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Q80WM9

- Q80WM9_MOUSE

UniProt

Q80WM9 - Q80WM9_MOUSE

Protein
Submitted name:

Protein Tnfrsf14

Gene

Tnfrsf14

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 88 (01 Oct 2014)
      Sequence version 1 (01 Jun 2003)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. protein binding Source: MGI

    GO - Biological processi

    1. defense response to Gram-negative bacterium Source: MGI
    2. defense response to Gram-positive bacterium Source: MGI
    3. negative regulation of alpha-beta T cell proliferation Source: MGI
    4. positive regulation of cytokine secretion involved in immune response Source: MGI
    5. positive regulation of peptidyl-tyrosine phosphorylation Source: MGI
    6. positive regulation of T cell migration Source: MGI

    Keywords - Molecular functioni

    ReceptorImported

    Enzyme and pathway databases

    ReactomeiREACT_225477. Costimulation by the CD28 family.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Protein Tnfrsf14Imported
    Submitted name:
    Tumor necrosis factor receptor superfamily member 14Imported
    Gene namesi
    Name:Tnfrsf14Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 4

    Organism-specific databases

    MGIiMGI:2675303. Tnfrsf14.

    Subcellular locationi

    GO - Cellular componenti

    1. external side of plasma membrane Source: MGI

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 3838 PotentialImportedAdd
    BLAST
    Chaini39 – 275237 PotentialImportedPRO_5000090558Add
    BLAST

    Expressioni

    Gene expression databases

    GenevestigatoriQ80WM9.

    Family & Domainsi

    Keywords - Domaini

    SignalImported

    Phylogenomic databases

    GeneTreeiENSGT00740000115191.
    HOVERGENiHBG072084.
    InParanoidiQ80WM9.
    KOiK05152.
    OMAiSPGHFCI.
    TreeFamiTF331157.

    Family and domain databases

    InterProiIPR001368. TNFR/NGFR_Cys_rich_reg.
    IPR022332. TNFR_14.
    [Graphical view]
    PfamiPF00020. TNFR_c6. 1 hit.
    [Graphical view]
    PRINTSiPR01965. TNFACTORR14.
    SMARTiSM00208. TNFR. 4 hits.
    [Graphical view]
    PROSITEiPS00652. TNFR_NGFR_1. 1 hit.
    PS50050. TNFR_NGFR_2. 3 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q80WM9-1 [UniParc]FASTAAdd to Basket

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    MEPLPGWGSA PWSQAPTDNT FRLVPCVFLL NLLQRISAQP SCRQEEFLVG    50
    DECCPMCNPG YHVKQVCSEH TGTVCAPCPP QTYTAHANGL SKCLPCGVCD 100
    PDMGLLTWQE CSSWKDTVCR CIPGYFCENQ DGSHCSTCLQ HTTCPPGQRV 150
    EKRGTHDQDT VCADCLTGTF SLGGTQEECL PWTNCSAFQQ EVRRGTNSTD 200
    TTCSSQVVYY VVSILLPLVI VGAGIAGFLI CTRRHLHTSS VAKELEPFQE 250
    QQENTIRFPV TEVGFAETEE ETASN 275
    Length:275
    Mass (Da):30,171
    Last modified:June 1, 2003 - v1
    Checksum:iC4A7EAD8EFC0521D
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BX004788 Genomic DNA. No translation available.
    AY264405 mRNA. Translation: AAO89081.1.
    RefSeqiNP_849262.1. NM_178931.2.
    XP_006538894.1. XM_006538831.1.
    UniGeneiMm.215147.

    Genome annotation databases

    EnsembliENSMUST00000045919; ENSMUSP00000045240; ENSMUSG00000042333.
    ENSMUST00000123514; ENSMUSP00000116757; ENSMUSG00000042333.
    GeneIDi230979.
    KEGGimmu:230979.
    UCSCiuc008wcj.1. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BX004788 Genomic DNA. No translation available.
    AY264405 mRNA. Translation: AAO89081.1 .
    RefSeqi NP_849262.1. NM_178931.2.
    XP_006538894.1. XM_006538831.1.
    UniGenei Mm.215147.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000045919 ; ENSMUSP00000045240 ; ENSMUSG00000042333 .
    ENSMUST00000123514 ; ENSMUSP00000116757 ; ENSMUSG00000042333 .
    GeneIDi 230979.
    KEGGi mmu:230979.
    UCSCi uc008wcj.1. mouse.

    Organism-specific databases

    CTDi 8764.
    MGIi MGI:2675303. Tnfrsf14.

    Phylogenomic databases

    GeneTreei ENSGT00740000115191.
    HOVERGENi HBG072084.
    InParanoidi Q80WM9.
    KOi K05152.
    OMAi SPGHFCI.
    TreeFami TF331157.

    Enzyme and pathway databases

    Reactomei REACT_225477. Costimulation by the CD28 family.

    Miscellaneous databases

    NextBioi 380338.
    PROi Q80WM9.
    SOURCEi Search...

    Gene expression databases

    Genevestigatori Q80WM9.

    Family and domain databases

    InterProi IPR001368. TNFR/NGFR_Cys_rich_reg.
    IPR022332. TNFR_14.
    [Graphical view ]
    Pfami PF00020. TNFR_c6. 1 hit.
    [Graphical view ]
    PRINTSi PR01965. TNFACTORR14.
    SMARTi SM00208. TNFR. 4 hits.
    [Graphical view ]
    PROSITEi PS00652. TNFR_NGFR_1. 1 hit.
    PS50050. TNFR_NGFR_2. 3 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Light regulation in a murine model of ovarian carcinoma."
      Benencia F., Conejo-Garcia J.R., Courreges M.C., Coukos G.
      Submitted (MAR-2003) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6Imported.
      Tissue: ThymusImported.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6JImported.
    3. Ensembl
      Submitted (FEB-2012) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.

    Entry informationi

    Entry nameiQ80WM9_MOUSE
    AccessioniPrimary (citable) accession number: Q80WM9
    Entry historyi
    Integrated into UniProtKB/TrEMBL: June 1, 2003
    Last sequence update: June 1, 2003
    Last modified: October 1, 2014
    This is version 88 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3