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Protein
Submitted name:

Obscurin

Gene

Obscurin

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  • ankyrin binding Source: BHF-UCL
  • Rho guanyl-nucleotide exchange factor activity Source: InterPro
  • structural constituent of muscle Source: BHF-UCL

GO - Biological processi

  • protein localization to M-band Source: BHF-UCL
  • regulation of Rho protein signal transduction Source: InterPro

Names & Taxonomyi

Protein namesi
Submitted name:
ObscurinImported
Gene namesi
Name:ObscurinImported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

PRIDEiQ80ZF5

Interactioni

GO - Molecular functioni

  • ankyrin binding Source: BHF-UCL
  • Rho guanyl-nucleotide exchange factor activity Source: InterPro

Structurei

3D structure databases

ProteinModelPortaliQ80ZF5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini13 – 66DHInterPro annotationAdd BLAST54
Domaini84 – 193PHInterPro annotationAdd BLAST110
Domaini203 – 286Ig-likeInterPro annotationAdd BLAST84
Domaini297 – 375Ig-likeInterPro annotationAdd BLAST79

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili25 – 52Sequence analysisAdd BLAST28

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG0032 Eukaryota
KOG0613 Eukaryota
ENOG410XQFD LUCA
HOGENOMiHOG000202800
HOVERGENiHBG099610
PhylomeDBiQ80ZF5

Family and domain databases

Gene3Di1.20.900.10, 1 hit
2.30.29.30, 1 hit
2.60.40.10, 2 hits
InterProiView protein in InterPro
IPR035899 DBL_dom_sf
IPR000219 DH-domain
IPR007110 Ig-like_dom
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR013098 Ig_I-set
IPR003599 Ig_sub
IPR003598 Ig_sub2
IPR013106 Ig_V-set
IPR011993 PH-like_dom_sf
IPR001849 PH_domain
PfamiView protein in Pfam
PF07679 I-set, 2 hits
PF00169 PH, 1 hit
PF00621 RhoGEF, 1 hit
SMARTiView protein in SMART
SM00409 IG, 2 hits
SM00408 IGc2, 2 hits
SM00406 IGv, 2 hits
SM00233 PH, 1 hit
SUPFAMiSSF48065 SSF48065, 1 hit
SSF48726 SSF48726, 2 hits
PROSITEiView protein in PROSITE
PS50010 DH_2, 1 hit
PS50835 IG_LIKE, 2 hits
PS50003 PH_DOMAIN, 1 hit

Sequencei

Sequence statusi: Fragment.

Q80ZF5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
GTSKDPTQPP PPPLQHYLEQ PVERVQKYQA LLKELIRNKA RNRQNCALLE
60 70 80 90 100
QAYAVVSALP QRAENKLHVS LMENYPGTLE ALGEPIRQGH FIVWEGAPGA
110 120 130 140 150
RMPWKGHNRH VFLFRNHLVI CKPRRDSRTD TFSYVFRNMM KLNSIDLNDQ
160 170 180 190 200
VEGDDRAFEV WHEREDSVRK YLLQARTVII KNSWVKEICG IQQRLAQPVW
210 220 230 240 250
CPPEFEEELA DCTAELGETV KLACRVTGTP KPIVSWYKDG KPVEVDPHHI
260 270 280 290 300
LIEDPDGSCT LILDNLTGID SGQYMCFAAS AAGNASTLGK ILVQVPPRFV
310 320 330 340 350
NKVRATPFVE GEDAQITCTV EGAPYPQIRW YKDGALLTLG NRYRMVNEPR
360 370 380 390 400
SGMLVLVIQA ASKEDLGHYE CELVNRLGST RCGGELYMQS PALRAWDQHH
410 420 430 440 450
REQLVAAVEV TEQETKVPKK TVIIEETITT VVKSPRGRRQ SPSKSPSRSP
460 470 480 490 500
SRRSASPRRP GLLAPEMLYP PGTSPSRRLE VEQGRKAPVP ALYVTEAEAH
510 520 530 540 550
TPASQPQPKW LEVEETIEVR VKKTGSRGAS PVREMTSHGE GILFTLPGAI
560 570 580 590 600
PARDPNANNS NNKSVYQGAR TWGPAVVHVG EPFVFQVDSV GNVDWAAAGP
610 620 630 640 650
ESEEVRASQE EENVEKEEGG SDGDENTFLM EEPQDTDSLQ GRDPKILTHN
660 670 680 690 700
GRVLTLADLE DYVPQEGETF GCGDPTPSAP DEPPCEVSVL QREIGELTVG
710 720 730 740 750
QPVLLNVGRP PGPSATPSFF RPSSQVHSPE SVSFLLREAW TGPASAAPWT
760 770 780 790 800
SSFHTHVQSS VDGGHGSFKT EVSTQTVSFG AVGETVTLHI DPDGGEAPGP

SQG
Length:803
Mass (Da):88,463
Last modified:June 1, 2003 - v1
Checksum:iA1BC0789EBF277D6
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY167411 mRNA Translation: AAO34127.1
UniGeneiRn.232158
Rn.40889

Genome annotation databases

UCSCiRGD:631335 rat

Similar proteinsi

Entry informationi

Entry nameiQ80ZF5_RAT
AccessioniPrimary (citable) accession number: Q80ZF5
Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: June 1, 2003
Last modified: April 25, 2018
This is version 101 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health