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Protein
Submitted name:

Heat shock protein 90, alpha (Cytosolic), class A member 1

Gene

Hsp90aa1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Stress responseImported

Names & Taxonomyi

Protein namesi
Submitted name:
Heat shock protein 90, alpha (Cytosolic), class A member 1Imported
Submitted name:
MCG14932, isoform CRA_bImported
Gene namesi
Name:Hsp90aa1Imported
Synonyms:HspcaImported
ORF Names:mCG_14932Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:96250. Hsp90aa1.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Expressioni

Gene expression databases

BgeeiENSMUSG00000021270.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000021698.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini40 – 194155HATPase_cInterPro annotationAdd
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili221 – 25535Sequence analysisAdd
BLAST

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG0019. Eukaryota.
KOG0020. Eukaryota.
COG0326. LUCA.
GeneTreeiENSGT00840000129758.
HOVERGENiHBG007374.
KOiK04079.
OMAiVERHEFG.
OrthoDBiEOG091G0270.

Family and domain databases

Gene3Di3.30.565.10. 2 hits.
HAMAPiMF_00505. HSP90. 1 hit.
InterProiIPR003594. HATPase_C.
IPR019805. Heat_shock_protein_90_CS.
IPR001404. Hsp90_fam.
IPR020575. Hsp90_N.
IPR020568. Ribosomal_S5_D2-typ_fold.
[Graphical view]
PANTHERiPTHR11528. PTHR11528. 1 hit.
PfamiPF02518. HATPase_c. 1 hit.
PF00183. HSP90. 1 hit.
[Graphical view]
PIRSFiPIRSF002583. Hsp90. 1 hit.
PRINTSiPR00775. HEATSHOCK90.
SMARTiSM00387. HATPase_c. 1 hit.
[Graphical view]
SUPFAMiSSF54211. SSF54211. 1 hit.
SSF55874. SSF55874. 1 hit.
PROSITEiPS00298. HSP90. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q80Y52-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPEETQTQDQ PMEEEEVETF AFQAEIAQLM SLIINTFYSN KEIFLRELIS
60 70 80 90 100
NSSDALDKIR YESLTDPSKL DSGKELHINL IPSKQDRTLT IVDTGIGMTK
110 120 130 140 150
ADLINNLGTI AKSGTKAFME ALQAGADISM IGQFGVGFYS AYLVAEKVTV
160 170 180 190 200
ITKHNDDEQY AWESSAGGSF TVRTDTGEPM GRGTKVILHL KEDQTEYLEE
210 220 230 240 250
RRIKEIVKKH SQFIGYPITL FVEKERDKEV SDDEAEEKEE KEEEKEKEEK
260 270 280 290 300
ESDDKPEIED VGSDEEEEEK KDGDKKKKKK IKEKYIDQEE LNKTKPIWTR
310 320 330 340 350
NPDDITNEEY GEFYKSLTND WEEHLAVKHF SVEGQLEFRA LLFVPRRAPF
360 370 380 390 400
DLFENRKKKN NIKLYVRRVF IMDNCEELIP EYLNFIRGVV DSEDLPLNIS
410 420 430 440 450
REMLQQSKIL KVIRKNLVKK CLELFTELAE DKENYKKFYE QFSKNIKLGI
460 470 480 490 500
HEDSQNRKKL SELLRYYTSA SGDEMVSLKD YCTRMKENQK HIYFITGETK
510 520 530 540 550
DQVANSAFVE RLRKHGLEVI YMIEPIDEYC VQQLKEFEGK TLVSVTKEGL
560 570 580 590 600
ELPEDEEEKK KQEEKKTKFE NLCKIMKDIL EKKVEKVVVS NRLVTSPCCI
610 620 630 640 650
VTSTYGWTAN MERIMKAQAL RDNSTMGYMA AKKHLEINPD HSIIETLRQK
660 670 680 690 700
AEADKNDKSV KDLVILLYET ALLSSGFSLE DPQTHANRIY RMIKLGLGID
710 720 730
EDDPTVDDTS AAVTEEMPPL EGDDDTSRME EVD
Length:733
Mass (Da):84,788
Last modified:December 21, 2004 - v2
Checksum:iD92B8FD38A463B4E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC049124 mRNA. Translation: AAH49124.2.
BC094024 mRNA. Translation: AAH94024.1.
AK004658 mRNA. Translation: BAB23449.1.
AK147641 mRNA. Translation: BAE28042.1.
AK161276 mRNA. Translation: BAE36287.1.
AK166720 mRNA. Translation: BAE38969.1.
AK166729 mRNA. Translation: BAE38976.1.
AK166847 mRNA. Translation: BAE39066.1.
AK167114 mRNA. Translation: BAE39262.1.
AK167171 mRNA. Translation: BAE39308.1.
AK167188 mRNA. Translation: BAE39319.1.
AK168605 mRNA. Translation: BAE40472.1.
AK168620 mRNA. Translation: BAE40484.1.
CH466549 Genomic DNA. Translation: EDL18666.1.
RefSeqiNP_034610.1. NM_010480.5.
UniGeneiMm.1843.
Mm.315997.
Mm.341186.
Mm.440626.
Mm.486334.

Genome annotation databases

GeneIDi15519.
KEGGimmu:15519.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC049124 mRNA. Translation: AAH49124.2.
BC094024 mRNA. Translation: AAH94024.1.
AK004658 mRNA. Translation: BAB23449.1.
AK147641 mRNA. Translation: BAE28042.1.
AK161276 mRNA. Translation: BAE36287.1.
AK166720 mRNA. Translation: BAE38969.1.
AK166729 mRNA. Translation: BAE38976.1.
AK166847 mRNA. Translation: BAE39066.1.
AK167114 mRNA. Translation: BAE39262.1.
AK167171 mRNA. Translation: BAE39308.1.
AK167188 mRNA. Translation: BAE39319.1.
AK168605 mRNA. Translation: BAE40472.1.
AK168620 mRNA. Translation: BAE40484.1.
CH466549 Genomic DNA. Translation: EDL18666.1.
RefSeqiNP_034610.1. NM_010480.5.
UniGeneiMm.1843.
Mm.315997.
Mm.341186.
Mm.440626.
Mm.486334.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000021698.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi15519.
KEGGimmu:15519.

Organism-specific databases

CTDi3320.
MGIiMGI:96250. Hsp90aa1.

Phylogenomic databases

eggNOGiKOG0019. Eukaryota.
KOG0020. Eukaryota.
COG0326. LUCA.
GeneTreeiENSGT00840000129758.
HOVERGENiHBG007374.
KOiK04079.
OMAiVERHEFG.
OrthoDBiEOG091G0270.

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000021270.

Family and domain databases

Gene3Di3.30.565.10. 2 hits.
HAMAPiMF_00505. HSP90. 1 hit.
InterProiIPR003594. HATPase_C.
IPR019805. Heat_shock_protein_90_CS.
IPR001404. Hsp90_fam.
IPR020575. Hsp90_N.
IPR020568. Ribosomal_S5_D2-typ_fold.
[Graphical view]
PANTHERiPTHR11528. PTHR11528. 1 hit.
PfamiPF02518. HATPase_c. 1 hit.
PF00183. HSP90. 1 hit.
[Graphical view]
PIRSFiPIRSF002583. Hsp90. 1 hit.
PRINTSiPR00775. HEATSHOCK90.
SMARTiSM00387. HATPase_c. 1 hit.
[Graphical view]
SUPFAMiSSF54211. SSF54211. 1 hit.
SSF55874. SSF55874. 1 hit.
PROSITEiPS00298. HSP90. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ80Y52_MOUSE
AccessioniPrimary (citable) accession number: Q80Y52
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: December 21, 2004
Last modified: September 7, 2016
This is version 137 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Proteomics identificationCombined sources

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.