Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

DnaJ homolog subfamily B member 13

Gene

Dnajb13

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

May be involved in inhibiting testis spermatogenesis apoptosis.1 Publication

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Chaperone

Names & Taxonomyi

Protein namesi
Recommended name:
DnaJ homolog subfamily B member 13
Alternative name(s):
Testis and spermatogenesis cell-related protein 6
Testis spermatocyte apoptosis-related gene 6 protein
Testis spermatogenesis apoptosis-related gene 3 protein
Testis spermatogenesis apoptosis-related gene 6 protein
Gene namesi
Name:Dnajb13
Synonyms:Tsarg, Tsarg3, Tsarg6
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 7

Organism-specific databases

MGIiMGI:1916637. Dnajb13.

Subcellular locationi

GO - Cellular componenti

  • axoneme Source: MGI
  • cytoplasm Source: MGI
  • motile cilium Source: MGI
  • sperm flagellum Source: MGI
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 316316DnaJ homolog subfamily B member 13PRO_0000071040Add
BLAST

Proteomic databases

MaxQBiQ80Y75.
PaxDbiQ80Y75.
PRIDEiQ80Y75.

2D gel databases

REPRODUCTION-2DPAGEQ80Y75.

PTM databases

PhosphoSiteiQ80Y75.

Expressioni

Tissue specificityi

Specifically expressed in testis.1 Publication

Gene expression databases

BgeeiQ80Y75.
CleanExiMM_DNAJB13.
GenevisibleiQ80Y75. MM.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000059074.

Structurei

3D structure databases

ProteinModelPortaliQ80Y75.
SMRiQ80Y75. Positions 1-132, 134-314.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini4 – 6865JPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 1 J domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG0714. Eukaryota.
COG0484. LUCA.
GeneTreeiENSGT00760000118947.
HOGENOMiHOG000226718.
HOVERGENiHBG066727.
InParanoidiQ80Y75.
KOiK09519.
OMAiDNPFGEF.
OrthoDBiEOG7TF79F.
PhylomeDBiQ80Y75.
TreeFamiTF105141.

Family and domain databases

Gene3Di1.10.287.110. 1 hit.
InterProiIPR002939. DnaJ_C.
IPR001623. DnaJ_domain.
IPR018253. DnaJ_domain_CS.
IPR008971. HSP40/DnaJ_pept-bd.
[Graphical view]
PfamiPF00226. DnaJ. 1 hit.
PF01556. DnaJ_C. 1 hit.
[Graphical view]
PRINTSiPR00625. JDOMAIN.
SMARTiSM00271. DnaJ. 1 hit.
[Graphical view]
SUPFAMiSSF46565. SSF46565. 1 hit.
SSF49493. SSF49493. 2 hits.
PROSITEiPS00636. DNAJ_1. 1 hit.
PS50076. DNAJ_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q80Y75-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGLDYYAVLQ VTRNSEDAQI KKAYRKLALK NHPLKSSEPG APEIFKQIAE
60 70 80 90 100
AYDVLSDPVK RGIYDKFGEE GLKGGIPLEF GSQTPWTTGY VFHGNPDKVF
110 120 130 140 150
HEFFGGDNPF SEFFDAEGND IDLNFGGLWG RGVQKQDPPI ERDLYLSLED
160 170 180 190 200
LFFGCTKKIK ISRRVLNEDR YSSTIKDKIL TIDVRPGWRQ GTRITFEKEG
210 220 230 240 250
DQGPNIIPAD IIFIVKEKLH PRFRREHDNL FFVYPIPLGK ALTCCTVEVK
260 270 280 290 300
TLDDRLLNIP INDIVHPKYF KIVPGEGMPL PENPSKKGDL FIFFDIQFPT
310
RLTPQKKQML RQALLT
Length:316
Mass (Da):36,155
Last modified:June 1, 2003 - v1
Checksum:i38BBC8271A18C9B5
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti133 – 1331V → I in AAN32703 (PubMed:14673507).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF419292 mRNA. Translation: AAN32703.2.
BC048501 mRNA. Translation: AAH48501.1.
CCDSiCCDS21499.1.
RefSeqiNP_705755.2. NM_153527.2.
UniGeneiMm.278554.

