ID   Q80Y89_MOUSE            Unreviewed;       711 AA.
AC   Q80Y89;
DT   01-JUN-2003, integrated into UniProtKB/TrEMBL.
DT   01-JUN-2003, sequence version 1.
DT   19-JAN-2010, entry version 45.
DE   SubName: Full=Erbb2 protein;
GN   Name=Erbb2;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;
OC   Muroidea; Muridae; Murinae; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=C57BL/6; TISSUE=Brain;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA
RT   project: the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
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DR   EMBL; BC046811; AAH46811.1; -; mRNA.
DR   EMBL; BC053078; AAH53078.1; -; mRNA.
DR   IPI; IPI00626433; -.
DR   UniGene; Mm.290822; -.
DR   UniGene; Mm.406337; -.
DR   HSSP; P06494; 1N8Y.
DR   SMR; Q80Y89; 23-630, 642-685.
DR   STRING; Q80Y89; -.
DR   Ensembl; ENSMUST00000058295; ENSMUSP00000053897; ENSMUSG00000062312; Mus musculus.
DR   MGI; MGI:95410; Erbb2.
DR   HOVERGEN; Q80Y89; -.
DR   InParanoid; Q80Y89; -.
DR   ArrayExpress; Q80Y89; -.
DR   Bgee; Q80Y89; -.
DR   Genevestigator; Q80Y89; -.
DR   GO; GO:0016324; C:apical plasma membrane; IEA:Compara.
DR   GO; GO:0009925; C:basal plasma membrane; IEA:Compara.
DR   GO; GO:0016021; C:integral to membrane; IEA:InterPro.
DR   GO; GO:0043219; C:lateral loop; IEA:Compara.
DR   GO; GO:0045121; C:membrane raft; IEA:Compara.
DR   GO; GO:0005902; C:microvillus; IEA:Compara.
DR   GO; GO:0005634; C:nucleus; IEA:Compara.
DR   GO; GO:0048471; C:perinuclear region of cytoplasm; IEA:Compara.
DR   GO; GO:0045211; C:postsynaptic membrane; IEA:Compara.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0001948; F:glycoprotein binding; IEA:Compara.
DR   GO; GO:0019838; F:growth factor binding; IEA:Compara.
DR   GO; GO:0051879; F:Hsp90 protein binding; IEA:Compara.
DR   GO; GO:0042802; F:identical protein binding; IEA:Compara.
DR   GO; GO:0008022; F:protein C-terminus binding; IEA:Compara.
DR   GO; GO:0046982; F:protein heterodimerization activity; IEA:Compara.
DR   GO; GO:0019903; F:protein phosphatase binding; IEA:Compara.
DR   GO; GO:0004714; F:transmembrane receptor protein tyrosine kin...; IEA:InterPro.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IEA:Compara.
DR   GO; GO:0060209; P:estrus; IEA:Compara.
DR   GO; GO:0010001; P:glial cell differentiation; IEA:Compara.
DR   GO; GO:0001889; P:liver development; IEA:Compara.
DR   GO; GO:0060056; P:mammary gland involution; IEA:Compara.
DR   GO; GO:0043066; P:negative regulation of apoptosis; IEA:Compara.
DR   GO; GO:0018108; P:peptidyl-tyrosine phosphorylation; IEA:InterPro.
DR   GO; GO:0007422; P:peripheral nervous system development; IEA:Compara.
DR   GO; GO:0014065; P:phosphoinositide 3-kinase cascade; IEA:Compara.
DR   GO; GO:0045785; P:positive regulation of cell adhesion; IEA:Compara.
DR   GO; GO:0050679; P:positive regulation of epithelial cell prol...; IEA:Compara.
DR   GO; GO:0043406; P:positive regulation of MAP kinase activity; IEA:Compara.
DR   GO; GO:0043410; P:positive regulation of MAPKKK cascade; IEA:Compara.
DR   GO; GO:0014068; P:positive regulation of phosphoinositide 3-k...; IEA:Compara.
DR   GO; GO:0046579; P:positive regulation of Ras protein signal t...; IEA:Compara.
DR   GO; GO:0046777; P:protein amino acid autophosphorylation; IEA:Compara.
DR   GO; GO:0048678; P:response to axon injury; IEA:Compara.
DR   GO; GO:0042493; P:response to drug; IEA:Compara.
DR   GO; GO:0032570; P:response to progesterone stimulus; IEA:Compara.
DR   GO; GO:0007519; P:skeletal muscle tissue development; IEA:Compara.
DR   GO; GO:0048485; P:sympathetic nervous system development; IEA:Compara.
DR   GO; GO:0043586; P:tongue development; IEA:Compara.
DR   GO; GO:0007169; P:transmembrane receptor protein tyrosine kin...; IEA:InterPro.
DR   GO; GO:0042060; P:wound healing; IEA:Compara.
DR   InterPro; IPR000494; EGF_rcpt_L.
DR   InterPro; IPR006211; Furin-like_Cys-rich_dom.
DR   InterPro; IPR006212; Furin_repeat.
DR   InterPro; IPR009030; Growth_fac_rcpt.
DR   InterPro; IPR020685; Tyr_prot_kinase.
DR   PANTHER; PTHR23256; Tyr_prot_kinase; 1.
DR   Pfam; PF00757; Furin-like; 1.
DR   Pfam; PF01030; Recep_L_domain; 2.
DR   SMART; SM00261; FU; 4.
PE   2: Evidence at transcript level;
SQ   SEQUENCE   711 AA;  78707 MW;  682B188EB0E71318 CRC64;
     MELAAWCRWG FLLALLSPGA AGTQVCTGTD MKLRLPASPE THLDMLRHLY QGCQVVQGNL
     ELTYLPANAS LSFLQDIQEV QGYMLIAHNR VKHVPLQRLR IVRGTQLFED KYALAVLDNR
     DPLDNVTTAA PGRTPEGLRE LQLRSLTEIL KGGVLIRGNP QLCYQDMVLW KDVLRKNNQL
     APVDMDTNRS RACPPCAPTC KDNHCWGESP EDCQILTGTI CTSGCARCKG RLPTDCCHEQ
     CAAGCTGPKH SDCLACLHFN HSGICELHCP ALITYNTDTF ESMLNPEGRY TFGASCVTTC
     PYNYLSTEVG SCTLVCPPNN QEVTAEDGTQ RCEKCSKPCA GVCYGLGMEH LRGARAITSD
     NIQEFAGCKK IFGSLAFLPE SFDGNPSSGV APLKPEHLQV FETLEEITGY LYISAWPESF
     QDLSVFQNLR VIRGRILHDG AYSLTLQGLG IHSLGLRSLR ELGSGLALIH RNTHLCFVNT
     VPWDQLFRNP HQALLHSGNR PEEACGLEGL VCNSLCARGH CWGPGPTQCV NCSQFLRGQE
     CVEECRVWKG LPREYVRGKH CLPCHPECQP QNSSETCYGS EADQCEACAH YKDSSSCVAR
     CPSGVKPDLS YMPIWKYPDE EGICQPCPIN CTHSCVDLDE RGCPAEQRAS PVTFIIATVV
     GVLLFLIIVV VIGILIKRRR QKIRKYTMRR LLQETEVRRA EGLLAPPWLC S
//