Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Phosphoserine aminotransferase

Gene
N/A
Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Catalytic activityi

O-phospho-L-serine + 2-oxoglutarate = 3-phosphonooxypyruvate + L-glutamate.UniRule annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotation

Pathwayi: L-serine biosynthesis

This protein is involved in step 2 of the subpathway that synthesizes L-serine from 3-phospho-D-glycerate.UniRule annotation
Proteins known to be involved in the 3 steps of the subpathway in this organism are:
  1. D-3-phosphoglycerate dehydrogenase (Phgdh)
  2. Phosphoserine aminotransferase (Psat1), Phosphoserine aminotransferase (Psat1), Phosphoserine aminotransferase (Psat1), Phosphoserine aminotransferase
  3. Phosphoserine phosphatase (Psph)
This subpathway is part of the pathway L-serine biosynthesis, which is itself part of Amino-acid biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes L-serine from 3-phospho-D-glycerate, the pathway L-serine biosynthesis and in Amino-acid biosynthesis.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminotransferaseUniRule annotationImported, Transferase
Biological processAmino-acid biosynthesis, Serine biosynthesisUniRule annotation

Enzyme and pathway databases

UniPathwayiUPA00135; UER00197

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoserine aminotransferaseUniRule annotation (EC:2.6.1.52UniRule annotation)
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus

PTM / Processingi

Proteomic databases

PRIDEiQ80YG1

Structurei

3D structure databases

ProteinModelPortaliQ80YG1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini225 – 302Ig-likeInterPro annotationAdd BLAST78

Sequence similaritiesi

Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.UniRule annotation

Phylogenomic databases

eggNOGiKOG2790 Eukaryota
COG1932 LUCA
HOVERGENiHBG001218
PhylomeDBiQ80YG1

Family and domain databases

CDDicd00611 PSAT_like, 1 hit
Gene3Di3.40.640.10, 1 hit
3.90.1150.10, 1 hit
HAMAPiMF_00160 SerC_aminotrans_5, 1 hit
InterProiView protein in InterPro
IPR000192 Aminotrans_V_dom
IPR020578 Aminotrans_V_PyrdxlP_BS
IPR007110 Ig-like_dom
IPR022278 Pser_aminoTfrase
IPR015424 PyrdxlP-dep_Trfase
IPR015422 PyrdxlP-dep_Trfase_dom1
IPR015421 PyrdxlP-dep_Trfase_major
PfamiView protein in Pfam
PF00266 Aminotran_5, 1 hit
PIRSFiPIRSF000525 SerC, 1 hit
SUPFAMiSSF53383 SSF53383, 1 hit
TIGRFAMsiTIGR01364 serC_1, 1 hit
PROSITEiView protein in PROSITE
PS00595 AA_TRANSFER_CLASS_5, 1 hit
PS50835 IG_LIKE, 1 hit

Sequencei

Sequence statusi: Complete.

Q80YG1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEATKQVVNF GPGPAKLPYS VLLEIQKQLL DYKGLGISVL EMSHRSPDFA
60 70 80 90 100
KIISNTENLV RELLAVPNNY KVIFVQGGGT GQFSAVPLNL IGLKAGRCAD
110 120 130 140 150
YVVTGAWSAK AAEEARKFGT VNIVHPKLGS YTKIPDPSTW NLNPDASYVY
160 170 180 190 200
FCANETVHGV EFDFIPDVKG AMLVCDMSSN FLSRPVDVSK FGVIFAGAQK
210 220 230 240 250
NVGSAGVTVV IVRDDLLGFA LRECPSVLDY KVQAGNNSLY NTPPCFSTYV
260 270 280 290 300
MGMVLEWIKN NGGAAAMEKL SSVKSQMIYE IIDNSQGFYV CPVERQNRSR
310 320 330 340 350
MNIPFRIGNS KGDEALEKRF LDKAVELNMI SLKGHRSVGG IRASLYNAVT
360 370
TEDVEKLAAF MKNFLEMHQL
Length:370
Mass (Da):40,589
Last modified:June 1, 2003 - v1
Checksum:iCD7DE32BAEFB7B15
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY239016 mRNA Translation: AAO89062.1
UniGeneiRn.100813

Genome annotation databases

UCSCiRGD:735170 rat

Similar proteinsi

Entry informationi

Entry nameiQ80YG1_RAT
AccessioniPrimary (citable) accession number: Q80YG1
Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: June 1, 2003
Last modified: April 25, 2018
This is version 104 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health