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Protein
Submitted name:

DEAH (Asp-Glu-Ala-His) box polypeptide 38

Gene

Dhx38

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolaseSAAS annotation
LigandATP-bindingSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-MMU-109688. Cleavage of Growing Transcript in the Termination Region.
R-MMU-159236. Transport of Mature mRNA derived from an Intron-Containing Transcript.
R-MMU-72163. mRNA Splicing - Major Pathway.
R-MMU-72187. mRNA 3'-end processing.

Names & Taxonomyi

Protein namesi
Submitted name:
DEAH (Asp-Glu-Ala-His) box polypeptide 38Imported
Gene namesi
Name:Dhx38Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 8

Organism-specific databases

MGIiMGI:1927617. Dhx38.

Subcellular locationi

GO - Cellular componenti

Expressioni

Gene expression databases

BgeeiENSMUSG00000037993.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000047865.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini543 – 706Helicase ATP-bindingInterPro annotationAdd BLAST164
Domaini728 – 903Helicase C-terminalInterPro annotationAdd BLAST176

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili1156 – 1193Sequence analysisAdd BLAST38

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG0924. Eukaryota.
COG1643. LUCA.
GeneTreeiENSGT00880000137867.
HOGENOMiHOG000175261.
HOVERGENiHBG039428.
KOiK12815.
OMAiPSRSTWE.
OrthoDBiEOG091G030Q.
TreeFamiTF105793.

Family and domain databases

InterProiView protein in InterPro
IPR011545. DEAD/DEAH_box_helicase_dom.
IPR002464. DNA/RNA_helicase_DEAH_CS.
IPR011709. DUF1605.
IPR007502. Helicase-assoc_dom.
IPR014001. Helicase_ATP-bd.
IPR001650. Helicase_C.
IPR027417. P-loop_NTPase.
PfamiView protein in Pfam
PF00270. DEAD. 1 hit.
PF04408. HA2. 1 hit.
PF00271. Helicase_C. 1 hit.
PF07717. OB_NTP_bind. 1 hit.
SMARTiView protein in SMART
SM00487. DEXDc. 1 hit.
SM00847. HA2. 1 hit.
SM00490. HELICc. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiView protein in PROSITE
PS00690. DEAH_ATP_HELICASE. 1 hit.
PS51192. HELICASE_ATP_BIND_1. 1 hit.
PS51194. HELICASE_CTER. 1 hit.

Sequencei

Sequence statusi: Complete.

Q80X98-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEDPGEDTSI HRLEGTSLDS QVGGLICKTK SAANEQHVFK APAPRPSLLG
60 70 80 90 100
LDLLASLKRR EREEKDDGED KKKSRVSSYK DWEESKDDQK DAEEESEDQA
110 120 130 140 150
GRSSRRDRHY RSARVETPSH PGGVSEEFWE RSRQRERDRR EHGVYASSKE
160 170 180 190 200
EKDRKKERSR DRDYDRKRDR ADERDRSRHS SRSDRDGGSE RSSRRNEPES
210 220 230 240 250
PRHRPKDAAT PSRSAWEEDD SGYGSSRRSQ WETPSPTPSY RDSERGHRPS
260 270 280 290 300
TRDRDRSIRS KSSDDTPLPT PSYKYNEWAD DRRHLGSTPR LSRGRGRRED
310 320 330 340 350
GEEGIAFDTE EERQQWEDDQ RQADRDWYMM DEGYDEFHNP LAYSSEDYVR
360 370 380 390 400
RREQHLHKQK QKRISAQRRQ INEDNERWET NRMLTSGVVH RLEVDEDFEE
410 420 430 440 450
DNAAKVHLMV HNLVPPFLDG RIVFTKQPEP VIPVKDATSD LAIIARKGSQ
460 470 480 490 500
TVRKHREQKE RRKAQHKHWE LAGTKLGDIM GVKKEEEPDK AMTEDGKVDY
510 520 530 540 550
RTEQKFADHM KEKSEASSEF AKKKSILEQR QYLPIFAVQQ ELLTIIRDNS
560 570 580 590 600
IVIVVGETGS GKTTQLTQYL HEDGYTDYGM IGCTQPRRVA AMSVAKRVSE
610 620 630 640 650
EMGGNLGEEV GYAIRFEDCT SENTLIKYMT DGILLRESLR EADLDHYSAV
660 670 680 690 700
IMDEAHERSL NTDVLFGLLR EVVARRSDLK LIVTSATMDA EKFAAFFGNV
710 720 730 740 750
PIFHIPGRTF PVDILFSKTP QEDYVEAAVK QSLQVHLSGA PGDILIFMPG
760 770 780 790 800
QEDIEVTSDQ IVEHLEELEN APALAVLPIY SQLPSDLQAK IFQKAPDGVR
810 820 830 840 850
KCIVATNIAE TSLTVDGIMF VIDSGYCKLK VFNPRIGMDA LQIYPISQAN
860 870 880 890 900
ANQRSGRAGR TGPGQCFRLY TQSAYKNELL TTTVPEIQRT NLANVVLLLK
910 920 930 940 950
SLGVQDLLQF HFMDPPPEDN MLNSMYQLWI LGALDNTGGL TSTGRLMVEF
960 970 980 990 1000
PLDPALSKML IVSCDMGCSS EILLIVSMLS VPAIFYRPKG REEESDQIRE
1010 1020 1030 1040 1050
KFAVPESDHL TYLNVYLQWK NNNYSTIWCN DHFIHAKAMR KVREVRAQLK
1060 1070 1080 1090 1100
DIMVQQRMSL ASCGTDWDIV RKCICAAYFH QAAKLKGIGE YVNIRTGMPC
1110 1120 1130 1140 1150
HLHPTSSLFG MGYTPDYIVY HELVMTTKEY MQCVTAVDGE WLAELGPMFY
1160 1170 1180 1190 1200
SVKQAGKSRQ ENRRRAKEEA SAMEEEMALA EEQLRARRQE QEKRSPLGSV
1210 1220
RSTKIYTPGR KEQGEPMTPR RTPARFGL
Length:1,228
Mass (Da):140,623
Last modified:June 1, 2003 - v1
Checksum:iCDA4D07FCC95FA49
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC125162 Genomic DNA. No translation available.
BC046557 mRNA. Translation: AAH46557.1.
AK153917 mRNA. Translation: BAE32255.1.
RefSeqiNP_848467.1. NM_178380.1.
UniGeneiMm.23705.

Genome annotation databases

EnsembliENSMUST00000042601; ENSMUSP00000047865; ENSMUSG00000037993.
GeneIDi64340.
KEGGimmu:64340.
UCSCiuc009nij.1. mouse.

Similar proteinsi

Entry informationi

Entry nameiQ80X98_MOUSE
AccessioniPrimary (citable) accession number: Q80X98
Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: June 1, 2003
Last modified: August 30, 2017
This is version 129 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported