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Q80YN3 (BCAS1_MOUSE) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 68. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Breast carcinoma-amplified sequence 1 homolog
Alternative name(s):
Novel amplified in breast cancer 1 homolog
Gene names
Name:Bcas1
Synonyms:Nabc1
OrganismMus musculus (Mouse) [Reference proteome]
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Protein attributes

Sequence length633 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Subunit structure

Homodimer. May interact with DYNLL1 and DYNLL2 By similarity.

Subcellular location

Cytoplasm By similarity.

Ontologies

Keywords
   Cellular componentCytoplasm
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentcytosol

Inferred from sequence orthology Ref.1. Source: MGI

   Molecular_functionprotein homodimerization activity

Inferred from sequence orthology Ref.1. Source: MGI

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 633633Breast carcinoma-amplified sequence 1 homolog
PRO_0000235984

Experimental info

Sequence conflict1221G → E in AAO88011. Ref.1
Sequence conflict1641Q → E in BAB25989. Ref.3
Sequence conflict3541H → R in AAO88011. Ref.1
Sequence conflict3961P → S in AAO88011. Ref.1
Sequence conflict4141S → L in AAO88011. Ref.1

Sequences

Sequence LengthMass (Da)Tools
Q80YN3 [UniParc].

Last modified July 27, 2011. Version 3.
Checksum: 53DBECB3581A245D

FASTA63367,378
        10         20         30         40         50         60 
MGNQMSVPLR PGDQEHDPGA DTCKVTSDNE CVQNGNPVVL STRVIQHYEE VDLGISSSKD 

        70         80         90        100        110        120 
NVATSSPKTM EAQAVGDASG KNLGKEAKTK APAARSHFFL TLSRPVPGRP GDQGTDSSAA 

       130        140        150        160        170        180 
SGRFDVSPSA APENKDPSEH GALPVAAAPG QAPDKTPGCP EAKQQTLPAT GPLAPSPPES 

       190        200        210        220        230        240 
QAEAPAQDKD FGFLNRFFKL DKGRESAPVN SQPKEAKGSE DPEQATEAPA VPGNPHGVSA 

       250        260        270        280        290        300 
GEDIVDSEQR GQDVDTLSYS VPGDPEVPGT TKEDPQVVDT TENSSSIMSF FKTLVSPNKT 

       310        320        330        340        350        360 
ETKKDPEDTK ATKADSVCDG HAAGQKMSET QAKSKKKRLD SPRLGLSFRK LFRHKDTENS 

       370        380        390        400        410        420 
PTTSANLKSD KANFTPQETR GKTKATKSCS PPPPPPEPTS EGRDSGKEKA GPTSLPLGKL 

       430        440        450        460        470        480 
FWKKSVKEDT LSTGAEENAV CESPVETVRL EEVESSLQTV DLSEETQPEP TDVKVKEESK 

       490        500        510        520        530        540 
PRKTPLMAFL RQMSVRSSEG IPRSEESNVK DSSCQTSNSV EKTPSPPEPE PAGTAQKNKE 

       550        560        570        580        590        600 
TSSSKDKKSV DKKSATENSK QKNGKQEVRE PAPCVQPPTV EANAMQTGDK TPKKSEKRRQ 

       610        620        630 
SLGGFLKGLG PKRMSDAQVQ TDPVSIGPVG KSK 

« Hide

References

« Hide 'large scale' references
[1]"Characterization of the novel amplified in breast cancer-1 (NABC1) gene product."
Beardsley D.I., Kowbel D., Lataxes T.A., Mannino J.M., Xin H., Kim W.-J., Collins C., Brown K.D.
Exp. Cell Res. 290:402-413(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
[2]"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. expand/collapse author list , Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P.
PLoS Biol. 7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: C57BL/6J.
[3]"The transcriptional landscape of the mammalian genome."
Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J. expand/collapse author list , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 164-633.
Strain: C57BL/6J.
Tissue: Stomach.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AY219233 mRNA. Translation: AAO88011.1.
AL928812, AL935134 Genomic DNA. Translation: CAM20736.1.
AL935134, AL928812 Genomic DNA. Translation: CAM20748.1.
AK008957 mRNA. Translation: BAB25989.1.
RefSeqNP_084091.2. NM_029815.2.
UniGeneMm.240850.

3D structure databases

ProteinModelPortalQ80YN3.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid218429. 2 interactions.
IntActQ80YN3. 2 interactions.
MINTMINT-4125396.

PTM databases

PhosphoSiteQ80YN3.

Proteomic databases

PaxDbQ80YN3.
PRIDEQ80YN3.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSMUST00000013667; ENSMUSP00000013667; ENSMUSG00000013523.
GeneID76960.
KEGGmmu:76960.
UCSCuc008obx.2. mouse.

Organism-specific databases

CTD8537.
MGIMGI:1924210. Bcas1.

Phylogenomic databases

eggNOGNOG40594.
GeneTreeENSGT00390000003167.
HOGENOMHOG000232037.
HOVERGENHBG082347.
InParanoidA2AVX2.
OMATQGAAKN.
TreeFamTF335555.

Gene expression databases

BgeeQ80YN3.
CleanExMM_BCAS1.
GenevestigatorQ80YN3.

Family and domain databases

InterProIPR026115. NABC1.
[Graphical view]
PANTHERPTHR15016. PTHR15016. 1 hit.
ProtoNetSearch...

Other

NextBio346183.
PROQ80YN3.
SOURCESearch...

Entry information

Entry nameBCAS1_MOUSE
AccessionPrimary (citable) accession number: Q80YN3
Secondary accession number(s): A2AVX2, Q9CVA1
Entry history
Integrated into UniProtKB/Swiss-Prot: May 16, 2006
Last sequence update: July 27, 2011
Last modified: April 16, 2014
This is version 68 of the entry and version 3 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

MGD cross-references

Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot