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Protein

NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11

Gene

Ndufa11

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).By similarity

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Electron transport, Respiratory chain, Transport

Enzyme and pathway databases

ReactomeiR-RNO-611105. Respiratory electron transport.
R-RNO-6799198. Complex I biogenesis.

Names & Taxonomyi

Protein namesi
Recommended name:
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11
Alternative name(s):
Complex I-B14.7
Short name:
CI-B14.7
NADH-ubiquinone oxidoreductase subunit B14.7
Gene namesi
Name:Ndufa11
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 9

Organism-specific databases

RGDi1303292. Ndufa11.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei21 – 43HelicalSequence analysisAdd BLAST23
Transmembranei58 – 80HelicalSequence analysisAdd BLAST23

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedBy similarity
ChainiPRO_00001188432 – 141NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11Add BLAST140

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei2N-acetylalanineBy similarity1

Keywords - PTMi

Acetylation

Proteomic databases

PaxDbiQ80W89.
PRIDEiQ80W89.

Expressioni

Gene expression databases

BgeeiENSRNOG00000048320.
GenevisibleiQ80W89. RN.

Interactioni

Subunit structurei

Complex I is composed of 45 different subunits.By similarity

Protein-protein interaction databases

MINTiMINT-4997607.
STRINGi10116.ENSRNOP00000064246.

Family & Domainsi

Sequence similaritiesi

Belongs to the complex I NDUFA11 subunit family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410IYXZ. Eukaryota.
ENOG4111P1Q. LUCA.
GeneTreeiENSGT00390000012434.
HOVERGENiHBG052568.
InParanoidiQ80W89.
KOiK03956.
OMAiFLGARTH.
OrthoDBiEOG091G0SEB.
PhylomeDBiQ80W89.

Family and domain databases

InterProiIPR003397. Tim17/Tim22/Tim23/PMP24.
[Graphical view]
PfamiPF02466. Tim17. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q80W89-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKRFFEAYN ETPDGTQCHR KAYITTALGG LCGLISSAYS ITHNPADSPL
60 70 80 90 100
EAVARVGRFT FTAAAIGAMF GLTTCVSAQV REKPDDPLNY FIGGCAGGLT
110 120 130 140
LGARTHSYGT AAIGCVYMGT AAALFKMGKL EGWELFATPK V
Length:141
Mass (Da):14,854
Last modified:June 1, 2003 - v1
Checksum:i39377612BFC67A12
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY272059 mRNA. Translation: AAP32478.1.
RefSeqiNP_997682.1. NM_212517.1.
UniGeneiRn.96380.

Genome annotation databases

EnsembliENSRNOT00000070862; ENSRNOP00000064246; ENSRNOG00000048320.
GeneIDi301123.
KEGGirno:301123.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY272059 mRNA. Translation: AAP32478.1.
RefSeqiNP_997682.1. NM_212517.1.
UniGeneiRn.96380.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

MINTiMINT-4997607.
STRINGi10116.ENSRNOP00000064246.

Proteomic databases

PaxDbiQ80W89.
PRIDEiQ80W89.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000070862; ENSRNOP00000064246; ENSRNOG00000048320.
GeneIDi301123.
KEGGirno:301123.

Organism-specific databases

CTDi126328.
RGDi1303292. Ndufa11.

Phylogenomic databases

eggNOGiENOG410IYXZ. Eukaryota.
ENOG4111P1Q. LUCA.
GeneTreeiENSGT00390000012434.
HOVERGENiHBG052568.
InParanoidiQ80W89.
KOiK03956.
OMAiFLGARTH.
OrthoDBiEOG091G0SEB.
PhylomeDBiQ80W89.

Enzyme and pathway databases

ReactomeiR-RNO-611105. Respiratory electron transport.
R-RNO-6799198. Complex I biogenesis.

Miscellaneous databases

PROiQ80W89.

Gene expression databases

BgeeiENSRNOG00000048320.
GenevisibleiQ80W89. RN.

Family and domain databases

InterProiIPR003397. Tim17/Tim22/Tim23/PMP24.
[Graphical view]
PfamiPF02466. Tim17. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiNDUAB_RAT
AccessioniPrimary (citable) accession number: Q80W89
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 13, 2004
Last sequence update: June 1, 2003
Last modified: September 7, 2016
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.