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Protein

Zinc finger protein 579

Gene

Znf579

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

May be involved in transcriptional regulation.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri46 – 68C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri74 – 96C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri102 – 125C2H2-type 3PROSITE-ProRule annotationAdd BLAST24
Zinc fingeri267 – 289C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri295 – 317C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri382 – 404C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri410 – 432C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri439 – 461C2H2-type 8PROSITE-ProRule annotationAdd BLAST23

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding, Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Zinc finger protein 579
Gene namesi
Name:Znf579
Synonyms:Zfp579
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 7

Organism-specific databases

MGIiMGI:1915740. Zfp579.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000476701 – 562Zinc finger protein 579Add BLAST562

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei94Omega-N-methylarginineCombined sources1
Modified residuei191PhosphoserineBy similarity1
Modified residuei486PhosphoserineBy similarity1

Keywords - PTMi

Methylation, Phosphoprotein

Proteomic databases

MaxQBiQ80VM4.
PaxDbiQ80VM4.
PRIDEiQ80VM4.

PTM databases

iPTMnetiQ80VM4.
PhosphoSitePlusiQ80VM4.

Expressioni

Gene expression databases

BgeeiENSMUSG00000051550.
CleanExiMM_ZFP579.
ExpressionAtlasiQ80VM4. baseline and differential.
GenevisibleiQ80VM4. MM.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000104212.

Structurei

3D structure databases

ProteinModelPortaliQ80VM4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi328 – 368Gly-richAdd BLAST41
Compositional biasi487 – 525Pro-richAdd BLAST39

Sequence similaritiesi

Contains 8 C2H2-type zinc fingers.PROSITE-ProRule annotation

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri46 – 68C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri74 – 96C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri102 – 125C2H2-type 3PROSITE-ProRule annotationAdd BLAST24
Zinc fingeri267 – 289C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri295 – 317C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri382 – 404C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri410 – 432C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri439 – 461C2H2-type 8PROSITE-ProRule annotationAdd BLAST23

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

eggNOGiKOG1721. Eukaryota.
COG5048. LUCA.
GeneTreeiENSGT00850000132444.
HOGENOMiHOG000054202.
HOVERGENiHBG098620.
InParanoidiQ80VM4.
OMAiQDEGVEQ.
OrthoDBiEOG091G0766.
PhylomeDBiQ80VM4.
TreeFamiTF331849.

Family and domain databases

Gene3Di3.30.160.60. 7 hits.
InterProiIPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
SMARTiSM00355. ZnF_C2H2. 8 hits.
[Graphical view]
PROSITEiPS00028. ZINC_FINGER_C2H2_1. 8 hits.
PS50157. ZINC_FINGER_C2H2_2. 8 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q80VM4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDPQPPPPAQ GSPPHRDRGR GRGRGRGRGR GRGRGRGGAG APRAPLPCPT
60 70 80 90 100
CGRLFRFPYY LSRHRLSHSG LRPHACPLCP KAFRRPAHLS RHLRGHGPQP
110 120 130 140 150
PLRCAACPRT FPEPAQLRRH LAQEHAGSEV DLSTQRAVKE EPEASWGPQD
160 170 180 190 200
EGVEQPATVV VAGAEEEATT QWPAGDSAPA AVPTSTDPRE SEAKEAEAGA
210 220 230 240 250
AELRAELALA AGRQEEKQVL LQADWTLLCL RCREAFATKG ELKAHPCLRP
260 270 280 290 300
EGEQEGEGGP PPRPKRHQCS ICLKAFARPW SLSRHRLVHS TDRPFVCPDC
310 320 330 340 350
GLAFRLASYL RQHRRVHGPL SLLAPLPGAG KKDDKASGGR NSGKGPEGGE
360 370 380 390 400
GAECGGASEG GEGGHNGGDA TPARPPAGEP RFWCPECGKG FRRRAHLRQH
410 420 430 440 450
GVTHSGARPF QCVRCQREFK RLADLARHAQ VHAGGPAPHP CPRCPRRFSR
460 470 480 490 500
AYSLLRHQRC HRAELERAEL ERAAALQELQ TQASQSPQPP QPLKQEAEGL
510 520 530 540 550
PLPIAHIKEE PPSPGTPPQS PPAPPVFLSA SCFDSQDHSA FEMEDEEMDS
560
KAHLCGLGGL AS
Length:562
Mass (Da):60,792
Last modified:June 1, 2003 - v1
Checksum:i788F3DB1627A3419
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC048385 mRNA. Translation: AAH48385.1.
CCDSiCCDS39744.1.
RefSeqiNP_081017.1. NM_026741.2.
XP_006540398.1. XM_006540335.3.
UniGeneiMm.76400.

Genome annotation databases

EnsembliENSMUST00000108572; ENSMUSP00000104212; ENSMUSG00000051550.
ENSMUST00000162731; ENSMUSP00000123963; ENSMUSG00000051550.
GeneIDi68490.
KEGGimmu:68490.
UCSCiuc009ezc.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC048385 mRNA. Translation: AAH48385.1.
CCDSiCCDS39744.1.
RefSeqiNP_081017.1. NM_026741.2.
XP_006540398.1. XM_006540335.3.
UniGeneiMm.76400.

3D structure databases

ProteinModelPortaliQ80VM4.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000104212.

PTM databases

iPTMnetiQ80VM4.
PhosphoSitePlusiQ80VM4.

Proteomic databases

MaxQBiQ80VM4.
PaxDbiQ80VM4.
PRIDEiQ80VM4.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000108572; ENSMUSP00000104212; ENSMUSG00000051550.
ENSMUST00000162731; ENSMUSP00000123963; ENSMUSG00000051550.
GeneIDi68490.
KEGGimmu:68490.
UCSCiuc009ezc.1. mouse.

Organism-specific databases

CTDi68490.
MGIiMGI:1915740. Zfp579.

Phylogenomic databases

eggNOGiKOG1721. Eukaryota.
COG5048. LUCA.
GeneTreeiENSGT00850000132444.
HOGENOMiHOG000054202.
HOVERGENiHBG098620.
InParanoidiQ80VM4.
OMAiQDEGVEQ.
OrthoDBiEOG091G0766.
PhylomeDBiQ80VM4.
TreeFamiTF331849.

Miscellaneous databases

PROiQ80VM4.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000051550.
CleanExiMM_ZFP579.
ExpressionAtlasiQ80VM4. baseline and differential.
GenevisibleiQ80VM4. MM.

Family and domain databases

Gene3Di3.30.160.60. 7 hits.
InterProiIPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
SMARTiSM00355. ZnF_C2H2. 8 hits.
[Graphical view]
PROSITEiPS00028. ZINC_FINGER_C2H2_1. 8 hits.
PS50157. ZINC_FINGER_C2H2_2. 8 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiZN579_MOUSE
AccessioniPrimary (citable) accession number: Q80VM4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 6, 2005
Last sequence update: June 1, 2003
Last modified: November 2, 2016
This is version 113 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.