP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
ADP-ribosylation factor-like protein 5A
Gene namesi
Name:Arl5a
Synonyms:Arl5
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 2

Organism-specific databases

MGIiMGI:1922673. Arl5a.

Subcellular locationi

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedSequence analysis
ChainiPRO_00002074682 – 179ADP-ribosylation factor-like protein 5AAdd BLAST178

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Lipidationi2N-myristoyl glycineSequence analysis1

Keywords - PTMi

Lipoprotein, Myristate

Proteomic databases

MaxQBiQ80ZU0.
PaxDbiQ80ZU0.
PRIDEiQ80ZU0.

PTM databases

PhosphoSitePlusiQ80ZU0.

Expressioni

Gene expression databases

BgeeiENSMUSG00000036093.
CleanExiMM_ARL5A.
ExpressionAtlasiQ80ZU0. baseline and differential.
GenevisibleiQ80ZU0. MM.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000041756.

Structurei

3D structure databases

ProteinModelPortaliQ80ZU0.
SMRiQ80ZU0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the small GTPase superfamily. Arf family.Curated

Phylogenomic databases

eggNOGiKOG0070. Eukaryota.
COG1100. LUCA.
GeneTreeiENSGT00890000139376.
HOGENOMiHOG000163691.
HOVERGENiHBG002073.
InParanoidiQ80ZU0.
KOiK07949.
OMAiDVKGCMS.
OrthoDBiEOG091G0W92.
PhylomeDBiQ80ZU0.
TreeFamiTF105465.

Family and domain databases

InterProiView protein in InterPro
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR024156. Small_GTPase_ARF.
IPR006689. Small_GTPase_ARF/SAR.
PfamiView protein in Pfam
PF00025. Arf. 1 hit.
PRINTSiPR00328. SAR1GTPBP.
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00231. small_GTP. 1 hit.
PROSITEiView protein in PROSITE
PS51417. ARF. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q80ZU0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGILFTRIWR LFNHQEHKVI IVGLDNAGKT TILYQFSMNE VVHTSPTIGS
60 70 80 90 100
NVEEIVVNNT RFLMWDIGGQ ESLRPSWNTY YTNTEFVIVV VDSTDRERIS
110 120 130 140 150
VTREELYKML AHEDLRKAGL LIFANKQDVK ECMTVAEISQ FLKLTSIKDH
160 170
QWHIQACCAL TGEGLCQGLE WMMSRLKIR
Length:179
Mass (Da):20,724
Last modified:June 1, 2003 - v1
Checksum:i527CF73C5DB049EA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC048170 mRNA. Translation: AAH48170.1.
CCDSiCCDS16033.1.
RefSeqiNP_892039.1. NM_182994.2.
UniGeneiMm.314378.

Genome annotation databases

EnsembliENSMUST00000036541; ENSMUSP00000041756; ENSMUSG00000036093.
GeneIDi75423.
KEGGimmu:75423.
UCSCiuc008jqy.1. mouse.

Similar proteinsi

Entry informationi

Entry nameiARL5A_MOUSE
AccessioniPrimary (citable) accession number: Q80ZU0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 10, 2004
Last sequence update: June 1, 2003
Last modified: November 22, 2017
This is version 112 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families