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Q80ZB2

- Q80ZB2_RAT

UniProt

Q80ZB2 - Q80ZB2_RAT

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Protein
Submitted name: ATP-binding cassette 1
Gene
Abca1
Organism
Rattus norvegicus (Rat)
Status
Unreviewed - Annotation score: 3 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. ATPase activity, coupled to transmembrane movement of substances Source: RGD
Complete GO annotation...

GO - Biological processi

  1. cellular response to cholesterol Source: RGD
  2. cholesterol transport Source: RGD
  3. lipoprotein biosynthetic process Source: RGD
  4. phospholipid transport Source: RGD
  5. response to drug Source: RGD
  6. response to nutrient Source: RGD
  7. transmembrane transport Source: GOC
Complete GO annotation...

Keywords - Ligandi

ATP-bindingUniRule annotationImported, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
ATP-binding cassette 1Imported
Gene namesi
Name:Abca1Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

Organism-specific databases

RGDi631344. Abca1.

Subcellular locationi

GO - Cellular componenti

  1. cell surface Source: RGD
Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiQ80ZB2.

PTM databases

PhosphoSiteiQ80ZB2.

Expressioni

Gene expression databases

GenevestigatoriQ80ZB2.

Structurei

3D structure databases

ProteinModelPortaliQ80ZB2.

Family & Domainsi

Sequence similaritiesi

Belongs to the ABC transporter superfamily.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000231547.
HOVERGENiHBG050436.
InParanoidiQ80ZB2.
KOiK05641.
PhylomeDBiQ80ZB2.

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
InterProiIPR003593. AAA+_ATPase.
IPR026082. ABC_A.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR027417. P-loop_NTPase.
[Graphical view]
PANTHERiPTHR19229. PTHR19229. 1 hit.
PfamiPF00005. ABC_tran. 2 hits.
[Graphical view]
SMARTiSM00382. AAA. 2 hits.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 2 hits.
PROSITEiPS00211. ABC_TRANSPORTER_1. 1 hit.
PS50893. ABC_TRANSPORTER_2. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q80ZB2-1 [UniParc]FASTAAdd to Basket

