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Q80Z68 (Q80Z68_MOUSE) Unreviewed, UniProtKB/TrEMBL

Last modified February 19, 2014. Version 99. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein names

Rho GTPase activating protein 4, isoform CRA_f EMBL EDL29866.1

Rho GTPase-activating protein p115 splice form 1 EMBL AAO66338.1
Gene names
Name:Arhgap4 Ensembl ENSMUSP00000067477 MGI 2159577 EMBL EDL29866.1
ORF Names:mCG_140218 EMBL EDL29866.1
OrganismMus musculus (Mouse) [Reference proteome]
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Protein attributes

Sequence length955 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Sequence similarities

Contains FCH domain. SAAS SAAS001060

Sequences

Sequence LengthMass (Da)Tools
Q80Z68 [UniParc].

Last modified June 1, 2003. Version 1.
Checksum: 3443807926C15D60

FASTA955106,451
        10         20         30         40         50         60 
MAAHGKLRRE RGLQPEYDAQ VKEMRWQLSE QLHCLELQGE LRRDLLQELA EFMRRRAEVE 

        70         80         90        100        110        120 
LEYSRGLDKL AERFTSRSGR LGGSSQEQQS FRKEPTLLSP LHCWAVLLEH TRQQSRESAA 

       130        140        150        160        170        180 
LSEVLAGPLA QRLSHISEDV GRIVKKSKDL VQQLQAELLE VVSELQTTKK MYHVYHSESM 

       190        200        210        220        230        240 
NAETKLREAE RQEEKRSGRS ALSTTTTTSA TTTTTTTTVE TGPHRKSSLK KGGRLVEKRQ 

       250        260        270        280        290        300 
AKYLEHKLKC TKARNEYLLS LASVNAAISN YYLHDILDLM DCCDTGFHLA LEQALRSYTA 

       310        320        330        340        350        360 
AESRTQTSQM QGLGSLEEAL EALDPPGDKA KVLEVHAMAF CPPLRFEYQP HEDDEVAEVL 

       370        380        390        400        410        420 
IEMELWDEIL PRAQNIQSRL DQKTIETEEV NKTLKATLKA LLEAVASEDG DILDSLQASP 

       430        440        450        460        470        480 
STESLKSTSS DPGTRQTGRR RNQQQETETF YITKLQEYLS GRSILSKLQA KHEKLQEAIQ 

       490        500        510        520        530        540 
QGNKEKQETS RTQCTERKFH KSHPPHPRFQ YNQRLFGGDL EKFIQSSGQP VPLVVESCIR 

       550        560        570        580        590        600 
FINLNGLQHE GIFRVSGAQA RISEIRDAFE RGEDPLEKGC TVHDLDSVAG VLKLYFRSLE 

       610        620        630        640        650        660 
PPLFPLDMFN ELLASAELEV VGERVEPVSH LLFKLPRPVL VVLRYLFTFL NHLAQYSDEN 

       670        680        690        700        710        720 
MMDSYNLAVC FGPTLLPVPA GQDPVALQGR VNQLVQTLIL QPARIFPPPA MLPGPIYEKC 

       730        740        750        760        770        780 
MAPPSASCLG DGQLESLIGE PELELKTGTT AQEDDQEGVL EAVACFAYTG RTAQELTFQR 

       790        800        810        820        830        840 
GDVLRLYARA SSDWWRGEHA GVQGLIPHKY ITLCEGDEKQ MAGSGLQAMG ESVSHPEGFL 

       850        860        870        880        890        900 
TLEFANRLEL GTPPEALGPS RHRRPCLVPT SPEGHVEMDK AVAQNMNSVF KELLGKTAVR 

