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Q80WM6

- Q80WM6_RAT

UniProt

Q80WM6 - Q80WM6_RAT

Protein
Submitted name:

2',5'-oligoisoadenylate synthetase-dependent ribonuclease L

Gene

Rnasel

Organism
Rattus norvegicus (Rat)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 88 (01 Oct 2014)
      Sequence version 1 (01 Jun 2003)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. ATP binding Source: InterPro
    2. protein kinase activity Source: InterPro
    3. ribonuclease activity Source: RGD
    4. rRNA binding Source: RGD

    GO - Biological processi

    1. mRNA processing Source: InterPro
    2. RNA phosphodiester bond hydrolysis Source: GOC
    3. rRNA processing Source: RGD

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    2',5'-oligoisoadenylate synthetase-dependent ribonuclease LImported
    Gene namesi
    Name:RnaselImported
    OrganismiRattus norvegicus (Rat)Imported
    Taxonomic identifieri10116 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

    Organism-specific databases

    RGDi727933. Rnasel.

    Subcellular locationi

    GO - Cellular componenti

    1. nuclear matrix Source: RGD

    Expressioni

    Gene expression databases

    GenevestigatoriQ80WM6.

    Interactioni

    Protein-protein interaction databases

    STRINGi10116.ENSRNOP00000032975.

    Structurei

    3D structure databases

    ProteinModelPortaliQ80WM6.
    SMRiQ80WM6. Positions 24-309.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Contains 8 ANK repeats.UniRule annotation

    Keywords - Domaini

    ANK repeatUniRule annotation, RepeatUniRule annotation

    Phylogenomic databases

    eggNOGiCOG0666.
    HOGENOMiHOG000276879.
    HOVERGENiHBG012673.
    InParanoidiQ80WM6.
    KOiK01165.
    PhylomeDBiQ80WM6.

    Family and domain databases

    Gene3Di1.25.40.20. 1 hit.
    InterProiIPR002110. Ankyrin_rpt.
    IPR020683. Ankyrin_rpt-contain_dom.
    IPR010513. KEN_dom.
    IPR011009. Kinase-like_dom.
    IPR000719. Prot_kinase_dom.
    IPR006567. PUG-dom.
    [Graphical view]
    PfamiPF12796. Ank_2. 3 hits.
    PF00069. Pkinase. 1 hit.
    PF06479. Ribonuc_2-5A. 1 hit.
    [Graphical view]
    PRINTSiPR01415. ANKYRIN.
    SMARTiSM00248. ANK. 8 hits.
    SM00580. PUG. 1 hit.
    [Graphical view]
    SUPFAMiSSF48403. SSF48403. 1 hit.
    SSF56112. SSF56112. 1 hit.
    PROSITEiPS50297. ANK_REP_REGION. 1 hit.
    PS50088. ANK_REPEAT. 5 hits.
    PS51392. KEN. 1 hit.
    PS50011. PROTEIN_KINASE_DOM. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q80WM6-1 [UniParc]FASTAAdd to Basket

    « Hide

    METTDHSTPQ CGSASAGGQK TVGKDDYLLI EAVNKGDADR VQQLLEQGAD    50
    ANVCEESGGW TPLHNAVQSG RVDIVNLLLR YGADPHRRKK NGATPFIVAG 100
    ICGDVSLLQI FLSRGANINE RDMYGFTAFM EAAEYGNVEA LKFLFAEGAD 150
    VNLRRETTED RRRLKQGGAT ALMSAAENGH PEVVRILLDE MKAEADARDN 200
    MGRNALIRSL LNRDCENVEI HVEEITSVLI QYGADINVRG EGEKTPLISA 250
    VKRKHTGLVQ MLLSQEGIKV NDRDSEGKTA LQIAVELKLK EIVRLLLEKG 300
    ADTKCGDLVW IAKRNYDHGL VKLLLSYEAN HDTNPPAKDW LPHSARWGEA 350
    LERLHSVSRP MTGKLKIFMN DDYKIASTSE GGIYLGIYDN REVAVKVFCE 400
    NSSRGRKEVS CLRDCGDHSN LLTFYGSEEH KGSLYVCVSL CESTLEKFLN 450
    VPREEPMEKG EDKFALSVLL SIFKGVQKLH MHGYSHQNLQ PPNILIDSEK 500
    AVRLADFDES IQWMRESQTV QRDLEDLGRL VLYVVNKGEI PFETLKGQND 550
    EELLTIAPNE ETKDLVHCLF SPGENVKNCL MDLLGHPFFW TWENRYRTLR 600
    DVGNESDIKV RNNKSKLLKL LQPQTHAPSR SFDRWTSKID KRVMSDMNGF 650
    YKSRKGYRDT VGDLLKFIRN IGEHINEEKN RQMKEILGDP SRYFQETFPD 700
    LVIYIYKKLK ETEFRKHFPQ PPPSLSVPEA AGPGGVQS 738
    Length:738
    Mass (Da):83,210
    Last modified:June 1, 2003 - v1
    Checksum:i2A288A114C5FE633
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY262823 mRNA. Translation: AAP22025.1.
    RefSeqiNP_872614.1. NM_182673.2.
    UniGeneiRn.107928.
    Rn.228575.

    Genome annotation databases

    GeneIDi359726.
    KEGGirno:359726.
    UCSCiRGD:727933. rat.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY262823 mRNA. Translation: AAP22025.1 .
    RefSeqi NP_872614.1. NM_182673.2.
    UniGenei Rn.107928.
    Rn.228575.

    3D structure databases

    ProteinModelPortali Q80WM6.
    SMRi Q80WM6. Positions 24-309.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 10116.ENSRNOP00000032975.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 359726.
    KEGGi rno:359726.
    UCSCi RGD:727933. rat.

    Organism-specific databases

    CTDi 6041.
    RGDi 727933. Rnasel.

    Phylogenomic databases

    eggNOGi COG0666.
    HOGENOMi HOG000276879.
    HOVERGENi HBG012673.
    InParanoidi Q80WM6.
    KOi K01165.
    PhylomeDBi Q80WM6.

    Miscellaneous databases

    NextBioi 672697.

    Gene expression databases

    Genevestigatori Q80WM6.

    Family and domain databases

    Gene3Di 1.25.40.20. 1 hit.
    InterProi IPR002110. Ankyrin_rpt.
    IPR020683. Ankyrin_rpt-contain_dom.
    IPR010513. KEN_dom.
    IPR011009. Kinase-like_dom.
    IPR000719. Prot_kinase_dom.
    IPR006567. PUG-dom.
    [Graphical view ]
    Pfami PF12796. Ank_2. 3 hits.
    PF00069. Pkinase. 1 hit.
    PF06479. Ribonuc_2-5A. 1 hit.
    [Graphical view ]
    PRINTSi PR01415. ANKYRIN.
    SMARTi SM00248. ANK. 8 hits.
    SM00580. PUG. 1 hit.
    [Graphical view ]
    SUPFAMi SSF48403. SSF48403. 1 hit.
    SSF56112. SSF56112. 1 hit.
    PROSITEi PS50297. ANK_REP_REGION. 1 hit.
    PS50088. ANK_REPEAT. 5 hits.
    PS51392. KEN. 1 hit.
    PS50011. PROTEIN_KINASE_DOM. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Molecular cloning of the rat RNaseL gene."
      Hummer B.T., Hassel B.A.
      Submitted (MAR-2003) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.

    Entry informationi

    Entry nameiQ80WM6_RAT
    AccessioniPrimary (citable) accession number: Q80WM6
    Entry historyi
    Integrated into UniProtKB/TrEMBL: June 1, 2003
    Last sequence update: June 1, 2003
    Last modified: October 1, 2014
    This is version 88 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)