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Q80XL8

- Q80XL8_MOUSE

UniProt

Q80XL8 - Q80XL8_MOUSE

Protein
Submitted name:

Cngb1 protein

Gene

Cngb1

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 77 (01 Oct 2014)
      Sequence version 1 (01 Jun 2003)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. cGMP binding Source: RefGenome
    2. cyclic nucleotide-gated ion channel activity Source: MGI
    3. intracellular cAMP activated cation channel activity Source: RefGenome
    4. intracellular cGMP activated cation channel activity Source: RefGenome
    5. voltage-gated potassium channel activity Source: RefGenome

    GO - Biological processi

    1. photoreceptor cell maintenance Source: MGI
    2. phototransduction Source: MGI
    3. phototransduction, visible light Source: RefGenome
    4. potassium ion transmembrane transport Source: RefGenome
    5. protein localization to organelle Source: MGI
    6. regulation of membrane potential Source: RefGenome
    7. sensory perception of smell Source: MGI

    Enzyme and pathway databases

    ReactomeiREACT_188252. Activation of the phototransduction cascade.
    REACT_188266. Inactivation, recovery and regulation of the phototransduction cascade.

    Protein family/group databases

    TCDBi1.A.1.5.4. the voltage-gated ion channel (vic) superfamily.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Cngb1 proteinImported
    Gene namesi
    Name:Cngb1Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

    Organism-specific databases

    MGIiMGI:2664102. Cngb1.

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of plasma membrane Source: RefGenome
    2. membrane Source: MGI

    PTM / Processingi

    PTM databases

    PhosphoSiteiQ80XL8.

    Expressioni

    Gene expression databases

    BgeeiQ80XL8.
    GenevestigatoriQ80XL8.

    Structurei

    3D structure databases

    ProteinModelPortaliQ80XL8.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    HOGENOMiHOG000231425.
    HOVERGENiHBG051038.
    InParanoidiQ80XL8.
    KOiK04952.

    Family and domain databases

    Gene3Di2.60.120.10. 1 hit.
    InterProiIPR018490. cNMP-bd-like.
    IPR018488. cNMP-bd_CS.
    IPR000595. cNMP-bd_dom.
    IPR014710. RmlC-like_jellyroll.
    [Graphical view]
    PfamiPF00027. cNMP_binding. 1 hit.
    [Graphical view]
    SMARTiSM00100. cNMP. 1 hit.
    [Graphical view]
    SUPFAMiSSF51206. SSF51206. 1 hit.
    PROSITEiPS00888. CNMP_BINDING_1. 1 hit.
    PS00889. CNMP_BINDING_2. 1 hit.
    PS50042. CNMP_BINDING_3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    Q80XL8-1 [UniParc]FASTAAdd to Basket

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    EEEPIVLLDS CLVVQADVDE CQLERTPSEL ASIQELPEEK EEKEEEKEEE    50
    KEEEEEKKEE EVEKKEEGEA TNSTVPATKE HPELQVEDTD ADSGPLIPEE 100
    TLPPPERPPP SPVKSDTLTV PGAAAAGHRK KLPSQDDEAE ELKALSPAES 150
    PVVAWSDPTT PQEADGQDRA ASTASQNSAI INDRLQELVK MFKERTEKVK 200
    EKLIDPDVTS DEESPKPSPA KKAPEPDPAQ KPAEAEVAEE EHYCDMLCCK 250
    FKRRPLKMYR FPQSIDPLTN LMYILWLFFV VLAWNWNCWL IPVRWAFPYQ 300
    RADNIHFWLL MDYLCDFIYL LDITVFQMRL QFVKGGDIIT DKKEMRNNYL 350
    KSRRFKMDLL CLLPLDFLYL KLGINPLLRL PRCLKYMAFF EFNNRLEAIL 400
    SKAYVYRVIR TTAYLLYSLH LNSCLYYWAS AFQGIGSTHW VYDGVGNSYI 450
    RCYYWAVKTL ITIGGLPDPQ TLFEIVFQLL NYFTGVFAFS VMIGQMRDVV 500
    GAATAGQTYY RSCMDSTVKY MNFYKIPRSV QNRVKTWYEY TWHSQGMLDE 550
    SELMVQLPDK MRLDLAIDVN YSIVSKVALF QGCDRQMIFD MLKRLRSVVY 600
    LPNDYVCKKG EIGREMYIIQ AGQVQVLGGP DGKAVLVTLK AGSVFGEISL 650
    LAVGGGNRRT ANVVAHGFTN LFILDKKDLN EILVHYPESQ KLLRKKARRM 700
    LRNNNKPKEE KSVLILPPRA GTPKLFNAAL AAAGKMGPRG AKGGKLAHLR 750
    ARLKELAALE AAARQQQLLE QAKSSQEAGG EEGSGATDQP APQEPPEPKD 800
    PPKPPGPPEP SAQSSPPPAS AKPEESTGEA AGPPEPSVRI RVSPGPDPGE 850
    QTLSVEVLEE KKEGAE 866
    Length:866
    Mass (Da):97,427
    Last modified:June 1, 2003 - v1
    Checksum:iCACC4AD8EB6DEE2A
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC045114 mRNA. Translation: AAH45114.1.
    RefSeqiNP_001182342.1. NM_001195413.1.
    UniGeneiMm.484049.
    Mm.491649.

    Genome annotation databases

    GeneIDi333329.
    KEGGimmu:333329.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC045114 mRNA. Translation: AAH45114.1 .
    RefSeqi NP_001182342.1. NM_001195413.1.
    UniGenei Mm.484049.
    Mm.491649.

    3D structure databases

    ProteinModelPortali Q80XL8.
    ModBasei Search...
    MobiDBi Search...

    Protein family/group databases

    TCDBi 1.A.1.5.4. the voltage-gated ion channel (vic) superfamily.

    PTM databases

    PhosphoSitei Q80XL8.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 333329.
    KEGGi mmu:333329.

    Organism-specific databases

    CTDi 1258.
    MGIi MGI:2664102. Cngb1.

    Phylogenomic databases

    HOGENOMi HOG000231425.
    HOVERGENi HBG051038.
    InParanoidi Q80XL8.
    KOi K04952.

    Enzyme and pathway databases

    Reactomei REACT_188252. Activation of the phototransduction cascade.
    REACT_188266. Inactivation, recovery and regulation of the phototransduction cascade.

    Miscellaneous databases

    NextBioi 399967.
    SOURCEi Search...

    Gene expression databases

    Bgeei Q80XL8.
    Genevestigatori Q80XL8.

    Family and domain databases

    Gene3Di 2.60.120.10. 1 hit.
    InterProi IPR018490. cNMP-bd-like.
    IPR018488. cNMP-bd_CS.
    IPR000595. cNMP-bd_dom.
    IPR014710. RmlC-like_jellyroll.
    [Graphical view ]
    Pfami PF00027. cNMP_binding. 1 hit.
    [Graphical view ]
    SMARTi SM00100. cNMP. 1 hit.
    [Graphical view ]
    SUPFAMi SSF51206. SSF51206. 1 hit.
    PROSITEi PS00888. CNMP_BINDING_1. 1 hit.
    PS00889. CNMP_BINDING_2. 1 hit.
    PS50042. CNMP_BINDING_3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
      , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: EyeImported.

    Entry informationi

    Entry nameiQ80XL8_MOUSE
    AccessioniPrimary (citable) accession number: Q80XL8
    Entry historyi
    Integrated into UniProtKB/TrEMBL: June 1, 2003
    Last sequence update: June 1, 2003
    Last modified: October 1, 2014
    This is version 77 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)