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Protein
Submitted name:

Ptpro protein

Gene

Ptpro

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei428Phosphocysteine intermediatePROSITE-ProRule annotation1

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
Ptpro proteinImported
Gene namesi
Name:PtproImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1097152. Ptpro.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei112 – 136HelicalSequence analysisAdd BLAST25
Transmembranei172 – 193HelicalSequence analysisAdd BLAST22

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiQ80W11.

Structurei

3D structure databases

ProteinModelPortaliQ80W11.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini17 – 109Fibronectin type-IIIInterPro annotationAdd BLAST93
Domaini230 – 487Tyrosine-protein phosphataseInterPro annotationAdd BLAST258
Domaini404 – 478TYR_PHOSPHATASE_2InterPro annotationAdd BLAST75

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG0791. Eukaryota.
COG5599. LUCA.
HOVERGENiHBG053969.

Family and domain databases

CDDicd00063. FN3. 1 hit.
Gene3Di2.60.40.10. 1 hit.
3.90.190.10. 1 hit.
InterProiView protein in InterPro
IPR003961. FN3_dom.
IPR013783. Ig-like_fold.
IPR029021. Prot-tyrosine_phosphatase-like.
IPR000242. PTPase_domain.
IPR016130. Tyr_Pase_AS.
IPR003595. Tyr_Pase_cat.
IPR000387. TYR_PHOSPHATASE_dom.
PfamiView protein in Pfam
PF00041. fn3. 1 hit.
PF00102. Y_phosphatase. 1 hit.
PRINTSiPR00700. PRTYPHPHTASE.
SMARTiView protein in SMART
SM00060. FN3. 1 hit.
SM00194. PTPc. 1 hit.
SM00404. PTPc_motif. 1 hit.
SUPFAMiSSF49265. SSF49265. 1 hit.
SSF52799. SSF52799. 1 hit.
PROSITEiView protein in PROSITE
PS50853. FN3. 1 hit.
PS00383. TYR_PHOSPHATASE_1. 1 hit.
PS50056. TYR_PHOSPHATASE_2. 1 hit.
PS50055. TYR_PHOSPHATASE_PTP. 1 hit.

Sequencei

Sequence statusi: Fragment.

Q80W11-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
RGSNTSLPRL VKLEPAPPKS LFAVNKTQTS VTLLWVEEGV ADFFEVFCQQ
60 70 80 90 100
LGSGHNGKLQ EPVAVSSHVV TISSLLPATA YNCSVTSFSH DTPSVPTFIA
110 120 130 140 150
VSTMVTEVNP NVVVISVLAI LSTLLIGLLL VTLVILRKKH LQMARECGAG
160 170 180 190 200
TFVNFASLER EGKLPYSWRR SVFALLTLLP SCLWTDYLLA FYINPWSKNG
210 220 230 240 250
LKKRKLTNPV QLDDFDSYIK DMAKDSDYKF SLQFEELKLI GLDIPHFAAD
260 270 280 290 300
LPLNRCKNRY TNILPYDFSR VRLVSMNEEE GADYINANYI PGYNSPQEYI
310 320 330 340 350
ATQGPLPETR NDFWKMVLQQ KSHIIVMLTQ CNEKRRVKCD HYWPFTEEPI
360 370 380 390 400
AYGDITVEMV SEEEEEDWAS RHFRINYADE AQDVMHFNYT AWPDHGVPPA
410 420 430 440 450
NAAESILQFV FTVRQQAAKS KGPMIIHCSA GVGRTGTFIA LDRLLQHIRD
460 470 480 490 500
HEFVDILGLV SEMRSYRMSM VQTEEQYIFI HQCVQLMWLR KKQQFCISDV

IYENVSKS
Length:508
Mass (Da):57,919
Last modified:June 1, 2003 - v1
Checksum:i2080CA6AE4B06024
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC051976 mRNA. Translation: AAH51976.1.
UniGeneiMm.186361.
Mm.491536.

Similar proteinsi

Entry informationi

Entry nameiQ80W11_MOUSE
AccessioniPrimary (citable) accession number: Q80W11
Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: June 1, 2003
Last modified: August 30, 2017
This is version 101 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)