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Q80X28

- Q80X28_MOUSE

UniProt

Q80X28 - Q80X28_MOUSE

Protein
Submitted name:

Nrp1 protein

Gene

Nrp1

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 5 out of 5- Experimental evidence at transcript leveli
  1. Functioni

    GO - Molecular functioni

    1. growth factor binding Source: MGI
    2. protein binding Source: MGI
    3. semaphorin receptor activity Source: MGI
    4. vascular endothelial growth factor-activated receptor activity Source: Ensembl

    GO - Biological processi

    1. angiogenesis Source: MGI
    2. axonal fasciculation Source: MGI
    3. axon guidance Source: MGI
    4. cell migration Source: MGI
    5. cellular response to hepatocyte growth factor stimulus Source: Ensembl
    6. dendrite development Source: MGI
    7. dichotomous subdivision of terminal units involved in salivary gland branching Source: MGI
    8. endothelial cell chemotaxis Source: Ensembl
    9. heart development Source: MGI
    10. hepatocyte growth factor receptor signaling pathway Source: Ensembl
    11. negative regulation of axon extension Source: MGI
    12. negative regulation of axon extension involved in axon guidance Source: MGI
    13. organ morphogenesis Source: InterPro
    14. patterning of blood vessels Source: MGI
    15. platelet-derived growth factor receptor signaling pathway Source: Ensembl
    16. positive regulation of peptidyl-tyrosine phosphorylation Source: Ensembl
    17. regulation of axon extension involved in axon guidance Source: MGI
    18. response to wounding Source: Ensembl
    19. semaphorin-plexin signaling pathway Source: MGI
    20. sympathetic nervous system development Source: MGI
    21. trigeminal nerve morphogenesis Source: MGI
    22. vascular endothelial growth factor receptor signaling pathway Source: MGI

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Nrp1 proteinImported
    Gene namesi
    Name:Nrp1Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

    Organism-specific databases

    MGIiMGI:106206. Nrp1.

    Subcellular locationi

    GO - Cellular componenti

    1. axon Source: MGI
    2. cell surface Source: Ensembl
    3. cytosol Source: Ensembl
    4. growth cone Source: Ensembl
    5. neurofilament Source: MGI
    6. neuronal cell body Source: Ensembl
    7. plasma membrane Source: Ensembl

    Expressioni

    Gene expression databases

    ArrayExpressiQ80X28.
    BgeeiQ80X28.
    GenevestigatoriQ80X28.

    Interactioni

    Protein-protein interaction databases

    STRINGi10090.ENSMUSP00000026917.

    Structurei

    3D structure databases

    ProteinModelPortaliQ80X28.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    InParanoidiQ80X28.

    Family and domain databases

    Gene3Di2.60.120.290. 1 hit.
    InterProiIPR000859. CUB_dom.
    IPR027146. NRP1.
    [Graphical view]
    PANTHERiPTHR10127:SF616. PTHR10127:SF616. 1 hit.
    PfamiPF00431. CUB. 1 hit.
    [Graphical view]
    SMARTiSM00042. CUB. 1 hit.
    [Graphical view]
    SUPFAMiSSF49854. SSF49854. 1 hit.
    PROSITEiPS01180. CUB. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    Q80X28-1 [UniParc]FASTAAdd to Basket

    « Hide

    MERGLPLLCA TLALALALAG AFRSDKCGGT IKIENPGYLT SPGYPHSYHP   50
    SEKCEWLIQA PEPYQRIMIN FNPHFDLEDR DCKYDYVEVI DGENE 95
    Length:95
    Mass (Da):10,748
    Last modified:June 1, 2003 - v1
    Checksum:iF61167BD4910EADB
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei95 – 951Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC051447 mRNA. Translation: AAH51447.1.
    UniGeneiMm.271745.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC051447 mRNA. Translation: AAH51447.1 .
    UniGenei Mm.271745.

    3D structure databases

    ProteinModelPortali Q80X28.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 10090.ENSMUSP00000026917.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Organism-specific databases

    MGIi MGI:106206. Nrp1.

    Phylogenomic databases

    InParanoidi Q80X28.

    Miscellaneous databases

    ChiTaRSi NRP1. mouse.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi Q80X28.
    Bgeei Q80X28.
    Genevestigatori Q80X28.

    Family and domain databases

    Gene3Di 2.60.120.290. 1 hit.
    InterProi IPR000859. CUB_dom.
    IPR027146. NRP1.
    [Graphical view ]
    PANTHERi PTHR10127:SF616. PTHR10127:SF616. 1 hit.
    Pfami PF00431. CUB. 1 hit.
    [Graphical view ]
    SMARTi SM00042. CUB. 1 hit.
    [Graphical view ]
    SUPFAMi SSF49854. SSF49854. 1 hit.
    PROSITEi PS01180. CUB. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
      , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: C3H/HeImported.
      Tissue: OsteoblastImported.

    Entry informationi

    Entry nameiQ80X28_MOUSE
    AccessioniPrimary (citable) accession number: Q80X28
    Entry historyi
    Integrated into UniProtKB/TrEMBL: June 1, 2003
    Last sequence update: June 1, 2003
    Last modified: October 1, 2014
    This is version 65 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)