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MPSAGTLPWV QGIICNANNP CFRYPTPGEA PGVVGNFNKS IVSRLFSDAQ     50
RILLYSQKDT SIRDMHKVLR TLQQIKHPNS NLKLQDFLVD NETFSGFLQH 100
SLSLPRSAVD NLLQADVSLQ KVFLQGYQLH LASLCNGSKL EEIIRPEDLK 150
VSALCSLPRE KLDAPERELR SNMDILKPVM TKLNSTSLLP TQHLAEATTT 200
LLDSLGGLAQ ELFSTKSWSD MRQEVMFLTN VNNSGSSTQI YQAVSRIVCG 250
HPEGGGLKIK SLNWYEDNNY KALFGGNGTE EDTDTFYDNS TTPYCNDLMK 300
NLESSPLSRI IWKALKPLLI GKILYTPDTP ATRQVMAEVN KTFQELALFP 350
DLEGMWEELS PQIWTFMESS QEMDLVRPML DLRGNDQFWE RKLDGLYWTA 400
QDIMAFLAKN PEDVQSPNGS VYTWREAFNE TNQAIQTISR FMECVNLNKL 450
EPIPTEVTLI NKSMDLLDAR KFSAGIDFTG ITPDSVELPH HVKDKIRMDI 500
DNVERTNKIK DGYWDPGPRA DPFEDMRYVW GGFAYLQDVV EQAIIRVLTG 550
TEKKTGVYVQ QMPYPCYVDD IFLRVMSRSM PLFMTLAWIY SVAVIIKSIV 600
YEKEARLKET MRIMGLDNGI LWFSWFISSL IPLLVSAGLL VIILKLGDLL 650
PYSDPSVVFV FLSVFAVVTI LQCFLISTLF SRXNLAAACG GIIYFTLYLP 700
YVLCVAWQDY VGFSIKIFAS LLSPVAFGFG CEYFALFEEQ GIGVQWDNLF 750
KSPVEEDGFN LTTSVSMMLF DTFIYGVMTW YIEAVFPGQY GIPRPWYFPC 800
TKSYWFGEEI DEKSHPGSSQ KGASEICMEE EPTHLKLGVS IQNLVKVYRD 850
GMKVAVDGLA LNFYEGQITS FLGHNGAGKT TTMSILTGLF PPTSGTAYIL 900
GKDIRSEMNS IRQNLGVCPQ HNVLFDMLTV EEHIWFYARL KGLSEKHVKA 950
EMEQMALDVG LPPSKLKSKT SQLSGGMQRK LSVALAFVGG SKVVILDEPT 1000
AGVDPYSRRG IWELLLKYRQ GRTIILSTHH MDEADILGDR IAIISHGKLC 1050
CVGSSLFLKN QLGTGYYLTL VKKDVESSLS SCRNSSSTVS CLKKEDSVSQ 1100
SSSDAGLGSD HESDTLTIDV SAISNLIRKH VSEARLVEDI GHELTYVLPY 1150
EAAKEGAFVE LFHEIDDRLS DLGISSYGIS ETTLEEIFLK VAEESGVDAE 1200
TSDGTLPARR NRRAFGDKQS CLHPFTEDDA VDPNDSDLDP ESRETDLLSG 1250
MDGKGSYQLK GWKLTQQQFV ALLWKRLLIA RRSRKGFFAQ IVLPAVFVCI 1300
ALVFSLIVPP FGKYPNLELQ PWMYNEQYTF VSNDAPEDMG TQELLNALTK 1350
DPGFGTRCME GNPIPNTPCL VGEEDWTTGP VPQTLMDLFQ NGNWTMKNPS 1400
PSCQCSSDKI KKMLPVCPPG AGGLPPPQRK QKTADILQNL TGRNNSDYLV 1450
KTYVQIIAKS LKNKVWVNEF RYGGFSLGVS DSQALPPSQE VNNAIKQMKK 1500
LLKLTKDSSA DRFLSSLGRF MTGLDTKNNV KVWFNNKGWH AISSFLNVIN 1550
NAILRANLQK GENPSQYGIT AFNHPLNLTK QQLSEVALMT TSVDVLVSIC 1600
VIFAMSFVPA SFVVFLIQER VSKAKHLQFI CGVKPVIYWL SNFVWDMCNY 1650
VVPATLVVII FICFQQKSYV SSTNLPVLAL LLLLYGWSIT PLMYPASFVF 1700
KIPSTAYVVL TSVNLFIGIN GSVATFVLEL FTNNKFNDIN DILKSVFLIF 1750
PHFCLGRGLI DMVKNQAMAD ALERFGENRF VSPLSWDLVG RNLFAMAVEG 1800
VVFFLVTVLI QYRFFIRPRP VKARLPPLND EDEDVRRERQ RILEGGGQND 1850
ILEIKELTKI YRRKRKPAVD RICVGIPPGE CFGLLGVNGA GKTSTFKMLT 1900
GDTAVTRGDA LLNKNSILSN IHEVHQNMGY CPQFDAITEL LTGREHLEFF 1950
ALLRGVPEKE VGKVGEWAIR KLGLVKYGEK YASNYSGGNK RKLSTAIALI 2000
GGPPVVFLDE PTTGMDPKAR RFLWNCALSI IKEGRSVVLT SHSMEECEAL 2050
CTRMAIMVNG RFRCLGSVQH LKNRFGDGYT IVVRIAGSNP DLKPVQEFFG 2100
LAFPGSVLKE KHRNMLQYQL PSSLSSLARI FSILSQSKKR LHIEDYSVSQ 2150
TTLDQVFVNF AKDQSDDDHL KDLSLHKNQT VVDVAVLTSF LQDEKVKESY 2200
V 2201
Length:2,201
Mass (Da):246,556
Last modified:June 1, 2003 - v1
Checksum:iB1472978BFC3E6B8
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY208182 mRNA. Translation: AAO53557.1.
RefSeqiNP_835196.1. NM_178095.2.
UniGeneiRn.148916.
Rn.231131.

Genome annotation databases

GeneIDi313210.
KEGGirno:313210.
UCSCiRGD:631344. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY208182 mRNA. Translation: AAO53557.1 .
RefSeqi NP_835196.1. NM_178095.2.
UniGenei Rn.148916.
Rn.231131.

3D structure databases

ProteinModelPortali Q80ZB2.
ModBasei Search...

PTM databases

PhosphoSitei Q80ZB2.

Proteomic databases

PRIDEi Q80ZB2.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 313210.
KEGGi rno:313210.
UCSCi RGD:631344. rat.

Organism-specific databases

CTDi 19.
RGDi 631344. Abca1.

Phylogenomic databases

HOGENOMi HOG000231547.
HOVERGENi HBG050436.
InParanoidi Q80ZB2.
KOi K05641.
PhylomeDBi Q80ZB2.

Miscellaneous databases

NextBioi 665805.
PROi Q80ZB2.

Gene expression databases

Genevestigatori Q80ZB2.

Family and domain databases

Gene3Di 3.40.50.300. 2 hits.
InterProi IPR003593. AAA+_ATPase.
IPR026082. ABC_A.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR027417. P-loop_NTPase.
[Graphical view ]
PANTHERi PTHR19229. PTHR19229. 1 hit.
Pfami PF00005. ABC_tran. 2 hits.
[Graphical view ]
SMARTi SM00382. AAA. 2 hits.
[Graphical view ]
SUPFAMi SSF52540. SSF52540. 2 hits.
PROSITEi PS00211. ABC_TRANSPORTER_1. 1 hit.
PS50893. ABC_TRANSPORTER_2. 2 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Cloning and Characterization of Rat Liver Abca1."
    Ananthanarayanan M., Mirza M.F.
    Submitted (DEC-2002) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: Sprague-DawleyImported.

Entry informationi

Entry nameiQ80ZB2_RAT
AccessioniPrimary (citable) accession number: Q80ZB2
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: June 1, 2003
Last modified: July 9, 2014
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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