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Q80ZF5

- Q80ZF5_RAT

UniProt

Q80ZF5 - Q80ZF5_RAT

Protein
Submitted name:

Obscurin

Gene

Obscn

Organism
Rattus norvegicus (Rat)
Status
Unreviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 77 (01 Oct 2014)
      Sequence version 1 (01 Jun 2003)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. ankyrin binding Source: BHF-UCL
    2. protein binding Source: RGD
    3. Rho guanyl-nucleotide exchange factor activity Source: RGD
    4. structural constituent of muscle Source: BHF-UCL

    GO - Biological processi

    1. positive regulation of Rho GTPase activity Source: GOC
    2. protein localization to M-band Source: BHF-UCL

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    ObscurinImported
    Gene namesi
    Name:ObscnImported
    Synonyms:ObscurinImported
    OrganismiRattus norvegicus (Rat)Imported
    Taxonomic identifieri10116 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

    Organism-specific databases

    RGDi631335. Obscn.

    Subcellular locationi

    GO - Cellular componenti

    1. M band Source: BHF-UCL
    2. sarcomere Source: RGD
    3. Z disc Source: BHF-UCL

    PTM / Processingi

    Proteomic databases

    PaxDbiQ80ZF5.
    PRIDEiQ80ZF5.

    PTM databases

    PhosphoSiteiQ80ZF5.

    Expressioni

    Gene expression databases

    GenevestigatoriQ80ZF5.

    Interactioni

    Protein-protein interaction databases

    STRINGi10116.ENSRNOP00000029928.

    Structurei

    3D structure databases

    ProteinModelPortaliQ80ZF5.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    eggNOGiCOG0515.
    HOGENOMiHOG000202800.
    HOVERGENiHBG099610.
    InParanoidiQ80ZF5.
    PhylomeDBiQ80ZF5.

    Family and domain databases

    Gene3Di1.20.900.10. 1 hit.
    2.30.29.30. 1 hit.
    2.60.40.10. 2 hits.
    InterProiIPR000219. DH-domain.
    IPR007110. Ig-like_dom.
    IPR013783. Ig-like_fold.
    IPR013098. Ig_I-set.
    IPR003598. Ig_sub2.
    IPR020682. Obscurin-myosin_light-ch_kin.
    IPR001849. PH_domain.
    IPR011993. PH_like_dom.
    [Graphical view]
    PANTHERiPTHR19897:SF17. PTHR19897:SF17. 1 hit.
    PfamiPF07679. I-set. 2 hits.
    PF00621. RhoGEF. 1 hit.
    [Graphical view]
    SMARTiSM00408. IGc2. 2 hits.
    SM00233. PH. 1 hit.
    [Graphical view]
    SUPFAMiSSF48065. SSF48065. 1 hit.
    PROSITEiPS50010. DH_2. 1 hit.
    PS50835. IG_LIKE. 2 hits.
    PS50003. PH_DOMAIN. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    Q80ZF5-1 [UniParc]FASTAAdd to Basket

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    GTSKDPTQPP PPPLQHYLEQ PVERVQKYQA LLKELIRNKA RNRQNCALLE    50
    QAYAVVSALP QRAENKLHVS LMENYPGTLE ALGEPIRQGH FIVWEGAPGA 100
    RMPWKGHNRH VFLFRNHLVI CKPRRDSRTD TFSYVFRNMM KLNSIDLNDQ 150
    VEGDDRAFEV WHEREDSVRK YLLQARTVII KNSWVKEICG IQQRLAQPVW 200
    CPPEFEEELA DCTAELGETV KLACRVTGTP KPIVSWYKDG KPVEVDPHHI 250
    LIEDPDGSCT LILDNLTGID SGQYMCFAAS AAGNASTLGK ILVQVPPRFV 300
    NKVRATPFVE GEDAQITCTV EGAPYPQIRW YKDGALLTLG NRYRMVNEPR 350
    SGMLVLVIQA ASKEDLGHYE CELVNRLGST RCGGELYMQS PALRAWDQHH 400
    REQLVAAVEV TEQETKVPKK TVIIEETITT VVKSPRGRRQ SPSKSPSRSP 450
    SRRSASPRRP GLLAPEMLYP PGTSPSRRLE VEQGRKAPVP ALYVTEAEAH 500
    TPASQPQPKW LEVEETIEVR VKKTGSRGAS PVREMTSHGE GILFTLPGAI 550
    PARDPNANNS NNKSVYQGAR TWGPAVVHVG EPFVFQVDSV GNVDWAAAGP 600
    ESEEVRASQE EENVEKEEGG SDGDENTFLM EEPQDTDSLQ GRDPKILTHN 650
    GRVLTLADLE DYVPQEGETF GCGDPTPSAP DEPPCEVSVL QREIGELTVG 700
    QPVLLNVGRP PGPSATPSFF RPSSQVHSPE SVSFLLREAW TGPASAAPWT 750
    SSFHTHVQSS VDGGHGSFKT EVSTQTVSFG AVGETVTLHI DPDGGEAPGP 800
    SQG 803
    Length:803
    Mass (Da):88,463
    Last modified:June 1, 2003 - v1
    Checksum:iA1BC0789EBF277D6
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY167411 mRNA. Translation: AAO34127.1.
    UniGeneiRn.232158.
    Rn.40889.

    Genome annotation databases

    UCSCiRGD:631335. rat.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY167411 mRNA. Translation: AAO34127.1 .
    UniGenei Rn.232158.
    Rn.40889.

    3D structure databases

    ProteinModelPortali Q80ZF5.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 10116.ENSRNOP00000029928.

    PTM databases

    PhosphoSitei Q80ZF5.

    Proteomic databases

    PaxDbi Q80ZF5.
    PRIDEi Q80ZF5.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    UCSCi RGD:631335. rat.

    Organism-specific databases

    RGDi 631335. Obscn.

    Phylogenomic databases

    eggNOGi COG0515.
    HOGENOMi HOG000202800.
    HOVERGENi HBG099610.
    InParanoidi Q80ZF5.
    PhylomeDBi Q80ZF5.

    Gene expression databases

    Genevestigatori Q80ZF5.

    Family and domain databases

    Gene3Di 1.20.900.10. 1 hit.
    2.30.29.30. 1 hit.
    2.60.40.10. 2 hits.
    InterProi IPR000219. DH-domain.
    IPR007110. Ig-like_dom.
    IPR013783. Ig-like_fold.
    IPR013098. Ig_I-set.
    IPR003598. Ig_sub2.
    IPR020682. Obscurin-myosin_light-ch_kin.
    IPR001849. PH_domain.
    IPR011993. PH_like_dom.
    [Graphical view ]
    PANTHERi PTHR19897:SF17. PTHR19897:SF17. 1 hit.
    Pfami PF07679. I-set. 2 hits.
    PF00621. RhoGEF. 1 hit.
    [Graphical view ]
    SMARTi SM00408. IGc2. 2 hits.
    SM00233. PH. 1 hit.
    [Graphical view ]
    SUPFAMi SSF48065. SSF48065. 1 hit.
    PROSITEi PS50010. DH_2. 1 hit.
    PS50835. IG_LIKE. 2 hits.
    PS50003. PH_DOMAIN. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: Sprague-DawleyImported.

    Entry informationi

    Entry nameiQ80ZF5_RAT
    AccessioniPrimary (citable) accession number: Q80ZF5
    Entry historyi
    Integrated into UniProtKB/TrEMBL: June 1, 2003
    Last sequence update: June 1, 2003
    Last modified: October 1, 2014
    This is version 77 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)