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Q80X28

- Q80X28_MOUSE

UniProt

Q80X28 - Q80X28_MOUSE

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Protein
Submitted name:

Nrp1 protein

Gene

Nrp1

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 5 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. growth factor binding Source: MGI
  2. semaphorin receptor activity Source: MGI
  3. vascular endothelial growth factor-activated receptor activity Source: Ensembl

GO - Biological processi

  1. angiogenesis Source: MGI
  2. axonal fasciculation Source: MGI
  3. axon guidance Source: MGI
  4. cell migration Source: MGI
  5. cellular response to hepatocyte growth factor stimulus Source: Ensembl
  6. dendrite development Source: MGI
  7. dichotomous subdivision of terminal units involved in salivary gland branching Source: MGI
  8. endothelial cell chemotaxis Source: Ensembl
  9. heart development Source: MGI
  10. hepatocyte growth factor receptor signaling pathway Source: Ensembl
  11. negative regulation of axon extension Source: MGI
  12. negative regulation of axon extension involved in axon guidance Source: MGI
  13. organ morphogenesis Source: InterPro
  14. patterning of blood vessels Source: MGI
  15. platelet-derived growth factor receptor signaling pathway Source: Ensembl
  16. positive regulation of peptidyl-tyrosine phosphorylation Source: Ensembl
  17. regulation of axon extension involved in axon guidance Source: MGI
  18. response to wounding Source: Ensembl
  19. semaphorin-plexin signaling pathway Source: MGI
  20. sympathetic nervous system development Source: MGI
  21. trigeminal nerve morphogenesis Source: MGI
  22. vascular endothelial growth factor receptor signaling pathway Source: MGI
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Nrp1 proteinImported
Gene namesi
Name:Nrp1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:106206. Nrp1.

Subcellular locationi

GO - Cellular componenti

  1. axon Source: MGI
  2. cell surface Source: Ensembl
  3. cytosol Source: Ensembl
  4. extracellular space Source: Ensembl
  5. growth cone Source: Ensembl
  6. neurofilament Source: MGI
  7. neuronal cell body Source: Ensembl
  8. plasma membrane Source: Ensembl
Complete GO annotation...

Expressioni

Gene expression databases

BgeeiQ80X28.
ExpressionAtlasiQ80X28. baseline and differential.
GenevestigatoriQ80X28.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000026917.

Structurei

3D structure databases

ProteinModelPortaliQ80X28.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Family and domain databases

Gene3Di2.60.120.290. 1 hit.
InterProiIPR000859. CUB_dom.
IPR027146. NRP1.
[Graphical view]
PANTHERiPTHR10127:SF616. PTHR10127:SF616. 1 hit.
PfamiPF00431. CUB. 1 hit.
[Graphical view]
SMARTiSM00042. CUB. 1 hit.
[Graphical view]
SUPFAMiSSF49854. SSF49854. 1 hit.
PROSITEiPS01180. CUB. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q80X28-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MERGLPLLCA TLALALALAG AFRSDKCGGT IKIENPGYLT SPGYPHSYHP
60 70 80 90
SEKCEWLIQA PEPYQRIMIN FNPHFDLEDR DCKYDYVEVI DGENE
Length:95
Mass (Da):10,748
Last modified:June 1, 2003 - v1
Checksum:iF61167BD4910EADB
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei95 – 951Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC051447 mRNA. Translation: AAH51447.1.
UniGeneiMm.271745.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC051447 mRNA. Translation: AAH51447.1 .
UniGenei Mm.271745.

3D structure databases

ProteinModelPortali Q80X28.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 10090.ENSMUSP00000026917.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

MGIi MGI:106206. Nrp1.

Miscellaneous databases

ChiTaRSi NRP1. mouse.
SOURCEi Search...

Gene expression databases

Bgeei Q80X28.
ExpressionAtlasi Q80X28. baseline and differential.
Genevestigatori Q80X28.

Family and domain databases

Gene3Di 2.60.120.290. 1 hit.
InterProi IPR000859. CUB_dom.
IPR027146. NRP1.
[Graphical view ]
PANTHERi PTHR10127:SF616. PTHR10127:SF616. 1 hit.
Pfami PF00431. CUB. 1 hit.
[Graphical view ]
SMARTi SM00042. CUB. 1 hit.
[Graphical view ]
SUPFAMi SSF49854. SSF49854. 1 hit.
PROSITEi PS01180. CUB. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: C3H/HeImported.
    Tissue: OsteoblastImported.

Entry informationi

Entry nameiQ80X28_MOUSE
AccessioniPrimary (citable) accession number: Q80X28
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: June 1, 2003
Last modified: October 29, 2014
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)