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Protein
Submitted name:

Cngb1 protein

Gene

Cngb1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. cGMP binding Source: GO_Central
  2. cyclic nucleotide-gated ion channel activity Source: MGI
  3. intracellular cAMP activated cation channel activity Source: GO_Central
  4. intracellular cGMP activated cation channel activity Source: GO_Central
  5. voltage-gated potassium channel activity Source: GO_Central

GO - Biological processi

  1. photoreceptor cell maintenance Source: MGI
  2. phototransduction Source: MGI
  3. phototransduction, visible light Source: GO_Central
  4. potassium ion transmembrane transport Source: GO_Central
  5. protein localization to organelle Source: MGI
  6. regulation of membrane potential Source: GO_Central
  7. sensory perception of smell Source: MGI
Complete GO annotation...

Protein family/group databases

TCDBi1.A.1.5.4. the voltage-gated ion channel (vic) superfamily.

Names & Taxonomyi

Protein namesi
Submitted name:
Cngb1 proteinImported
Gene namesi
Name:Cngb1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:2664102. Cngb1.

Subcellular locationi

GO - Cellular componenti

  1. integral component of plasma membrane Source: GO_Central
  2. membrane Source: MGI
  3. photoreceptor outer segment Source: MGI
Complete GO annotation...

PTM / Processingi

PTM databases

PhosphoSiteiQ80XL8.

Expressioni

Gene expression databases

BgeeiQ80XL8.
ExpressionAtlasiQ80XL8. baseline and differential.
GenevestigatoriQ80XL8.

Structurei

3D structure databases

ProteinModelPortaliQ80XL8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000231425.
HOVERGENiHBG051038.
KOiK04952.

Family and domain databases

Gene3Di2.60.120.10. 1 hit.
InterProiIPR018490. cNMP-bd-like.
IPR018488. cNMP-bd_CS.
IPR000595. cNMP-bd_dom.
IPR014710. RmlC-like_jellyroll.
[Graphical view]
PfamiPF00027. cNMP_binding. 1 hit.
[Graphical view]
SMARTiSM00100. cNMP. 1 hit.
[Graphical view]
SUPFAMiSSF51206. SSF51206. 1 hit.
PROSITEiPS00888. CNMP_BINDING_1. 1 hit.
PS00889. CNMP_BINDING_2. 1 hit.
PS50042. CNMP_BINDING_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q80XL8-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
EEEPIVLLDS CLVVQADVDE CQLERTPSEL ASIQELPEEK EEKEEEKEEE
60 70 80 90 100
KEEEEEKKEE EVEKKEEGEA TNSTVPATKE HPELQVEDTD ADSGPLIPEE
110 120 130 140 150
TLPPPERPPP SPVKSDTLTV PGAAAAGHRK KLPSQDDEAE ELKALSPAES
160 170 180 190 200
PVVAWSDPTT PQEADGQDRA ASTASQNSAI INDRLQELVK MFKERTEKVK
210 220 230 240 250
EKLIDPDVTS DEESPKPSPA KKAPEPDPAQ KPAEAEVAEE EHYCDMLCCK
260 270 280 290 300
FKRRPLKMYR FPQSIDPLTN LMYILWLFFV VLAWNWNCWL IPVRWAFPYQ
310 320 330 340 350
RADNIHFWLL MDYLCDFIYL LDITVFQMRL QFVKGGDIIT DKKEMRNNYL
360 370 380 390 400
KSRRFKMDLL CLLPLDFLYL KLGINPLLRL PRCLKYMAFF EFNNRLEAIL
410 420 430 440 450
SKAYVYRVIR TTAYLLYSLH LNSCLYYWAS AFQGIGSTHW VYDGVGNSYI
460 470 480 490 500
RCYYWAVKTL ITIGGLPDPQ TLFEIVFQLL NYFTGVFAFS VMIGQMRDVV
510 520 530 540 550
GAATAGQTYY RSCMDSTVKY MNFYKIPRSV QNRVKTWYEY TWHSQGMLDE
560 570 580 590 600
SELMVQLPDK MRLDLAIDVN YSIVSKVALF QGCDRQMIFD MLKRLRSVVY
610 620 630 640 650
LPNDYVCKKG EIGREMYIIQ AGQVQVLGGP DGKAVLVTLK AGSVFGEISL
660 670 680 690 700
LAVGGGNRRT ANVVAHGFTN LFILDKKDLN EILVHYPESQ KLLRKKARRM
710 720 730 740 750
LRNNNKPKEE KSVLILPPRA GTPKLFNAAL AAAGKMGPRG AKGGKLAHLR
760 770 780 790 800
ARLKELAALE AAARQQQLLE QAKSSQEAGG EEGSGATDQP APQEPPEPKD
810 820 830 840 850
PPKPPGPPEP SAQSSPPPAS AKPEESTGEA AGPPEPSVRI RVSPGPDPGE
860
QTLSVEVLEE KKEGAE
Length:866
Mass (Da):97,427
Last modified:June 1, 2003 - v1
Checksum:iCACC4AD8EB6DEE2A
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC045114 mRNA. Translation: AAH45114.1.
RefSeqiNP_001182342.1. NM_001195413.1.
UniGeneiMm.484049.
Mm.491649.

Genome annotation databases

GeneIDi333329.
KEGGimmu:333329.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC045114 mRNA. Translation: AAH45114.1.
RefSeqiNP_001182342.1. NM_001195413.1.
UniGeneiMm.484049.
Mm.491649.

3D structure databases

ProteinModelPortaliQ80XL8.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

TCDBi1.A.1.5.4. the voltage-gated ion channel (vic) superfamily.

PTM databases

PhosphoSiteiQ80XL8.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi333329.
KEGGimmu:333329.

Organism-specific databases

CTDi1258.
MGIiMGI:2664102. Cngb1.

Phylogenomic databases

HOGENOMiHOG000231425.
HOVERGENiHBG051038.
KOiK04952.

Miscellaneous databases

ChiTaRSiCngb1. mouse.
NextBioi399967.
SOURCEiSearch...

Gene expression databases

BgeeiQ80XL8.
ExpressionAtlasiQ80XL8. baseline and differential.
GenevestigatoriQ80XL8.

Family and domain databases

Gene3Di2.60.120.10. 1 hit.
InterProiIPR018490. cNMP-bd-like.
IPR018488. cNMP-bd_CS.
IPR000595. cNMP-bd_dom.
IPR014710. RmlC-like_jellyroll.
[Graphical view]
PfamiPF00027. cNMP_binding. 1 hit.
[Graphical view]
SMARTiSM00100. cNMP. 1 hit.
[Graphical view]
SUPFAMiSSF51206. SSF51206. 1 hit.
PROSITEiPS00888. CNMP_BINDING_1. 1 hit.
PS00889. CNMP_BINDING_2. 1 hit.
PS50042. CNMP_BINDING_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: EyeImported.

Entry informationi

Entry nameiQ80XL8_MOUSE
AccessioniPrimary (citable) accession number: Q80XL8
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: June 1, 2003
Last modified: February 4, 2015
This is version 81 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.