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Protein

NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11

Gene

Ndufa11

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.By similarity

GO - Biological processi

Keywordsi

Biological processElectron transport, Respiratory chain, Transport

Enzyme and pathway databases

ReactomeiR-RNO-611105 Respiratory electron transport
R-RNO-6799198 Complex I biogenesis

Names & Taxonomyi

Protein namesi
Recommended name:
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11
Alternative name(s):
Complex I-B14.7
Short name:
CI-B14.7
NADH-ubiquinone oxidoreductase subunit B14.7
Gene namesi
Name:Ndufa11
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 9

Organism-specific databases

RGDi1303292 Ndufa11

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei21 – 43HelicalSequence analysisAdd BLAST23
Transmembranei58 – 80HelicalSequence analysisAdd BLAST23

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedBy similarity
ChainiPRO_00001188432 – 141NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11Add BLAST140

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei2N-acetylalanineBy similarity1

Keywords - PTMi

Acetylation

Proteomic databases

PaxDbiQ80W89
PRIDEiQ80W89

PTM databases

iPTMnetiQ80W89

Expressioni

Gene expression databases

BgeeiENSRNOG00000048320
GenevisibleiQ80W89 RN

Interactioni

Subunit structurei

Complex I is composed of 45 different subunits.By similarity

Protein-protein interaction databases

BioGridi256851, 1 interactor
STRINGi10116.ENSRNOP00000064246

Structurei

3D structure databases

SMRiQ80W89
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the complex I NDUFA11 subunit family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410IYXZ Eukaryota
ENOG4111P1Q LUCA
GeneTreeiENSGT00390000012434
HOVERGENiHBG052568
InParanoidiQ80W89
KOiK03956
OMAiFAYNTGP
OrthoDBiEOG091G0SEB
PhylomeDBiQ80W89

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q80W89-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKRFFEAYN ETPDGTQCHR KAYITTALGG LCGLISSAYS ITHNPADSPL
60 70 80 90 100
EAVARVGRFT FTAAAIGAMF GLTTCVSAQV REKPDDPLNY FIGGCAGGLT
110 120 130 140
LGARTHSYGT AAIGCVYMGT AAALFKMGKL EGWELFATPK V
Length:141
Mass (Da):14,854
Last modified:June 1, 2003 - v1
Checksum:i39377612BFC67A12
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY272059 mRNA Translation: AAP32478.1
RefSeqiNP_997682.1, NM_212517.1
UniGeneiRn.96380

Genome annotation databases

EnsembliENSRNOT00000070862; ENSRNOP00000064246; ENSRNOG00000048320
GeneIDi301123
KEGGirno:301123

Similar proteinsi

Entry informationi

Entry nameiNDUAB_RAT
AccessioniPrimary (citable) accession number: Q80W89
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 13, 2004
Last sequence update: June 1, 2003
Last modified: May 23, 2018
This is version 88 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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