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Protein
Submitted name:

Phosphatidylinositol 3-kinase regulatory subunit alpha

Gene

Pik3r1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinaseImported, Transferase

Names & Taxonomyi

Protein namesi
Submitted name:
Phosphatidylinositol 3-kinase regulatory subunit alphaImported
Submitted name:
Phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (P85 alpha)Imported
Gene namesi
Name:Pik3r1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 13

Organism-specific databases

MGIiMGI:97583 Pik3r1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSMUSG00000041417

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

IntActiQ80UI5, 1 interactor

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini63 – 158SH2InterPro annotationAdd BLAST96
Domaini354 – 448SH2InterPro annotationAdd BLAST95

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili179 – 199Sequence analysisAdd BLAST21
Coiled coili258 – 292Sequence analysisAdd BLAST35

Keywords - Domaini

Coiled coilSequence analysis, SH2 domainPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG4637 Eukaryota
ENOG410XP6R LUCA
GeneTreeiENSGT00390000010431
HOGENOMiHOG000008438
HOVERGENiHBG082100

Family and domain databases

CDDicd09930 SH2_cSH2_p85_like, 1 hit
cd09942 SH2_nSH2_p85_like, 1 hit
Gene3Di3.30.505.10, 2 hits
InterProiView protein in InterPro
IPR032498 PI3K_P85_iSH2
IPR035020 PI3kinase_P85_cSH2
IPR035022 PI3kinase_P85_nSH2
IPR001720 PI3kinase_P85_p55
IPR000980 SH2
IPR036860 SH2_dom_sf
PANTHERiPTHR10155 PTHR10155, 1 hit
PfamiView protein in Pfam
PF16454 PI3K_P85_iSH2, 1 hit
PF00017 SH2, 2 hits
PRINTSiPR00401 SH2DOMAIN
SMARTiView protein in SMART
SM00252 SH2, 2 hits
SUPFAMiSSF55550 SSF55550, 2 hits
PROSITEiView protein in PROSITE
PS50001 SH2, 2 hits

Sequencei

Sequence statusi: Complete.

Q80UI5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYTTVWTMED LDLECAKTDI NCGTDLVFYI EMDPPALPPK PPKPTTVANN
60 70 80 90 100
SMNNNMSLQD AEWYWGDISR EEVNEKLRDT ADGTFLVRDA STKMHGDYTL
110 120 130 140 150
TLRKGGNNKL IKIFHRDGKY GFSDPLTFNS VVELINHYRN ESLAQYNPKL
160 170 180 190 200
DVKLLYPVSK YQQDQVVKED NIEAVGKKLH EYNTQFQEKS REYDRLYEEY
210 220 230 240 250
TRTSQEIQMK RTAIEAFNET IKIFEEQCQT QERYSKEYIE KFKREGNEKE
260 270 280 290 300
IQRIMHNHDK LKSRISEIID SRRRLEEDLK KQAAEYREID KRMNSIKPDL
310 320 330 340 350
IQLRKTRDQY LMWLTQKGVR QKKLNEWLGN ENTEDQYSLV EDDEDLPHHD
360 370 380 390 400
EKTWNVGSSN RNKAENLLRG KRDGTFLVRE SSKQGCYACS VVVDGEVKHC
410 420 430 440 450
VINKTATGYG FAEPYNLYSS LKELVLHYQH TSLVQHNDSL NVTLAYPVYA

QQRR
Length:454
Mass (Da):53,399
Last modified:June 1, 2003 - v1
Checksum:i543B736F6439FFFF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC107663 Genomic DNA No translation available.
AC153139 Genomic DNA No translation available.
BC051106 mRNA Translation: AAH51106.1
RefSeqiNP_001020126.1, NM_001024955.2
UniGeneiMm.259333

Genome annotation databases

EnsembliENSMUST00000035532; ENSMUSP00000047004; ENSMUSG00000041417
GeneIDi18708
UCSCiuc007rrs.3 mouse

Similar proteinsi

Entry informationi

Entry nameiQ80UI5_MOUSE
AccessioniPrimary (citable) accession number: Q80UI5
Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: June 1, 2003
Last modified: May 23, 2018
This is version 119 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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