Q80WM6 (Q80WM6_RAT) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
2',5'-oligoisoadenylate synthetase-dependent ribonuclease L EMBL AAP22025.1

Gene names

Name:

Rnasel RGD 727933

Organism

Rattus norvegicus (Rat) EMBL AAP22025.1

Taxonomic identifier

10116 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Rattus

Protein attributes

Sequence length	738 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Domain	ANK repeat RuleBase RU003321 Repeat RuleBase RU003536
Gene Ontology (GO)
Biological_process	mRNA processing Inferred from electronic annotation. Source: InterPro rRNA processing Inferred from direct assay PubMed 8469023. Source: RGD
Cellular_component	nuclear matrix Inferred from direct assay PubMed 8469023. Source: RGD
Molecular_function	ATP binding Inferred from electronic annotation. Source: InterPro protein kinase activity Inferred from electronic annotation. Source: InterPro rRNA binding Inferred from direct assay PubMed 8469023. Source: RGD ribonuclease activity Inferred from direct assay PubMed 8469023. Source: RGD
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q80WM6 [UniParc]. Last modified June 1, 2003. Version 1. Checksum: 2A288A114C5FE633	FASTA	738	83,210
	10 20 30 40 50 60 METTDHSTPQ CGSASAGGQK TVGKDDYLLI EAVNKGDADR VQQLLEQGAD ANVCEESGGW 70 80 90 100 110 120 TPLHNAVQSG RVDIVNLLLR YGADPHRRKK NGATPFIVAG ICGDVSLLQI FLSRGANINE 130 140 150 160 170 180 RDMYGFTAFM EAAEYGNVEA LKFLFAEGAD VNLRRETTED RRRLKQGGAT ALMSAAENGH 190 200 210 220 230 240 PEVVRILLDE MKAEADARDN MGRNALIRSL LNRDCENVEI HVEEITSVLI QYGADINVRG 250 260 270 280 290 300 EGEKTPLISA VKRKHTGLVQ MLLSQEGIKV NDRDSEGKTA LQIAVELKLK EIVRLLLEKG 310 320 330 340 350 360 ADTKCGDLVW IAKRNYDHGL VKLLLSYEAN HDTNPPAKDW LPHSARWGEA LERLHSVSRP 370 380 390 400 410 420 MTGKLKIFMN DDYKIASTSE GGIYLGIYDN REVAVKVFCE NSSRGRKEVS CLRDCGDHSN 430 440 450 460 470 480 LLTFYGSEEH KGSLYVCVSL CESTLEKFLN VPREEPMEKG EDKFALSVLL SIFKGVQKLH 490 500 510 520 530 540 MHGYSHQNLQ PPNILIDSEK AVRLADFDES IQWMRESQTV QRDLEDLGRL VLYVVNKGEI 550 560 570 580 590 600 PFETLKGQND EELLTIAPNE ETKDLVHCLF SPGENVKNCL MDLLGHPFFW TWENRYRTLR 610 620 630 640 650 660 DVGNESDIKV RNNKSKLLKL LQPQTHAPSR SFDRWTSKID KRVMSDMNGF YKSRKGYRDT 670 680 690 700 710 720 VGDLLKFIRN IGEHINEEKN RQMKEILGDP SRYFQETFPD LVIYIYKKLK ETEFRKHFPQ 730 PPPSLSVPEA AGPGGVQS

References

[1]	"Molecular cloning of the rat RNaseL gene." Hummer B.T., Hassel B.A. Submitted (MAR-2003) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AY262823 mRNA. Translation: AAP22025.1.
IPI	IPI00331894.
RefSeq	NP_872614.1. NM_182673.2.
UniGene	Rn.228575.
3D structure databases
ProteinModelPortal	Q80WM6.
SMR	Q80WM6. Positions 24-309.
ModBase	Search...
Protein-protein interaction databases
STRING	10116.ENSRNOP00000032975.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	359726.
KEGG	rno:359726.
UCSC	RGD:727933. rat.
Organism-specific databases
CTD	6041.
RGD	727933. Rnasel.
Phylogenomic databases
eggNOG	COG0666.
HOGENOM	HOG000276879.
HOVERGEN	HBG012673.
InParanoid	Q80WM6.
KO	K01165.
OrthoDB	EOG479F6R.
Gene expression databases
Genevestigator	Q80WM6.
Family and domain databases
Gene3D	1.25.40.20. 1 hit.
InterPro	IPR002110. Ankyrin_rpt. IPR020683. Ankyrin_rpt-contain_dom. IPR010513. KEN_dom. IPR011009. Kinase-like_dom. IPR000719. Prot_kinase_cat_dom. IPR006567. PUG-dom. [Graphical view]
Pfam	PF00023. Ank. 1 hit. PF12796. Ank_2. 3 hits. PF00069. Pkinase. 1 hit. PF06479. Ribonuc_2-5A. 1 hit. [Graphical view]
PRINTS	PR01415. ANKYRIN.
SMART	SM00248. ANK. 8 hits. SM00580. PUG. 1 hit. [Graphical view]
SUPFAM	SSF48403. ANK. 1 hit. SSF56112. Kinase_like. 1 hit.
PROSITE	PS50297. ANK_REP_REGION. 1 hit. PS50088. ANK_REPEAT. 5 hits. PS51392. KEN. 1 hit. PS50011. PROTEIN_KINASE_DOM. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	672697.

Entry information

Entry name

Q80WM6_RAT

Accession

Primary (citable) accession number: Q80WM6

Entry history

Integrated into UniProtKB/TrEMBL:	June 1, 2003
Last sequence update:	June 1, 2003
Last modified:	May 29, 2013
This is version 78 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)