Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

DnaJ homolog subfamily B member 13

Gene

Dnajb13

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

May play a role in the formation of the central complex of ciliary and flagellar axonemes.By similarity

GO - Biological processi

Keywordsi

Molecular functionChaperone
Biological processCilium biogenesis/degradation

Names & Taxonomyi

Protein namesi
Recommended name:
DnaJ homolog subfamily B member 13
Alternative name(s):
Testis and spermatogenesis cell-related protein 6
Testis spermatocyte apoptosis-related gene 6 protein
Testis spermatogenesis apoptosis-related gene 3 protein
Testis spermatogenesis apoptosis-related gene 6 protein
Gene namesi
Name:Dnajb13
Synonyms:Tsarg, Tsarg3, Tsarg6
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 7

Organism-specific databases

MGIiMGI:1916637. Dnajb13.

Subcellular locationi

  • Cell projectionciliumflagellum By similarity

  • Note: Localizes both to epithelial motile cilium and the sperm flagellum.By similarity

GO - Cellular componenti

  • axoneme Source: MGI
  • cytoplasm Source: MGI
  • motile cilium Source: UniProtKB
  • sperm flagellum Source: UniProtKB

Keywords - Cellular componenti

Cell projection, Cilium, Flagellum

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000710401 – 316DnaJ homolog subfamily B member 13Add BLAST316

Proteomic databases

MaxQBiQ80Y75.
PaxDbiQ80Y75.
PRIDEiQ80Y75.

2D gel databases

REPRODUCTION-2DPAGEQ80Y75.

PTM databases

PhosphoSitePlusiQ80Y75.

Expressioni

Tissue specificityi

Specifically expressed in testis.1 Publication

Gene expression databases

BgeeiENSMUSG00000030708.
CleanExiMM_DNAJB13.
ExpressionAtlasiQ80Y75. baseline and differential.
GenevisibleiQ80Y75. MM.

Interactioni

Subunit structurei

Homodimer.By similarity

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000059074.

Structurei

3D structure databases

ProteinModelPortaliQ80Y75.
SMRiQ80Y75.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini4 – 68JPROSITE-ProRule annotationAdd BLAST65

Phylogenomic databases

eggNOGiKOG0714. Eukaryota.
COG0484. LUCA.
GeneTreeiENSGT00760000118947.
HOGENOMiHOG000226718.
HOVERGENiHBG066727.
InParanoidiQ80Y75.
KOiK09519.
OMAiDNPFGEF.
OrthoDBiEOG090B08ZT.
PhylomeDBiQ80Y75.
TreeFamiTF105141.

Family and domain databases

CDDicd06257. DnaJ. 1 hit.
Gene3Di1.10.287.110. 1 hit.
InterProiView protein in InterPro
IPR002939. DnaJ_C.
IPR001623. DnaJ_domain.
IPR018253. DnaJ_domain_CS.
IPR008971. HSP40/DnaJ_pept-bd.
PfamiView protein in Pfam
PF00226. DnaJ. 1 hit.
PF01556. DnaJ_C. 1 hit.
PRINTSiPR00625. JDOMAIN.
SMARTiView protein in SMART
SM00271. DnaJ. 1 hit.
SUPFAMiSSF46565. SSF46565. 1 hit.
SSF49493. SSF49493. 2 hits.
PROSITEiView protein in PROSITE
PS00636. DNAJ_1. 1 hit.
PS50076. DNAJ_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q80Y75-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGLDYYAVLQ VTRNSEDAQI KKAYRKLALK NHPLKSSEPG APEIFKQIAE
60 70 80 90 100
AYDVLSDPVK RGIYDKFGEE GLKGGIPLEF GSQTPWTTGY VFHGNPDKVF
110 120 130 140 150
HEFFGGDNPF SEFFDAEGND IDLNFGGLWG RGVQKQDPPI ERDLYLSLED
160 170 180 190 200
LFFGCTKKIK ISRRVLNEDR YSSTIKDKIL TIDVRPGWRQ GTRITFEKEG
210 220 230 240 250
DQGPNIIPAD IIFIVKEKLH PRFRREHDNL FFVYPIPLGK ALTCCTVEVK
260 270 280 290 300
TLDDRLLNIP INDIVHPKYF KIVPGEGMPL PENPSKKGDL FIFFDIQFPT
310
RLTPQKKQML RQALLT
Length:316
Mass (Da):36,155
Last modified:June 1, 2003 - v1
Checksum:i38BBC8271A18C9B5
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti133V → I in AAN32703 (PubMed:14673507).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF419292 mRNA. Translation: AAN32703.2.
BC048501 mRNA. Translation: AAH48501.1.
CCDSiCCDS21499.1.
RefSeqiNP_705755.2. NM_153527.2.
UniGeneiMm.278554.

Genome annotation databases

EnsembliENSMUST00000207405; ENSMUSP00000147019; ENSMUSG00000030708.
GeneIDi69387.
KEGGimmu:69387.
UCSCiuc009inc.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF419292 mRNA. Translation: AAN32703.2.
BC048501 mRNA. Translation: AAH48501.1.
CCDSiCCDS21499.1.
RefSeqiNP_705755.2. NM_153527.2.
UniGeneiMm.278554.

3D structure databases

ProteinModelPortaliQ80Y75.
SMRiQ80Y75.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000059074.

PTM databases

PhosphoSitePlusiQ80Y75.

2D gel databases

REPRODUCTION-2DPAGEQ80Y75.

Proteomic databases

MaxQBiQ80Y75.
PaxDbiQ80Y75.
PRIDEiQ80Y75.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000207405; ENSMUSP00000147019; ENSMUSG00000030708.
GeneIDi69387.
KEGGimmu:69387.
UCSCiuc009inc.1. mouse.

Organism-specific databases

CTDi374407.
MGIiMGI:1916637. Dnajb13.

Phylogenomic databases

eggNOGiKOG0714. Eukaryota.
COG0484. LUCA.
GeneTreeiENSGT00760000118947.
HOGENOMiHOG000226718.
HOVERGENiHBG066727.
InParanoidiQ80Y75.
KOiK09519.
OMAiDNPFGEF.
OrthoDBiEOG090B08ZT.
PhylomeDBiQ80Y75.
TreeFamiTF105141.

Miscellaneous databases

PROiQ80Y75.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000030708.
CleanExiMM_DNAJB13.
ExpressionAtlasiQ80Y75. baseline and differential.
GenevisibleiQ80Y75. MM.

Family and domain databases

CDDicd06257. DnaJ. 1 hit.
Gene3Di1.10.287.110. 1 hit.
InterProiView protein in InterPro
IPR002939. DnaJ_C.
IPR001623. DnaJ_domain.
IPR018253. DnaJ_domain_CS.
IPR008971. HSP40/DnaJ_pept-bd.
PfamiView protein in Pfam
PF00226. DnaJ. 1 hit.
PF01556. DnaJ_C. 1 hit.
PRINTSiPR00625. JDOMAIN.
SMARTiView protein in SMART
SM00271. DnaJ. 1 hit.
SUPFAMiSSF46565. SSF46565. 1 hit.
SSF49493. SSF49493. 2 hits.
PROSITEiView protein in PROSITE
PS00636. DNAJ_1. 1 hit.
PS50076. DNAJ_2. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiDJB13_MOUSE
AccessioniPrimary (citable) accession number: Q80Y75
Secondary accession number(s): Q8CJA2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 10, 2003
Last sequence update: June 1, 2003
Last modified: February 15, 2017
This is version 104 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.