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Protein
Submitted name:

CD44 antigen

Gene

Cd44

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-MMU-1474228. Degradation of the extracellular matrix.
R-MMU-202733. Cell surface interactions at the vascular wall.
R-MMU-216083. Integrin cell surface interactions.
R-MMU-2160916. Hyaluronan uptake and degradation.
R-MMU-6798695. Neutrophil degranulation.

Names & Taxonomyi

Protein namesi
Submitted name:
CD44 antigenImported
Submitted name:
Cd44 proteinImported
Gene namesi
Name:Cd44Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 2

Organism-specific databases

MGIiMGI:88338. Cd44.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei488 – 509HelicalSequence analysisAdd BLAST22

GO - Cellular componenti

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 20Sequence analysisAdd BLAST20
ChainiPRO_501084673321 – 580Sequence analysisAdd BLAST560

Expressioni

Gene expression databases

BgeeiENSMUSG00000005087.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini36 – 125LinkInterPro annotationAdd BLAST90

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IZCP. Eukaryota.
ENOG4111S6T. LUCA.
GeneTreeiENSGT00530000063822.
HOGENOMiHOG000231746.
HOVERGENiHBG003850.

Family and domain databases

Gene3Di3.10.100.10. 1 hit.
InterProiView protein in InterPro
IPR016186. C-type_lectin-like/link.
IPR001231. CD44_antigen.
IPR016187. CTDL_fold.
IPR000538. Link_dom.
PANTHERiPTHR10225:SF8. PTHR10225:SF8. 1 hit.
PfamiView protein in Pfam
PF00193. Xlink. 1 hit.
PRINTSiPR00658. CD44.
PR01265. LINKMODULE.
SMARTiView protein in SMART
SM00445. LINK. 1 hit.
SUPFAMiSSF56436. SSF56436. 1 hit.
PROSITEiView protein in PROSITE
PS01241. LINK_1. 1 hit.
PS50963. LINK_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q80X37-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDKFWWHTAW GLCLLQLSLA HPHQQIDLNV TCRYAGVFHV EKNGRYSISR
60 70 80 90 100
TEAADLCQAF NSTLPTMDQM KLALSKGFET CRYGFIEGNV VIPRIHPNAI
110 120 130 140 150
CAANHTGVYI LVTSNTSHYD TYCFNASAPP EEDCTSVTDL PNSFDGPVTI
160 170 180 190 200
TIVNRDGTRY SKKGEYRTHQ EDIDASNIID DDVSSGSTIE KSTPESYILH
210 220 230 240 250
TYLPTEQPTG DQDDSFFIRS TLATTPNSTA EAAATQQETW FQNGWQGKNP
260 270 280 290 300
PTPSEDSHVT EGTTASAHNN HPSQRITTQS QEDVSWTDFF DPISHPMGQG
310 320 330 340 350
HQTESKDTDS SHSTTLQPTA APNTHLVEDL NRTGPLSVTT PQSHSQNFST
360 370 380 390 400
LHGEPEEDEN HPTTSILPSS TKSGAKDARR GGSLPTDTTT SVEGYTFQYP
410 420 430 440 450
DTMENGTLFP VTPAKTEVFG ETEVTLATDS NVNVDGSLPG DRDSSKDSRG
460 470 480 490 500
SSRTVTHGSE LAGHSSANQD SGVTTTSGPM RRPQIPEWLI ILASLLALAL
510 520 530 540 550
ILAVCIAVNS RRRCGQKKKL VINGGNGTVE DRKPSELNGE ASKSQEMVHL
560 570 580
VNKEPSETPD QCMTADETRN LQSVDMKIGV
Length:580
Mass (Da):63,264
Last modified:June 1, 2003 - v1
Checksum:iF38A59C9AAB8BA0E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL844155 Genomic DNA. No translation available.
BC051388 mRNA. Translation: AAH51388.1.
CT010324 mRNA. Translation: CAJ18532.1.
RefSeqiNP_001034239.1. NM_001039150.1.
UniGeneiMm.423621.

Genome annotation databases

EnsembliENSMUST00000060516; ENSMUSP00000062330; ENSMUSG00000005087.
GeneIDi12505.
UCSCiuc008lif.2. mouse.

Similar proteinsi

Entry informationi

Entry nameiQ80X37_MOUSE
AccessioniPrimary (citable) accession number: Q80X37
Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: June 1, 2003
Last modified: August 30, 2017
This is version 114 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported