Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

ADP-ribosylation factor-like protein 5A

Gene

Arl5a

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Lacks ADP-ribosylation enhancing activity.By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei159 – 1591GTP; via amide nitrogenBy similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi23 – 308GTPBy similarity
Nucleotide bindingi66 – 705GTPBy similarity
Nucleotide bindingi125 – 1284GTPBy similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Ligandi

GTP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
ADP-ribosylation factor-like protein 5A
Gene namesi
Name:Arl5a
Synonyms:Arl5
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 2

Organism-specific databases

MGIiMGI:1922673. Arl5a.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methionineiRemovedSequence analysis
Chaini2 – 179178ADP-ribosylation factor-like protein 5APRO_0000207468Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Lipidationi2 – 21N-myristoyl glycineSequence analysis

Keywords - PTMi

Lipoprotein, Myristate

Proteomic databases

MaxQBiQ80ZU0.
PaxDbiQ80ZU0.
PRIDEiQ80ZU0.

PTM databases

PhosphoSiteiQ80ZU0.

Expressioni

Gene expression databases

BgeeiENSMUSG00000036093.
CleanExiMM_ARL5A.
ExpressionAtlasiQ80ZU0. baseline and differential.
GenevisibleiQ80ZU0. MM.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000041756.

Structurei

3D structure databases

ProteinModelPortaliQ80ZU0.
SMRiQ80ZU0. Positions 16-175.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the small GTPase superfamily. Arf family.Curated

Phylogenomic databases

eggNOGiKOG0070. Eukaryota.
COG1100. LUCA.
GeneTreeiENSGT00780000121855.
HOGENOMiHOG000163691.
HOVERGENiHBG002073.
InParanoidiQ80ZU0.
KOiK07949.
OMAiDVKGCMS.
OrthoDBiEOG091G0W92.
PhylomeDBiQ80ZU0.
TreeFamiTF105465.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR024156. Small_GTPase_ARF.
IPR006689. Small_GTPase_ARF/SAR.
[Graphical view]
PfamiPF00025. Arf. 1 hit.
[Graphical view]
PRINTSiPR00328. SAR1GTPBP.
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00231. small_GTP. 1 hit.
PROSITEiPS51417. ARF. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q80ZU0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGILFTRIWR LFNHQEHKVI IVGLDNAGKT TILYQFSMNE VVHTSPTIGS
60 70 80 90 100
NVEEIVVNNT RFLMWDIGGQ ESLRPSWNTY YTNTEFVIVV VDSTDRERIS
110 120 130 140 150
VTREELYKML AHEDLRKAGL LIFANKQDVK ECMTVAEISQ FLKLTSIKDH
160 170
QWHIQACCAL TGEGLCQGLE WMMSRLKIR
Length:179
Mass (Da):20,724
Last modified:June 1, 2003 - v1
Checksum:i527CF73C5DB049EA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC048170 mRNA. Translation: AAH48170.1.
CCDSiCCDS16033.1.
RefSeqiNP_892039.1. NM_182994.2.
UniGeneiMm.314378.

Genome annotation databases

EnsembliENSMUST00000036541; ENSMUSP00000041756; ENSMUSG00000036093.
GeneIDi75423.
KEGGimmu:75423.
UCSCiuc008jqy.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC048170 mRNA. Translation: AAH48170.1.
CCDSiCCDS16033.1.
RefSeqiNP_892039.1. NM_182994.2.
UniGeneiMm.314378.

3D structure databases

ProteinModelPortaliQ80ZU0.
SMRiQ80ZU0. Positions 16-175.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000041756.

PTM databases

PhosphoSiteiQ80ZU0.

Proteomic databases

MaxQBiQ80ZU0.
PaxDbiQ80ZU0.
PRIDEiQ80ZU0.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000036541; ENSMUSP00000041756; ENSMUSG00000036093.
GeneIDi75423.
KEGGimmu:75423.
UCSCiuc008jqy.1. mouse.

Organism-specific databases

CTDi26225.
MGIiMGI:1922673. Arl5a.

Phylogenomic databases

eggNOGiKOG0070. Eukaryota.
COG1100. LUCA.
GeneTreeiENSGT00780000121855.
HOGENOMiHOG000163691.
HOVERGENiHBG002073.
InParanoidiQ80ZU0.
KOiK07949.
OMAiDVKGCMS.
OrthoDBiEOG091G0W92.
PhylomeDBiQ80ZU0.
TreeFamiTF105465.

Miscellaneous databases

PROiQ80ZU0.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000036093.
CleanExiMM_ARL5A.
ExpressionAtlasiQ80ZU0. baseline and differential.
GenevisibleiQ80ZU0. MM.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR024156. Small_GTPase_ARF.
IPR006689. Small_GTPase_ARF/SAR.
[Graphical view]
PfamiPF00025. Arf. 1 hit.
[Graphical view]
PRINTSiPR00328. SAR1GTPBP.
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00231. small_GTP. 1 hit.
PROSITEiPS51417. ARF. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiARL5A_MOUSE
AccessioniPrimary (citable) accession number: Q80ZU0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 10, 2004
Last sequence update: June 1, 2003
Last modified: September 7, 2016
This is version 101 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.