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Q80Z94 (Q80Z94_MESAU) Unreviewed, UniProtKB/TrEMBL

Last modified May 29, 2013. Version 42. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Gap junction protein RuleBase RU000630
OrganismMesocricetus auratus (Golden hamster) EMBL AAO61857.1
Taxonomic identifier10036 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Cricetidae › Cricetinae › Mesocricetus

Protein attributes

Sequence length382 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell By similarity. RuleBase RU000630

Subunit structure

A connexon is composed of a hexamer of connexins By similarity. RuleBase RU000630

Subcellular location

Membrane; Multi-pass membrane protein By similarity RuleBase RU000630.

Sequence similarities

Belongs to the connexin family. RuleBase RU000630

Sequences

Sequence LengthMass (Da)Tools
Q80Z94 [UniParc].

Last modified June 1, 2003. Version 1.
Checksum: 988D8D466E8B5339

FASTA38243,030
        10         20         30         40         50         60 
MGDWSALGKL LDKVQAYSTA GGKVWLSVLF IFRILLLGTA VESAWGDEQS AFRCNTQQPG 

        70         80         90        100        110        120 
CENVCYDKSF PISHVRFWVL QIIFVSVPTL LYLAHVFYVM RKEEKLNKKE EELKVAQTDG 

       130        140        150        160        170        180 
ANVDMHLKQI EIKKFKYGIE EHGKVKMRGG LLRTYIISIL FKSVFEVAFL LIQWYIYGFS 

       190        200        210        220        230        240 
LSAVYTCKRD PCPHQVDCFL SRPTEKTIFI IFMLVVSLVS LALNIIELFY VFFKGVKDRV 

       250        260        270        280        290        300 
KGRSDPYHAT TGPLNPSKDC GSPKYAYFNG CSSPTAPLSP MSPPGYKLVT GDRNNSSCRN 

       310        320        330        340        350        360 
YNKQASEQNW ANYSAEQNRM GQAGSTISNS HAQPFDFPDD NQNAKKIAAG HELQPLAIVD 

       370        380 
QRPSSRASSR ASSRPRPDDL EI

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References

[1]"The detection of hamster connexins: a comparison of expression profiles with wild-type mouse and the cancer-prone Min mouse."
Cruciani V., Heintz K.M., Husoy T., Hovig E., Warren D.J., Mikalsen S.O.
Cell Commun. Adhes. 11:155-171(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AY206455 mRNA. Translation: AAO61857.1.

3D structure databases

ProteinModelPortalQ80Z94.
SMRQ80Z94. Positions 252-382.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Phylogenomic databases

HOVERGENHBG009576.

Family and domain databases

InterProIPR000500. Connexin.
IPR002261. Connexin43.
IPR013124. Connexin43_C.
IPR019570. Connexin_CCC.
IPR017990. Connexin_CS.
IPR013092. Connexin_N.
[Graphical view]
PANTHERPTHR11984. PTHR11984. 1 hit.
PfamPF00029. Connexin. 1 hit.
PF03508. Connexin43. 1 hit.
PF10582. Connexin_CCC. 1 hit.
[Graphical view]
PRINTSPR00206. CONNEXIN.
PR01132. CONNEXINA1.
SMARTSM00037. CNX. 1 hit.
SM01089. Connexin_CCC. 1 hit.
[Graphical view]
PROSITEPS00407. CONNEXINS_1. 1 hit.
PS00408. CONNEXINS_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ80Z94_MESAU
AccessionPrimary (citable) accession number: Q80Z94
Entry history
Integrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: June 1, 2003
Last modified: May 29, 2013
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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