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Q80YN3

- BCAS1_MOUSE

UniProt

Q80YN3 - BCAS1_MOUSE

Protein

Breast carcinoma-amplified sequence 1 homolog

Gene

Bcas1

Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 71 (01 Oct 2014)
      Sequence version 3 (27 Jul 2011)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. protein homodimerization activity Source: MGI

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Breast carcinoma-amplified sequence 1 homolog
    Alternative name(s):
    Novel amplified in breast cancer 1 homolog
    Gene namesi
    Name:Bcas1
    Synonyms:Nabc1
    OrganismiMus musculus (Mouse)
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 2

    Organism-specific databases

    MGIiMGI:1924210. Bcas1.

    Subcellular locationi

    Cytoplasm By similarity

    GO - Cellular componenti

    1. cytosol Source: MGI

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 633633Breast carcinoma-amplified sequence 1 homologPRO_0000235984Add
    BLAST

    Proteomic databases

    MaxQBiQ80YN3.
    PaxDbiQ80YN3.
    PRIDEiQ80YN3.

    PTM databases

    PhosphoSiteiQ80YN3.

    Expressioni

    Gene expression databases

    BgeeiQ80YN3.
    CleanExiMM_BCAS1.
    GenevestigatoriQ80YN3.

    Interactioni

    Subunit structurei

    Homodimer. May interact with DYNLL1 and DYNLL2 By similarity.By similarity

    Protein-protein interaction databases

    BioGridi218429. 2 interactions.
    IntActiQ80YN3. 2 interactions.
    MINTiMINT-4125396.

    Structurei

    3D structure databases

    ProteinModelPortaliQ80YN3.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    eggNOGiNOG40594.
    GeneTreeiENSGT00390000003167.
    HOGENOMiHOG000232037.
    HOVERGENiHBG082347.
    InParanoidiA2AVX2.
    OMAiTQGAAKN.
    TreeFamiTF335555.

    Family and domain databases

    InterProiIPR026115. NABC1.
    [Graphical view]
    PANTHERiPTHR15016. PTHR15016. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q80YN3-1 [UniParc]FASTAAdd to Basket

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    MGNQMSVPLR PGDQEHDPGA DTCKVTSDNE CVQNGNPVVL STRVIQHYEE    50
    VDLGISSSKD NVATSSPKTM EAQAVGDASG KNLGKEAKTK APAARSHFFL 100
    TLSRPVPGRP GDQGTDSSAA SGRFDVSPSA APENKDPSEH GALPVAAAPG 150
    QAPDKTPGCP EAKQQTLPAT GPLAPSPPES QAEAPAQDKD FGFLNRFFKL 200
    DKGRESAPVN SQPKEAKGSE DPEQATEAPA VPGNPHGVSA GEDIVDSEQR 250
    GQDVDTLSYS VPGDPEVPGT TKEDPQVVDT TENSSSIMSF FKTLVSPNKT 300
    ETKKDPEDTK ATKADSVCDG HAAGQKMSET QAKSKKKRLD SPRLGLSFRK 350
    LFRHKDTENS PTTSANLKSD KANFTPQETR GKTKATKSCS PPPPPPEPTS 400
    EGRDSGKEKA GPTSLPLGKL FWKKSVKEDT LSTGAEENAV CESPVETVRL 450
    EEVESSLQTV DLSEETQPEP TDVKVKEESK PRKTPLMAFL RQMSVRSSEG 500
    IPRSEESNVK DSSCQTSNSV EKTPSPPEPE PAGTAQKNKE TSSSKDKKSV 550
    DKKSATENSK QKNGKQEVRE PAPCVQPPTV EANAMQTGDK TPKKSEKRRQ 600
    SLGGFLKGLG PKRMSDAQVQ TDPVSIGPVG KSK 633
    Length:633
    Mass (Da):67,378
    Last modified:July 27, 2011 - v3
    Checksum:i53DBECB3581A245D
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti122 – 1221G → E in AAO88011. (PubMed:14567997)Curated
    Sequence conflicti164 – 1641Q → E in BAB25989. (PubMed:16141072)Curated
    Sequence conflicti354 – 3541H → R in AAO88011. (PubMed:14567997)Curated
    Sequence conflicti396 – 3961P → S in AAO88011. (PubMed:14567997)Curated
    Sequence conflicti414 – 4141S → L in AAO88011. (PubMed:14567997)Curated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY219233 mRNA. Translation: AAO88011.1.
    AL928812, AL935134 Genomic DNA. Translation: CAM20736.1.
    AL935134, AL928812 Genomic DNA. Translation: CAM20748.1.
    AK008957 mRNA. Translation: BAB25989.1.
    CCDSiCCDS17121.1.
    RefSeqiNP_084091.2. NM_029815.2.
    UniGeneiMm.240850.

    Genome annotation databases

    EnsembliENSMUST00000013667; ENSMUSP00000013667; ENSMUSG00000013523.
    GeneIDi76960.
    KEGGimmu:76960.
    UCSCiuc008obx.2. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY219233 mRNA. Translation: AAO88011.1 .
    AL928812 , AL935134 Genomic DNA. Translation: CAM20736.1 .
    AL935134 , AL928812 Genomic DNA. Translation: CAM20748.1 .
    AK008957 mRNA. Translation: BAB25989.1 .
    CCDSi CCDS17121.1.
    RefSeqi NP_084091.2. NM_029815.2.
    UniGenei Mm.240850.

    3D structure databases

    ProteinModelPortali Q80YN3.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 218429. 2 interactions.
    IntActi Q80YN3. 2 interactions.
    MINTi MINT-4125396.

    PTM databases

    PhosphoSitei Q80YN3.

    Proteomic databases

    MaxQBi Q80YN3.
    PaxDbi Q80YN3.
    PRIDEi Q80YN3.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000013667 ; ENSMUSP00000013667 ; ENSMUSG00000013523 .
    GeneIDi 76960.
    KEGGi mmu:76960.
    UCSCi uc008obx.2. mouse.

    Organism-specific databases

    CTDi 8537.
    MGIi MGI:1924210. Bcas1.

    Phylogenomic databases

    eggNOGi NOG40594.
    GeneTreei ENSGT00390000003167.
    HOGENOMi HOG000232037.
    HOVERGENi HBG082347.
    InParanoidi A2AVX2.
    OMAi TQGAAKN.
    TreeFami TF335555.

    Miscellaneous databases

    NextBioi 346183.
    PROi Q80YN3.
    SOURCEi Search...

    Gene expression databases

    Bgeei Q80YN3.
    CleanExi MM_BCAS1.
    Genevestigatori Q80YN3.

    Family and domain databases

    InterProi IPR026115. NABC1.
    [Graphical view ]
    PANTHERi PTHR15016. PTHR15016. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Characterization of the novel amplified in breast cancer-1 (NABC1) gene product."
      Beardsley D.I., Kowbel D., Lataxes T.A., Mannino J.M., Xin H., Kim W.-J., Collins C., Brown K.D.
      Exp. Cell Res. 290:402-413(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6J.
    3. "The transcriptional landscape of the mammalian genome."
      Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
      , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
      Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 164-633.
      Strain: C57BL/6J.
      Tissue: Stomach.

    Entry informationi

    Entry nameiBCAS1_MOUSE
    AccessioniPrimary (citable) accession number: Q80YN3
    Secondary accession number(s): A2AVX2, Q9CVA1
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 16, 2006
    Last sequence update: July 27, 2011
    Last modified: October 1, 2014
    This is version 71 of the entry and version 3 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. MGD cross-references
      Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot

    External Data

    Dasty 3