       910        920        930        940        950 
QGHGLASTAS PSLGTLTPLA CSSISKNKVF SRGPGAPISP STSHPQGPDS TRKPV 

« Hide

References

« Hide 'large scale' references
[1]"High-efficiency full-length cDNA cloning."
Carninci P., Hayashizaki Y.
Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: NOD EMBL BAE34037.1.
Tissue: Activated spleen EMBL BAE34037.1.
[2]"Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: NOD EMBL BAE34037.1.
Tissue: Activated spleen EMBL BAE34037.1.
[3]"RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer."
Shibata K., Itoh M., Aizawa K., Nagaoka S., Sasaki N., Carninci P., Konno H., Akiyama J., Nishi K., Kitsunai T., Tashiro H., Itoh M., Sumi N., Ishii Y., Nakamura S., Hazama M., Nishine T., Harada A. expand/collapse author list , Yamamoto R., Matsumoto H., Sakaguchi S., Ikegami T., Kashiwagi K., Fujiwake S., Inoue K., Togawa Y., Izawa M., Ohara E., Watahiki M., Yoneda Y., Ishikawa T., Ozawa K., Tanaka T., Matsuura S., Kawai J., Okazaki Y., Muramatsu M., Inoue Y., Kira A., Hayashizaki Y.
Genome Res. 10:1757-1771(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: NOD EMBL BAE34037.1.
Tissue: Activated spleen EMBL BAE34037.1.
[4]"Functional annotation of a full-length mouse cDNA collection."
The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
Nature 409:685-690(2001)
Cited for: NUCLEOTIDE SEQUENCE.
Strain: NOD EMBL BAE34037.1.
Tissue: Activated spleen EMBL BAE34037.1.
[5]"Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
Nature 420:563-573(2002)
Cited for: NUCLEOTIDE SEQUENCE.
Strain: NOD EMBL BAE34037.1.
Tissue: Activated spleen EMBL BAE34037.1.
[6]"A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome."
Mural R.J., Adams M.D., Myers E.W., Smith H.O., Miklos G.L., Wides R., Halpern A., Li P.W., Sutton G.G., Nadeau J., Salzberg S.L., Holt R.A., Kodira C.D., Lu F., Chen L., Deng Z., Evangelista C.C., Gan W. expand/collapse author list , Heiman T.J., Li J., Li Z., Merkulov G.V., Milshina N.V., Naik A.K., Qi R., Shue B.C., Wang A., Wang J., Wang X., Yan X., Ye J., Yooseph S., Zhao Q., Zheng L., Zhu S.C., Biddick K., Bolanos R., Delcher A.L., Dew I.M., Fasulo D., Flanigan M.J., Huson D.H., Kravitz S.A., Miller J.R., Mobarry C.M., Reinert K., Remington K.A., Zhang Q., Zheng X.H., Nusskern D.R., Lai Z., Lei Y., Zhong W., Yao A., Guan P., Ji R.R., Gu Z., Wang Z.Y., Zhong F., Xiao C., Chiang C.C., Yandell M., Wortman J.R., Amanatides P.G., Hladun S.L., Pratts E.C., Johnson J.E., Dodson K.L., Woodford K.J., Evans C.A., Gropman B., Rusch D.B., Venter E., Wang M., Smith T.J., Houck J.T., Tompkins D.E., Haynes C., Jacob D., Chin S.H., Allen D.R., Dahlke C.E., Sanders R., Li K., Liu X., Levitsky A.A., Majoros W.H., Chen Q., Xia A.C., Lopez J.R., Donnelly M.T., Newman M.H., Glodek A., Kraft C.L., Nodell M., Ali F., An H.J., Baldwin-Pitts D., Beeson K.Y., Cai S., Carnes M., Carver A., Caulk P.M., Center A., Chen Y.H., Cheng M.L., Coyne M.D., Crowder M., Danaher S., Davenport L.B., Desilets R., Dietz S.M., Doup L., Dullaghan P., Ferriera S., Fosler C.R., Gire H.C., Gluecksmann A., Gocayne J.D., Gray J., Hart B., Haynes J., Hoover J., Howland T., Ibegwam C., Jalali M., Johns D., Kline L., Ma D.S., MacCawley S., Magoon A., Mann F., May D., McIntosh T.C., Mehta S., Moy L., Moy M.C., Murphy B.J., Murphy S.D., Nelson K.A., Nuri Z., Parker K.A., Prudhomme A.C., Puri V.N., Qureshi H., Raley J.C., Reardon M.S., Regier M.A., Rogers Y.H., Romblad D.L., Schutz J., Scott J.L., Scott R., Sitter C.D., Smallwood M., Sprague A.C., Stewart E., Strong R.V., Suh E., Sylvester K., Thomas R., Tint N.N., Tsonis C., Wang G., Wang G., Williams M.S., Williams S.M., Windsor S.M., Wolfe K., Wu M.M., Zaveri J., Chaturvedi K., Gabrielian A.E., Ke Z., Sun J., Subramanian G., Venter J.C., Pfannkoch C.M., Barnstead M., Stephenson L.D.
Science 296:1661-1671(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: Mixed EMBL EDL29866.1.
[7]"ARHGAP4/Arhgap4 transcripts in human and mouse."
Reichwald K., Petz U., Rosenthal A., Platzer M.
Submitted (NOV-2002) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: BALB/c EMBL AAO66338.1.
[8]Arakawa T., Carninci P., Fukuda S., Hashizume W., Hayashida K., Hori F., Iida J., Imamura K., Imotani K., Itoh M., Kanagawa S., Kawai J., Kojima M., Konno H., Murata M., Nakamura M., Ninomiya N., Nishiyori H. expand/collapse author list , Nomura K., Ohno M., Sakazume N., Sano H., Sasaki D., Shibata K., Shiraki T., Tagami M., Tagami Y., Waki K., Watahiki A., Muramatsu M., Hayashizaki Y.
Submitted (MAR-2004) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: NOD EMBL BAE34037.1.
Tissue: Activated spleen EMBL BAE34037.1.
[9]"The Transcriptional Landscape of the Mammalian Genome."
The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
Science 309:1559-1563(2005)
Cited for: NUCLEOTIDE SEQUENCE.
Strain: NOD EMBL BAE34037.1.
Tissue: Activated spleen EMBL BAE34037.1.
[10]"Antisense Transcription in the Mammalian Transcriptome."
RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group) and the FANTOM Consortium
Science 309:1564-1566(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: NOD EMBL BAE34037.1.
Tissue: Activated spleen EMBL BAE34037.1.
[11]Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.
Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: Mixed EMBL EDL29866.1.
[12]"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. expand/collapse author list , Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P.
PLoS Biol. 7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: C57BL/6J Ensembl ENSMUSP00000067477.
[13]Ensembl
Submitted (FEB-2012) to UniProtKB
Cited for: IDENTIFICATION.
Strain: C57BL/6J Ensembl ENSMUSP00000067477.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AL672002 Genomic DNA. No translation available.
AY183124 mRNA. Translation: AAO66338.1.
AK157294 mRNA. Translation: BAE34037.1.
CH466650 Genomic DNA. Translation: EDL29866.1.
RefSeqNP_619536.2. NM_138630.2.
UniGeneMm.482337.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSMUST00000064376; ENSMUSP00000067477; ENSMUSG00000031389.
GeneID171207.
KEGGmmu:171207.
UCSCuc009tna.2. mouse.

