Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q80WM9

- Q80WM9_MOUSE

UniProt

Q80WM9 - Q80WM9_MOUSE

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Submitted name:

Protein Tnfrsf14

Gene

Tnfrsf14

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Biological processi

  1. defense response to Gram-negative bacterium Source: MGI
  2. defense response to Gram-positive bacterium Source: MGI
  3. negative regulation of alpha-beta T cell proliferation Source: MGI
  4. positive regulation of cytokine secretion involved in immune response Source: MGI
  5. positive regulation of peptidyl-tyrosine phosphorylation Source: MGI
  6. positive regulation of T cell migration Source: MGI
Complete GO annotation...

Keywords - Molecular functioni

ReceptorImported

Enzyme and pathway databases

ReactomeiREACT_225477. Costimulation by the CD28 family.

Names & Taxonomyi

Protein namesi
Submitted name:
Protein Tnfrsf14Imported
Submitted name:
Tumor necrosis factor receptor superfamily member 14Imported
Gene namesi
Name:Tnfrsf14Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 4

Organism-specific databases

MGIiMGI:2675303. Tnfrsf14.

Subcellular locationi

GO - Cellular componenti

  1. external side of plasma membrane Source: MGI
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 3838 PotentialImportedAdd
BLAST
Chaini39 – 275237 PotentialImportedPRO_5000090558Add
BLAST

Expressioni

Gene expression databases

GenevestigatoriQ80WM9.

Interactioni

Protein-protein interaction databases

IntActiQ80WM9. 2 interactions.

Structurei

3D structure databases

SMRiQ80WM9. Positions 40-205.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

SignalImported

Phylogenomic databases

GeneTreeiENSGT00760000119204.
HOVERGENiHBG072084.
KOiK05152.
OMAiKEACGEL.
PhylomeDBiQ80WM9.
TreeFamiTF331157.

Family and domain databases

InterProiIPR001368. TNFR/NGFR_Cys_rich_reg.
IPR022332. TNFR_14.
[Graphical view]
PfamiPF00020. TNFR_c6. 1 hit.
[Graphical view]
PRINTSiPR01965. TNFACTORR14.
SMARTiSM00208. TNFR. 4 hits.
[Graphical view]
PROSITEiPS00652. TNFR_NGFR_1. 1 hit.
PS50050. TNFR_NGFR_2. 3 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q80WM9-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MEPLPGWGSA PWSQAPTDNT FRLVPCVFLL NLLQRISAQP SCRQEEFLVG
60 70 80 90 100
DECCPMCNPG YHVKQVCSEH TGTVCAPCPP QTYTAHANGL SKCLPCGVCD
110 120 130 140 150
PDMGLLTWQE CSSWKDTVCR CIPGYFCENQ DGSHCSTCLQ HTTCPPGQRV
160 170 180 190 200
EKRGTHDQDT VCADCLTGTF SLGGTQEECL PWTNCSAFQQ EVRRGTNSTD
210 220 230 240 250
TTCSSQVVYY VVSILLPLVI VGAGIAGFLI CTRRHLHTSS VAKELEPFQE
260 270
QQENTIRFPV TEVGFAETEE ETASN
Length:275
Mass (Da):30,171
Last modified:June 1, 2003 - v1
Checksum:iC4A7EAD8EFC0521D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX004788 Genomic DNA. No translation available.
AY264405 mRNA. Translation: AAO89081.1.
RefSeqiNP_849262.1. NM_178931.2.
XP_006538894.1. XM_006538831.1.
UniGeneiMm.215147.

Genome annotation databases

EnsembliENSMUST00000045919; ENSMUSP00000045240; ENSMUSG00000042333.
ENSMUST00000123514; ENSMUSP00000116757; ENSMUSG00000042333.
GeneIDi230979.
KEGGimmu:230979.
UCSCiuc008wcj.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX004788 Genomic DNA. No translation available.
AY264405 mRNA. Translation: AAO89081.1 .
RefSeqi NP_849262.1. NM_178931.2.
XP_006538894.1. XM_006538831.1.
UniGenei Mm.215147.

3D structure databases

SMRi Q80WM9. Positions 40-205.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

IntActi Q80WM9. 2 interactions.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000045919 ; ENSMUSP00000045240 ; ENSMUSG00000042333 .
ENSMUST00000123514 ; ENSMUSP00000116757 ; ENSMUSG00000042333 .
GeneIDi 230979.
KEGGi mmu:230979.
UCSCi uc008wcj.1. mouse.

Organism-specific databases

CTDi 8764.
MGIi MGI:2675303. Tnfrsf14.

Phylogenomic databases

GeneTreei ENSGT00760000119204.
HOVERGENi HBG072084.
KOi K05152.
OMAi KEACGEL.
PhylomeDBi Q80WM9.
TreeFami TF331157.

Enzyme and pathway databases

Reactomei REACT_225477. Costimulation by the CD28 family.

Miscellaneous databases

NextBioi 380338.
PROi Q80WM9.
SOURCEi Search...

Gene expression databases

Genevestigatori Q80WM9.

Family and domain databases

InterProi IPR001368. TNFR/NGFR_Cys_rich_reg.
IPR022332. TNFR_14.
[Graphical view ]
Pfami PF00020. TNFR_c6. 1 hit.
[Graphical view ]
PRINTSi PR01965. TNFACTORR14.
SMARTi SM00208. TNFR. 4 hits.
[Graphical view ]
PROSITEi PS00652. TNFR_NGFR_1. 1 hit.
PS50050. TNFR_NGFR_2. 3 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Light regulation in a murine model of ovarian carcinoma."
    Benencia F., Conejo-Garcia J.R., Courreges M.C., Coukos G.
    Submitted (MAR-2003) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6Imported.
    Tissue: ThymusImported.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  3. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiQ80WM9_MOUSE
AccessioniPrimary (citable) accession number: Q80WM9
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: June 1, 2003
Last modified: January 7, 2015
This is version 91 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.