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Protein
Submitted name:

Nrp1 protein

Gene

Nrp1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • angiogenesis Source: MGI
  • axonal fasciculation Source: MGI
  • axon guidance Source: MGI
  • cell migration Source: MGI
  • cellular response to hepatocyte growth factor stimulus Source: MGI
  • dendrite development Source: MGI
  • dichotomous subdivision of terminal units involved in salivary gland branching Source: MGI
  • endothelial cell chemotaxis Source: MGI
  • heart development Source: MGI
  • hepatocyte growth factor receptor signaling pathway Source: MGI
  • negative regulation of axon extension Source: MGI
  • negative regulation of axon extension involved in axon guidance Source: MGI
  • patterning of blood vessels Source: MGI
  • platelet-derived growth factor receptor signaling pathway Source: MGI
  • positive regulation of peptidyl-tyrosine phosphorylation Source: MGI
  • regulation of axon extension involved in axon guidance Source: MGI
  • semaphorin-plexin signaling pathway Source: MGI
  • sympathetic nervous system development Source: MGI
  • toxin transport Source: MGI
  • trigeminal nerve morphogenesis Source: MGI
  • vascular endothelial growth factor receptor signaling pathway Source: MGI
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Nrp1 proteinImported
Gene namesi
Name:Nrp1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:106206. Nrp1.

Subcellular locationi

GO - Cellular componenti

  • axon Source: MGI
  • cytosol Source: MGI
  • extracellular space Source: MGI
  • focal adhesion Source: MGI
  • neurofilament Source: MGI
  • plasma membrane Source: MGI
Complete GO annotation...

Expressioni

Gene expression databases

BgeeiQ80X28.
ExpressionAtlasiQ80X28. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000026917.

Structurei

3D structure databases

ProteinModelPortaliQ80X28.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Family and domain databases

Gene3Di2.60.120.290. 1 hit.
InterProiIPR000859. CUB_dom.
IPR027146. NRP1.
[Graphical view]
PANTHERiPTHR10127:SF616. PTHR10127:SF616. 1 hit.
PfamiPF00431. CUB. 1 hit.
[Graphical view]
SMARTiSM00042. CUB. 1 hit.
[Graphical view]
SUPFAMiSSF49854. SSF49854. 1 hit.
PROSITEiPS01180. CUB. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q80X28-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MERGLPLLCA TLALALALAG AFRSDKCGGT IKIENPGYLT SPGYPHSYHP
60 70 80 90
SEKCEWLIQA PEPYQRIMIN FNPHFDLEDR DCKYDYVEVI DGENE
Length:95
Mass (Da):10,748
Last modified:June 1, 2003 - v1
Checksum:iF61167BD4910EADB
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei95 – 951Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC051447 mRNA. Translation: AAH51447.1.
UniGeneiMm.271745.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC051447 mRNA. Translation: AAH51447.1.
UniGeneiMm.271745.

3D structure databases

ProteinModelPortaliQ80X28.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000026917.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

MGIiMGI:106206. Nrp1.

Miscellaneous databases

ChiTaRSiNrp1. mouse.
SOURCEiSearch...

Gene expression databases

BgeeiQ80X28.
ExpressionAtlasiQ80X28. baseline and differential.

Family and domain databases

Gene3Di2.60.120.290. 1 hit.
InterProiIPR000859. CUB_dom.
IPR027146. NRP1.
[Graphical view]
PANTHERiPTHR10127:SF616. PTHR10127:SF616. 1 hit.
PfamiPF00431. CUB. 1 hit.
[Graphical view]
SMARTiSM00042. CUB. 1 hit.
[Graphical view]
SUPFAMiSSF49854. SSF49854. 1 hit.
PROSITEiPS01180. CUB. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: C3H/HeImported.
    Tissue: OsteoblastImported.

Entry informationi

Entry nameiQ80X28_MOUSE
AccessioniPrimary (citable) accession number: Q80X28
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: June 1, 2003
Last modified: July 22, 2015
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.