Organism-specific databases

CTD393.
MGIMGI:2159577. Arhgap4.

Phylogenomic databases

GeneTreeENSGT00710000106292.
HOGENOMHOG000039980.
HOVERGENHBG051637.
TreeFamTF315892.

Gene expression databases

GenevestigatorQ80Z68.

Family and domain databases

Gene3D1.10.555.10. 1 hit.
InterProIPR001060. FCH_dom.
IPR008936. Rho_GTPase_activation_prot.
IPR000198. RhoGAP_dom.
IPR011511. SH3_2.
IPR001452. SH3_domain.
[Graphical view]
PfamPF00611. FCH. 1 hit.
PF00620. RhoGAP. 1 hit.
PF07653. SH3_2. 1 hit.
[Graphical view]
SMARTSM00055. FCH. 1 hit.
SM00324. RhoGAP. 1 hit.
SM00326. SH3. 1 hit.
[Graphical view]
SUPFAMSSF48350. SSF48350. 1 hit.
SSF50044. SSF50044. 1 hit.
PROSITEPS50133. FCH. 1 hit.
PS50238. RHOGAP. 1 hit.
PS50002. SH3. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

ChiTaRSARHGAP4. mouse.
NextBio370690.
SOURCESearch...

Entry information

Entry nameQ80Z68_MOUSE
AccessionPrimary (citable) accession number: Q80Z68
Entry history
Integrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: June 1, 2003
Last modified: February 19, 2014
This is version 99 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)