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Protein

DnaJ homolog subfamily B member 13

Gene

Dnajb13

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Plays a role in the formation of the central complex of ciliary and flagellar axonemes.By similarity1 Publication

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChaperone
Biological processCilium biogenesis/degradation

Names & Taxonomyi

Protein namesi
Recommended name:
DnaJ homolog subfamily B member 13
Alternative name(s):
Testis and spermatogenesis cell-related protein 6
Testis spermatocyte apoptosis-related gene 6 protein
Testis spermatogenesis apoptosis-related gene 3 protein
Testis spermatogenesis apoptosis-related gene 6 protein
Gene namesi
Name:Dnajb13
Synonyms:Tsarg, Tsarg3, Tsarg6
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 7

Organism-specific databases

MGIiMGI:1916637 Dnajb13

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cell projection, Cilium, Flagellum

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000710401 – 316DnaJ homolog subfamily B member 13Add BLAST316

Proteomic databases

MaxQBiQ80Y75
PaxDbiQ80Y75
PRIDEiQ80Y75

2D gel databases

REPRODUCTION-2DPAGEiQ80Y75

PTM databases

PhosphoSitePlusiQ80Y75

Expressioni

Tissue specificityi

Expressed in ciliated cell-containing tissues such as testis, brain, lung, ovary and oviduct.3 Publications

Developmental stagei

Expressed during spermiogenesis.1 Publication

Gene expression databases

BgeeiENSMUSG00000030708
CleanExiMM_DNAJB13
ExpressionAtlasiQ80Y75 baseline and differential
GenevisibleiQ80Y75 MM

Interactioni

Subunit structurei

Homodimer (By similarity). Interacts with SUN5 (PubMed:29298896).By similarity1 Publication

GO - Molecular functioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000059074

Structurei

3D structure databases

ProteinModelPortaliQ80Y75
SMRiQ80Y75
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini4 – 68JPROSITE-ProRule annotationAdd BLAST65

Phylogenomic databases

eggNOGiKOG0714 Eukaryota
COG0484 LUCA
GeneTreeiENSGT00760000118947
HOGENOMiHOG000226718
HOVERGENiHBG066727
InParanoidiQ80Y75
KOiK09519
OMAiAMQKFRI
OrthoDBiEOG091G0DLS
PhylomeDBiQ80Y75
TreeFamiTF105141

Family and domain databases

CDDicd06257 DnaJ, 1 hit
Gene3Di1.10.287.110, 1 hit
InterProiView protein in InterPro
IPR002939 DnaJ_C
IPR001623 DnaJ_domain
IPR018253 DnaJ_domain_CS
IPR008971 HSP40/DnaJ_pept-bd
IPR036869 J_dom_sf
PfamiView protein in Pfam
PF00226 DnaJ, 1 hit
PF01556 DnaJ_C, 1 hit
PRINTSiPR00625 JDOMAIN
SMARTiView protein in SMART
SM00271 DnaJ, 1 hit
SUPFAMiSSF46565 SSF46565, 1 hit
SSF49493 SSF49493, 2 hits
PROSITEiView protein in PROSITE
PS00636 DNAJ_1, 1 hit
PS50076 DNAJ_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q80Y75-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGLDYYAVLQ VTRNSEDAQI KKAYRKLALK NHPLKSSEPG APEIFKQIAE
60 70 80 90 100
AYDVLSDPVK RGIYDKFGEE GLKGGIPLEF GSQTPWTTGY VFHGNPDKVF
110 120 130 140 150
HEFFGGDNPF SEFFDAEGND IDLNFGGLWG RGVQKQDPPI ERDLYLSLED
160 170 180 190 200
LFFGCTKKIK ISRRVLNEDR YSSTIKDKIL TIDVRPGWRQ GTRITFEKEG
210 220 230 240 250
DQGPNIIPAD IIFIVKEKLH PRFRREHDNL FFVYPIPLGK ALTCCTVEVK
260 270 280 290 300
TLDDRLLNIP INDIVHPKYF KIVPGEGMPL PENPSKKGDL FIFFDIQFPT
310
RLTPQKKQML RQALLT
Length:316
Mass (Da):36,155
Last modified:June 1, 2003 - v1
Checksum:i38BBC8271A18C9B5
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti133V → I in AAN32703 (PubMed:14673507).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF419292 mRNA Translation: AAN32703.2
BC048501 mRNA Translation: AAH48501.1
CCDSiCCDS21499.1
RefSeqiNP_705755.2, NM_153527.2
UniGeneiMm.278554

Genome annotation databases

EnsembliENSMUST00000207405; ENSMUSP00000147019; ENSMUSG00000030708
GeneIDi69387
KEGGimmu:69387
UCSCiuc009inc.1 mouse

Similar proteinsi

Entry informationi

Entry nameiDJB13_MOUSE
AccessioniPrimary (citable) accession number: Q80Y75
Secondary accession number(s): Q8CJA2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 10, 2003
Last sequence update: June 1, 2003
Last modified: April 25, 2018
This is version 111 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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Main funding by: National Institutes of Health