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Q80ZF5

- Q80ZF5_RAT

UniProt

Q80ZF5 - Q80ZF5_RAT

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Protein
Submitted name:

Obscurin

Gene

Obscn

Organism
Rattus norvegicus (Rat)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. ankyrin binding Source: BHF-UCL
  2. Rho guanyl-nucleotide exchange factor activity Source: RGD
  3. structural constituent of muscle Source: BHF-UCL

GO - Biological processi

  1. positive regulation of Rho GTPase activity Source: GOC
  2. protein localization to M-band Source: BHF-UCL
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
ObscurinImported
Gene namesi
Name:ObscnImported
Synonyms:ObscurinImported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

Organism-specific databases

RGDi631335. Obscn.

Subcellular locationi

GO - Cellular componenti

  1. M band Source: BHF-UCL
  2. sarcomere Source: RGD
  3. Z disc Source: BHF-UCL
Complete GO annotation...

PTM / Processingi

Proteomic databases

PaxDbiQ80ZF5.
PRIDEiQ80ZF5.

PTM databases

PhosphoSiteiQ80ZF5.

Expressioni

Gene expression databases

GenevestigatoriQ80ZF5.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000029928.

Structurei

3D structure databases

ProteinModelPortaliQ80ZF5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiCOG0515.
HOGENOMiHOG000202800.
HOVERGENiHBG099610.
PhylomeDBiQ80ZF5.

Family and domain databases

Gene3Di1.20.900.10. 1 hit.
2.30.29.30. 1 hit.
2.60.40.10. 2 hits.
InterProiIPR000219. DH-domain.
IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR013098. Ig_I-set.
IPR003598. Ig_sub2.
IPR020682. Obscurin-myosin_light-ch_kin.
IPR001849. PH_domain.
IPR011993. PH_like_dom.
[Graphical view]
PANTHERiPTHR19897:SF17. PTHR19897:SF17. 1 hit.
PfamiPF07679. I-set. 2 hits.
PF00621. RhoGEF. 1 hit.
[Graphical view]
SMARTiSM00408. IGc2. 2 hits.
SM00233. PH. 1 hit.
[Graphical view]
SUPFAMiSSF48065. SSF48065. 1 hit.
PROSITEiPS50010. DH_2. 1 hit.
PS50835. IG_LIKE. 2 hits.
PS50003. PH_DOMAIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q80ZF5-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
GTSKDPTQPP PPPLQHYLEQ PVERVQKYQA LLKELIRNKA RNRQNCALLE
60 70 80 90 100
QAYAVVSALP QRAENKLHVS LMENYPGTLE ALGEPIRQGH FIVWEGAPGA
110 120 130 140 150
RMPWKGHNRH VFLFRNHLVI CKPRRDSRTD TFSYVFRNMM KLNSIDLNDQ
160 170 180 190 200
VEGDDRAFEV WHEREDSVRK YLLQARTVII KNSWVKEICG IQQRLAQPVW
210 220 230 240 250
CPPEFEEELA DCTAELGETV KLACRVTGTP KPIVSWYKDG KPVEVDPHHI
260 270 280 290 300
LIEDPDGSCT LILDNLTGID SGQYMCFAAS AAGNASTLGK ILVQVPPRFV
310 320 330 340 350
NKVRATPFVE GEDAQITCTV EGAPYPQIRW YKDGALLTLG NRYRMVNEPR
360 370 380 390 400
SGMLVLVIQA ASKEDLGHYE CELVNRLGST RCGGELYMQS PALRAWDQHH
410 420 430 440 450
REQLVAAVEV TEQETKVPKK TVIIEETITT VVKSPRGRRQ SPSKSPSRSP
460 470 480 490 500
SRRSASPRRP GLLAPEMLYP PGTSPSRRLE VEQGRKAPVP ALYVTEAEAH
510 520 530 540 550
TPASQPQPKW LEVEETIEVR VKKTGSRGAS PVREMTSHGE GILFTLPGAI
560 570 580 590 600
PARDPNANNS NNKSVYQGAR TWGPAVVHVG EPFVFQVDSV GNVDWAAAGP
610 620 630 640 650
ESEEVRASQE EENVEKEEGG SDGDENTFLM EEPQDTDSLQ GRDPKILTHN
660 670 680 690 700
GRVLTLADLE DYVPQEGETF GCGDPTPSAP DEPPCEVSVL QREIGELTVG
710 720 730 740 750
QPVLLNVGRP PGPSATPSFF RPSSQVHSPE SVSFLLREAW TGPASAAPWT
760 770 780 790 800
SSFHTHVQSS VDGGHGSFKT EVSTQTVSFG AVGETVTLHI DPDGGEAPGP

SQG
Length:803
Mass (Da):88,463
Last modified:June 1, 2003 - v1
Checksum:iA1BC0789EBF277D6
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY167411 mRNA. Translation: AAO34127.1.
UniGeneiRn.232158.
Rn.40889.

Genome annotation databases

UCSCiRGD:631335. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY167411 mRNA. Translation: AAO34127.1 .
UniGenei Rn.232158.
Rn.40889.

3D structure databases

ProteinModelPortali Q80ZF5.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 10116.ENSRNOP00000029928.

PTM databases

PhosphoSitei Q80ZF5.

Proteomic databases

PaxDbi Q80ZF5.
PRIDEi Q80ZF5.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

UCSCi RGD:631335. rat.

Organism-specific databases

RGDi 631335. Obscn.

Phylogenomic databases

eggNOGi COG0515.
HOGENOMi HOG000202800.
HOVERGENi HBG099610.
PhylomeDBi Q80ZF5.

Gene expression databases

Genevestigatori Q80ZF5.

Family and domain databases

Gene3Di 1.20.900.10. 1 hit.
2.30.29.30. 1 hit.
2.60.40.10. 2 hits.
InterProi IPR000219. DH-domain.
IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR013098. Ig_I-set.
IPR003598. Ig_sub2.
IPR020682. Obscurin-myosin_light-ch_kin.
IPR001849. PH_domain.
IPR011993. PH_like_dom.
[Graphical view ]
PANTHERi PTHR19897:SF17. PTHR19897:SF17. 1 hit.
Pfami PF07679. I-set. 2 hits.
PF00621. RhoGEF. 1 hit.
[Graphical view ]
SMARTi SM00408. IGc2. 2 hits.
SM00233. PH. 1 hit.
[Graphical view ]
SUPFAMi SSF48065. SSF48065. 1 hit.
PROSITEi PS50010. DH_2. 1 hit.
PS50835. IG_LIKE. 2 hits.
PS50003. PH_DOMAIN. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: Sprague-DawleyImported.

Entry informationi

Entry nameiQ80ZF5_RAT
AccessioniPrimary (citable) accession number: Q80ZF5
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: June 1, 2003
Last modified: October 29, 2014
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)