##gff-version 3
Q80VM9	UniProtKB	Chain	1	600	.	.	.	ID=PRO_0000313817;Note=Proton channel OTOP1	
Q80VM9	UniProtKB	Transmembrane	65	85	.	.	.	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q80VM9	UniProtKB	Transmembrane	90	110	.	.	.	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q80VM9	UniProtKB	Transmembrane	135	155	.	.	.	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q80VM9	UniProtKB	Transmembrane	166	186	.	.	.	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q80VM9	UniProtKB	Transmembrane	199	219	.	.	.	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q80VM9	UniProtKB	Transmembrane	267	287	.	.	.	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q80VM9	UniProtKB	Transmembrane	309	329	.	.	.	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q80VM9	UniProtKB	Transmembrane	345	365	.	.	.	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q80VM9	UniProtKB	Transmembrane	391	411	.	.	.	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q80VM9	UniProtKB	Transmembrane	422	442	.	.	.	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q80VM9	UniProtKB	Transmembrane	533	553	.	.	.	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q80VM9	UniProtKB	Transmembrane	564	584	.	.	.	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q80VM9	UniProtKB	Region	1	50	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q80VM9	UniProtKB	Alternative sequence	1	190	.	.	.	ID=VSP_030160;Note=In isoform 2. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:16141072;Dbxref=PMID:16141072	
Q80VM9	UniProtKB	Alternative sequence	1	35	.	.	.	ID=VSP_030161;Note=In isoform 3. MPGGPGAPSSPAASSGSSRAAPSGIAACPLSPPPL->MLTPPETLSAFLAGGFLGCLCLLEGLGCLRIA;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:12651873;Dbxref=PMID:12651873	
Q80VM9	UniProtKB	Mutagenesis	151	151	.	.	.	Note=In tlt (tilted phenotype)%3B affected mice have defects in the formation of otoconia in the inner ear%2C but do not suffer from deafness or other inner ear defects. They cannot perceive gravity and have problems with spatial orientation and with keeping their equilibrium. They show typical head-tilting behavior and are unable to swim. Impaired subcellular localization to the plasma membrane. Effects may be due to dysregulation of pH. A->E;Ontology_term=ECO:0000269,ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:12651873,ECO:0000269|PubMed:21236346,ECO:0000269|PubMed:29371428;Dbxref=PMID:12651873,PMID:21236346,PMID:29371428	
Q80VM9	UniProtKB	Mutagenesis	408	408	.	.	.	Note=In mlh (mergulhador phenotype)%3B affected mice have defects in the formation of otoconia in the inner ear%2C but do not suffer from deafness or other inner ear defects. They cannot perceive gravity and have problems with spatial orientation and with keeping their equilibrium. They show typical head-tilting behavior and are unable to swim. Impaired subcellular localization to the plasma membrane. L->Q;Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:12651873,ECO:0000269|PubMed:21236346;Dbxref=PMID:12651873,PMID:21236346	
Q80VM9	UniProtKB	Sequence conflict	396	396	.	.	.	Note=G->A	
Q80VM9	UniProtKB	Sequence conflict	401	401	.	.	.	Note=L->P;Ontology_term=ECO:0000305;evidence=ECO:0000305