Genome annotation databases

EnsembliENSMUST00000207405; ENSMUSP00000147019; ENSMUSG00000030708.
GeneIDi69387.
KEGGimmu:69387.
UCSCiuc009inc.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF419292 mRNA. Translation: AAN32703.2.
BC048501 mRNA. Translation: AAH48501.1.
CCDSiCCDS21499.1.
RefSeqiNP_705755.2. NM_153527.2.
UniGeneiMm.278554.

3D structure databases

ProteinModelPortaliQ80Y75.
SMRiQ80Y75. Positions 1-132, 134-314.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000059074.

PTM databases

PhosphoSiteiQ80Y75.

2D gel databases

REPRODUCTION-2DPAGEQ80Y75.

Proteomic databases

MaxQBiQ80Y75.
PaxDbiQ80Y75.
PRIDEiQ80Y75.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000207405; ENSMUSP00000147019; ENSMUSG00000030708.
GeneIDi69387.
KEGGimmu:69387.
UCSCiuc009inc.1. mouse.

Organism-specific databases

CTDi374407.
MGIiMGI:1916637. Dnajb13.

Phylogenomic databases

eggNOGiKOG0714. Eukaryota.
COG0484. LUCA.
GeneTreeiENSGT00760000118947.
HOGENOMiHOG000226718.
HOVERGENiHBG066727.
InParanoidiQ80Y75.
KOiK09519.
OMAiDNPFGEF.
OrthoDBiEOG7TF79F.
PhylomeDBiQ80Y75.
TreeFamiTF105141.

Miscellaneous databases

NextBioi329309.
PROiQ80Y75.
SOURCEiSearch...

Gene expression databases

BgeeiQ80Y75.
CleanExiMM_DNAJB13.
GenevisibleiQ80Y75. MM.

Family and domain databases

Gene3Di1.10.287.110. 1 hit.
InterProiIPR002939. DnaJ_C.
IPR001623. DnaJ_domain.
IPR018253. DnaJ_domain_CS.
IPR008971. HSP40/DnaJ_pept-bd.
[Graphical view]
PfamiPF00226. DnaJ. 1 hit.
PF01556. DnaJ_C. 1 hit.
[Graphical view]
PRINTSiPR00625. JDOMAIN.
SMARTiSM00271. DnaJ. 1 hit.
[Graphical view]
SUPFAMiSSF46565. SSF46565. 1 hit.
SSF49493. SSF49493. 2 hits.
PROSITEiPS00636. DNAJ_1. 1 hit.
PS50076. DNAJ_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Molecular cloning of TSARG3 gene related to apoptosis in human spermatogenic cells."
    Liu G., Lu G.-X., Fu J.-J., Liu S.-F., Xing X.-W., Li L.
    Zhonghua Yi Xue Yi Chuan Xue Za Zhi 20:107-110(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Strain: C57BL/6J.
  2. "Molecular cloning of mTSARG3 gene related to apoptosis in mouse spermatogenic cells."
    Liu G., Lu G.-X., Fu J.-J., Liu S.-F., Xing X.-W.
    Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao 35:1133-1139(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: SEQUENCE REVISION, FUNCTION, TISSUE SPECIFICITY.
    Strain: C57BL/6J.
    Tissue: Testis.
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Testis.
  4. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Testis.

Entry informationi

Entry nameiDJB13_MOUSE
AccessioniPrimary (citable) accession number: Q80Y75
Secondary accession number(s): Q8CJA2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 10, 2003
Last sequence update: June 1, 2003
Last modified: May 11, 2016
This is version 97 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.