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Protein

Protein ABHD13

Gene

Abhd13

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei193Charge relay systemBy similarity1
Active sitei268Charge relay systemBy similarity1
Active sitei298Charge relay systemBy similarity1

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Protein family/group databases

ESTHERimouse-Q80UX8. ABHD13-BEM46.
MEROPSiS09.051.

Names & Taxonomyi

Protein namesi
Recommended name:
Protein ABHD13Curated (EC:3.-.-.-)
Alternative name(s):
Alpha/beta hydrolase domain-containing protein 13Curated
Short name:
Abhydrolase domain-containing protein 13Imported
Gene namesi
Name:Abhd13Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 8

Organism-specific databases

MGIiMGI:1916154. Abhd13.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei37 – 57Helical; Signal-anchor for type II membrane proteinSequence analysisAdd BLAST21

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Chemistry databases

ChEMBLiCHEMBL3259493.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002810771 – 337Protein ABHD13Add BLAST337

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi299N-linked (GlcNAc...)Sequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

MaxQBiQ80UX8.
PaxDbiQ80UX8.
PeptideAtlasiQ80UX8.
PRIDEiQ80UX8.

PTM databases

iPTMnetiQ80UX8.
PhosphoSitePlusiQ80UX8.

Expressioni

Gene expression databases

BgeeiENSMUSG00000040396.
CleanExiMM_ABHD13.
GenevisibleiQ80UX8. MM.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000036730.

Structurei

3D structure databases

ProteinModelPortaliQ80UX8.
SMRiQ80UX8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the serine esterase family.Curated

Keywords - Domaini

Signal-anchor, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG4391. Eukaryota.
COG1073. LUCA.
GeneTreeiENSGT00390000000948.
HOGENOMiHOG000007143.
HOVERGENiHBG080816.
InParanoidiQ80UX8.
KOiK06889.
OMAiMGHRLQN.
OrthoDBiEOG091G0FPM.
PhylomeDBiQ80UX8.
TreeFamiTF315122.

Family and domain databases

Gene3Di3.40.50.1820. 1 hit.
InterProiIPR029058. AB_hydrolase.
IPR022742. Hydrolase_4.
[Graphical view]
PfamiPF12146. Hydrolase_4. 1 hit.
[Graphical view]
SUPFAMiSSF53474. SSF53474. 1 hit.

Sequencei

Sequence statusi: Complete.

Q80UX8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEKSWMLWSF IERWLLALAS WSWALCRISL LPLIVTFHLY GGIVLLLLIF
60 70 80 90 100
VSIAGILYKF QDVLLYFPEQ PSSSRLYVPM PTGIPHENIF IRTKDGVRLN
110 120 130 140 150
LILVRYTGDN SPYCPTIIYF HGNAGNIGHR LPNALLMLVN LRVNLVLVDY
160 170 180 190 200
RGYGKSEGEA SEEGLYLDSE AVLDYVMTRP DLDKTKVFLF GRSLGGAVAI
210 220 230 240 250
HLASENSHRI SAIMVENTFL SIPHMASTLF SFFPMRYLPL WCYKNKFLSY
260 270 280 290 300
RKISQCRMPS LFISGLSDQL IPPVMMKQLY ELSPSRTKRL AIFPDGTHND
310 320 330
TWQCQGYFTA LEQFIKEVIK SHSPEDMTKT SSNVTII
Length:337
Mass (Da):38,525
Last modified:June 1, 2003 - v1
Checksum:i0EAA241B44567B09
GO

Sequence cautioni

The sequence BAC31905 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK004375 mRNA. Translation: BAB23280.2.
AK044407 mRNA. Translation: BAC31905.1. Different initiation.
BC043690 mRNA. Translation: AAH43690.1.
CCDSiCCDS40217.1.
RefSeqiNP_001074588.1. NM_001081119.1.
NP_081144.1. NM_026868.1.
UniGeneiMm.142570.
Mm.395885.

Genome annotation databases

EnsembliENSMUST00000048216; ENSMUSP00000036730; ENSMUSG00000040396.
ENSMUST00000139793; ENSMUSP00000116130; ENSMUSG00000040396.
GeneIDi68904.
KEGGimmu:68904.
UCSCiuc009kum.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK004375 mRNA. Translation: BAB23280.2.
AK044407 mRNA. Translation: BAC31905.1. Different initiation.
BC043690 mRNA. Translation: AAH43690.1.
CCDSiCCDS40217.1.
RefSeqiNP_001074588.1. NM_001081119.1.
NP_081144.1. NM_026868.1.
UniGeneiMm.142570.
Mm.395885.

3D structure databases

ProteinModelPortaliQ80UX8.
SMRiQ80UX8.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000036730.

Chemistry databases

ChEMBLiCHEMBL3259493.

Protein family/group databases

ESTHERimouse-Q80UX8. ABHD13-BEM46.
MEROPSiS09.051.

PTM databases

iPTMnetiQ80UX8.
PhosphoSitePlusiQ80UX8.

Proteomic databases

MaxQBiQ80UX8.
PaxDbiQ80UX8.
PeptideAtlasiQ80UX8.
PRIDEiQ80UX8.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000048216; ENSMUSP00000036730; ENSMUSG00000040396.
ENSMUST00000139793; ENSMUSP00000116130; ENSMUSG00000040396.
GeneIDi68904.
KEGGimmu:68904.
UCSCiuc009kum.1. mouse.

Organism-specific databases

CTDi84945.
MGIiMGI:1916154. Abhd13.

Phylogenomic databases

eggNOGiKOG4391. Eukaryota.
COG1073. LUCA.
GeneTreeiENSGT00390000000948.
HOGENOMiHOG000007143.
HOVERGENiHBG080816.
InParanoidiQ80UX8.
KOiK06889.
OMAiMGHRLQN.
OrthoDBiEOG091G0FPM.
PhylomeDBiQ80UX8.
TreeFamiTF315122.

Miscellaneous databases

ChiTaRSiAbhd13. mouse.
PROiQ80UX8.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000040396.
CleanExiMM_ABHD13.
GenevisibleiQ80UX8. MM.

Family and domain databases

Gene3Di3.40.50.1820. 1 hit.
InterProiIPR029058. AB_hydrolase.
IPR022742. Hydrolase_4.
[Graphical view]
PfamiPF12146. Hydrolase_4. 1 hit.
[Graphical view]
SUPFAMiSSF53474. SSF53474. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiABHDD_MOUSE
AccessioniPrimary (citable) accession number: Q80UX8
Secondary accession number(s): Q8BXS1, Q9D0V5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 20, 2007
Last sequence update: June 1, 2003
Last modified: November 2, 2016
This is version 106 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.