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Protein
Submitted name:

CD2AP/CMS

Gene

Cd2ap

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

Enzyme and pathway databases

ReactomeiR-RNO-373753. Nephrin interactions.

Names & Taxonomyi

Protein namesi
Submitted name:
CD2AP/CMSImported
Gene namesi
Name:Cd2apImported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

Organism-specific databases

RGDi727803. Cd2ap.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Proteomic databases

PaxDbiQ80ZE7.
PRIDEiQ80ZE7.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000016291.

Structurei

3D structure databases

ProteinModelPortaliQ80ZE7.
SMRiQ80ZE7. Positions 1-58, 111-166, 266-329.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini1 – 5959SH3InterPro annotationAdd
BLAST
Domaini108 – 16760SH3InterPro annotationAdd
BLAST
Domaini269 – 33062SH3InterPro annotationAdd
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili581 – 63353Sequence analysisAdd
BLAST

Sequence similaritiesi

Contains 3 SH3 domains.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis, SH3 domainUniRule annotation

Phylogenomic databases

eggNOGiKOG4348. Eukaryota.
ENOG410XQBY. LUCA.
HOVERGENiHBG057824.
KOiK13738.
PhylomeDBiQ80ZE7.

Family and domain databases

InterProiIPR028445. CD2AP.
IPR001452. SH3_domain.
[Graphical view]
PANTHERiPTHR14167:SF23. PTHR14167:SF23. 1 hit.
PfamiPF00018. SH3_1. 1 hit.
PF14604. SH3_9. 2 hits.
[Graphical view]
PRINTSiPR00452. SH3DOMAIN.
SMARTiSM00326. SH3. 3 hits.
[Graphical view]
SUPFAMiSSF50044. SSF50044. 3 hits.
PROSITEiPS50002. SH3. 3 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q80ZE7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVDYIVEYDY GAVHDDELTI RVGEIIRNVK KLQEEGWLEG ELNGRRGMFP
60 70 80 90 100
DNFVKEIKRE TEPKDDNLPI KRERPGNVAS LVQRISTYGL PAGGIQPHPQ
110 120 130 140 150
TKAMKKKTKK RQCKVLFEYS PQNEDELELT VGDVIDVIKE VEEGWWSGTL
160 170 180 190 200
NNKLGLFPSN FVKELESTDD GEMHDAQEES EVSLTGPTSP MPSPGNGSEP
210 220 230 240 250
APGSVTQPKK IRGVGFGDIF EQGSVKLRTR TSSSETEEKK SEKPLILQSL
260 270 280 290 300
GSRTQNVEVT KPDIDGKIKA KEYCKTVFPY TGTNEDELTF REGEIIHLIS
310 320 330 340 350
KETGEAGWWK GELNGKEGVF PDNFAVQISE LDKDFPKPKK PPPPAKGPAP
360 370 380 390 400
KPDPLAGEKK TFPLKAEDRD EKSLLEQKPS KPAAPQVPPK KPTPPTKANN
410 420 430 440 450
LLRSPGTMYP KRPEKPVPPP PPTAKINGEV STISSKIDTE PLSKPKLDPE
460 470 480 490 500
QLPVRPKSVD LDALVARNSK ETDNVNFDDI ASSENLLHLT ANRPKMPGRR
510 520 530 540 550
LPGRFNGGHS PTQSPEKTLK LPKDDDSGNI KPSEFKKDAG YSSKPSLSAP
560 570 580 590 600
SSASKVNTAA FLSPLELKAK VEADDGTKSS LDELRAQITE LLCIVDALKK
610 620 630
DHGKELEKLR RELEEEKAMR SNLEVEIAKL KKAVLLS
Length:637
Mass (Da):70,393
Last modified:June 1, 2003 - v1
Checksum:i225698B6FB72EA23
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY205155 mRNA. Translation: AAO46043.1.
RefSeqiNP_852140.1. NM_181475.2.
UniGeneiRn.212220.
Rn.33933.

Genome annotation databases

GeneIDi316258.
KEGGirno:316258.
UCSCiRGD:727803. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY205155 mRNA. Translation: AAO46043.1.
RefSeqiNP_852140.1. NM_181475.2.
UniGeneiRn.212220.
Rn.33933.

3D structure databases

ProteinModelPortaliQ80ZE7.
SMRiQ80ZE7. Positions 1-58, 111-166, 266-329.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000016291.

Proteomic databases

PaxDbiQ80ZE7.
PRIDEiQ80ZE7.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi316258.
KEGGirno:316258.
UCSCiRGD:727803. rat.

Organism-specific databases

CTDi23607.
RGDi727803. Cd2ap.

Phylogenomic databases

eggNOGiKOG4348. Eukaryota.
ENOG410XQBY. LUCA.
HOVERGENiHBG057824.
KOiK13738.
PhylomeDBiQ80ZE7.

Enzyme and pathway databases

ReactomeiR-RNO-373753. Nephrin interactions.

Family and domain databases

InterProiIPR028445. CD2AP.
IPR001452. SH3_domain.
[Graphical view]
PANTHERiPTHR14167:SF23. PTHR14167:SF23. 1 hit.
PfamiPF00018. SH3_1. 1 hit.
PF14604. SH3_9. 2 hits.
[Graphical view]
PRINTSiPR00452. SH3DOMAIN.
SMARTiSM00326. SH3. 3 hits.
[Graphical view]
SUPFAMiSSF50044. SSF50044. 3 hits.
PROSITEiPS50002. SH3. 3 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ80ZE7_RAT
AccessioniPrimary (citable) accession number: Q80ZE7
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: June 1, 2003
Last modified: June 8, 2016
This is version 92 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.