Erbb2 protein - Mus musculus (Mouse)

Contribute

Read comments (0) or add your own

Unreviewed, UniProtKB/TrEMBL Q80Y89 (Q80Y89_MOUSE)

Last modified November 3, 2009. Version 42. History...

Clusters with 100%, 90%, 50% identity |

Third-party data |

Customize display

text xml rdf/xml gff fasta

Names and origin · Protein attributes · Ontologies · Sequences · References · Cross-references · Entry information

Names and origin

Protein names

Submitted name:
Erbb2 protein EMBL AAH46811.1

Gene names

Name:

Erbb2 EMBL AAH46811.1

Organism

Mus musculus (Mouse) EMBL AAH46811.1

Taxonomic identifier

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus

Protein attributes

Sequence length	711 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

Ontologies

Gene Ontology (GO)
Biological process	heart development Inferred from mutant phenotype. Source: MGI motor axon guidance Inferred from mutant phenotype. Source: MGI myelination Inferred from mutant phenotype. Source: MGI negative regulation of immature T cell proliferation in the thymus Inferred from mutant phenotype. Source: MGI neuromuscular junction development Inferred from mutant phenotype. Source: MGI peripheral nervous system development Inferred from mutant phenotype. Source: MGI protein amino acid phosphorylation Inferred from electronic annotation. Source: InterPro transmembrane receptor protein tyrosine kinase signaling pathway Inferred from electronic annotation. Source: InterPro
Cellular component	apical plasma membrane Inferred from direct assay. Source: MGI cytoplasm Inferred from direct assay. Source: MGI
Molecular function	ATP binding Inferred from electronic annotation. Source: InterPro transmembrane receptor protein tyrosine kinase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

Sequence

Length

Mass (Da)

Tools

Q80Y89-1 [UniParc].

Last modified June 1, 2003. Version 1.
Checksum: 682B188EB0E71318
Show »

711

78,707

        10         20         30         40         50         60 
MELAAWCRWG FLLALLSPGA AGTQVCTGTD MKLRLPASPE THLDMLRHLY QGCQVVQGNL 

        70         80         90        100        110        120 
ELTYLPANAS LSFLQDIQEV QGYMLIAHNR VKHVPLQRLR IVRGTQLFED KYALAVLDNR 

       130        140        150        160        170        180 
DPLDNVTTAA PGRTPEGLRE LQLRSLTEIL KGGVLIRGNP QLCYQDMVLW KDVLRKNNQL 

       190        200        210        220        230        240 
APVDMDTNRS RACPPCAPTC KDNHCWGESP EDCQILTGTI CTSGCARCKG RLPTDCCHEQ 

       250        260        270        280        290        300 
CAAGCTGPKH SDCLACLHFN HSGICELHCP ALITYNTDTF ESMLNPEGRY TFGASCVTTC 

       310        320        330        340        350        360 
PYNYLSTEVG SCTLVCPPNN QEVTAEDGTQ RCEKCSKPCA GVCYGLGMEH LRGARAITSD 

       370        380        390        400        410        420 
NIQEFAGCKK IFGSLAFLPE SFDGNPSSGV APLKPEHLQV FETLEEITGY LYISAWPESF 

       430        440        450        460        470        480 
QDLSVFQNLR VIRGRILHDG AYSLTLQGLG IHSLGLRSLR ELGSGLALIH RNTHLCFVNT 

       490        500        510        520        530        540 
VPWDQLFRNP HQALLHSGNR PEEACGLEGL VCNSLCARGH CWGPGPTQCV NCSQFLRGQE 

       550        560        570        580        590        600 
CVEECRVWKG LPREYVRGKH CLPCHPECQP QNSSETCYGS EADQCEACAH YKDSSSCVAR 

       610        620        630        640        650        660 
CPSGVKPDLS YMPIWKYPDE EGICQPCPIN CTHSCVDLDE RGCPAEQRAS PVTFIIATVV 

       670        680        690        700        710 
GVLLFLIIVV VIGILIKRRR QKIRKYTMRR LLQETEVRRA EGLLAPPWLC S

References

[1]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: C57BL/6 EMBL AAH46811.1. Tissue: Brain EMBL AAH46811.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
	BC046811 mRNA. Translation: AAH46811.1. BC053078 mRNA. Translation: AAH53078.1.
IPI	IPI00626433.
UniGene	Mm.290822 Mm.406337
3D structure databases
HSSP	HSSP built from PDB template 1N8Y based on UniProtKB P06494.
SMR	Q80Y89. Positions 23-630.
ModBase	Search...
Protein-protein interaction databases
STRING	Q80Y89.
Genome annotation databases
Ensembl	ENSMUST00000058295; ENSMUSP00000053897; ENSMUSG00000062312; Mus musculus. [Genome view]
Organism-specific databases
MGI	MGI:95410. Erbb2.
Phylogenomic databases
HOVERGEN	Q80Y89.
Gene expression databases
ArrayExpress	Q80Y89.
Bgee	Q80Y89.
Genevestigator	Q80Y89.
Family and domain databases
InterPro	IPR000494. EGF_rcpt_L. IPR006211. Furin-like. IPR006212. Furin_repeat. IPR009030. Growth_fac_rcpt. [Graphical view]
Pfam	PF00757. Furin-like. 1 hit. PF01030. Recep_L_domain. 2 hits. [Graphical view]
SMART	SM00261. FU. 4 hits. [Graphical view]
ProtoNet	Search...
Other Resources
SOURCE	Search...

Entry information

Entry name

Q80Y89_MOUSE

Accession

Primary (citable) accession number: Q80Y89

Entry history

Integrated into UniProtKB/TrEMBL:	June 1, 2003
Last sequence update:	June 1, 2003
Last modified:	November 3, 2009
This is version 42 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Names and origin · Protein attributes · Ontologies · Sequences · References · Cross-references · Entry information