Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q80U52 (Q80U52_MOUSE) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 66. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Sodium/hydrogen exchanger RuleBase RU003722
Gene names
Name:Slc9a6 MGI 2443511
Synonyms:mKIAA0267 EMBL BAC65514.1
OrganismMus musculus (Mouse) EMBL BAC65514.1
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Protein attributes

Sequence length700 AA.
Sequence statusFragment.
Protein existenceEvidence at transcript level

Ontologies

Keywords
   Biological processAntiport RuleBase RU003722
Ion transport
Sodium transport RuleBase RU003722
Transport
   Cellular componentMembrane
   DomainTransmembrane RuleBase RU003721
   LigandSodium
Gene Ontology (GO)
   Biological_processaxon extension

Inferred from sequence orthology PubMed 24035762. Source: MGI

brain-derived neurotrophic factor receptor signaling pathway

Inferred from mutant phenotype PubMed 24035762. Source: MGI

dendrite extension

Inferred from sequence orthology PubMed 24035762. Source: MGI

dendritic spine development

Inferred from mutant phenotype PubMed 24035762. Source: MGI

neuron projection morphogenesis

Inferred from sequence orthology PubMed 24035762. Source: MGI

proton transport

Inferred from mutant phenotype PubMed 24035762. Source: MGI

regulation of neurotrophin TRK receptor signaling pathway

Inferred from mutant phenotype PubMed 24035762. Source: MGI

regulation of pH

Inferred from electronic annotation. Source: InterPro

synapse organization

Inferred from mutant phenotype PubMed 24035762. Source: MGI

   Cellular_componentaxon terminus

Inferred from direct assay PubMed 23303939. Source: MGI

axonal spine

Inferred from direct assay PubMed 23303939. Source: MGI

cytoplasmic vesicle

Inferred from direct assay PubMed 23303939. Source: MGI

dendrite

Inferred from direct assay PubMed 23303939. Source: MGI

early endosome

Inferred from direct assay PubMed 24035762. Source: MGI

early endosome membrane

Inferred from electronic annotation. Source: Ensembl

endoplasmic reticulum membrane

Inferred from electronic annotation. Source: Ensembl

endosome

Inferred from direct assay PubMed 24035762. Source: MGI

integral component of membrane

Inferred from electronic annotation. Source: UniProtKB-KW

late endosome

Inferred from direct assay PubMed 24035762. Source: MGI

mitochondrion

Inferred from direct assay PubMed 14651853. Source: MGI

plasma membrane

Inferred from direct assay PubMed 23303939. Source: MGI

recycling endosome

Inferred from direct assay PubMed 23303939PubMed 24035762. Source: MGI

recycling endosome membrane

Inferred from electronic annotation. Source: Ensembl

synapse

Inferred from direct assay PubMed 24035762. Source: MGI

   Molecular_functionsodium:proton antiporter activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Experimental info

Non-terminal residue11 EMBL BAC65514.1

Sequences

Sequence LengthMass (Da)Tools
Q80U52 [UniParc].

Last modified June 1, 2003. Version 1.
Checksum: 5CA8EFCB0FD514FA

FASTA70077,751
        10         20         30         40         50         60 
GARRGWRLAP VRRGVCGPRA RPLMRPLWLL FAVSFFGWTG ALDGSGGTTR AMDEEIVSEK 

        70         80         90        100        110        120 
QAEESHRQDS ANLLIFILLL TLTILTIWLF KHRRARFLHE TGLAMIYGLL VGLVLRYGIH 

       130        140        150        160        170        180 
VPSDVNNVTL SCEVQSSPTT LLVNVSGKFY EYTLKGEISS HELNNVQDNE MLRKVTFDPE 

       190        200        210        220        230        240 
VFFNILLPPI IFYAGYSLKR RHFFRNLGSI LAYAFLGTAI SCFVIGSIMY GCVTLMKVTG 

       250        260        270        280        290        300 
QLAGDFYFTD CLLFGAIVSA TDPVTVLAIF HELQVDVELY ALLFGESVLN DAVAIVLSSS 

       310        320        330        340        350        360 
IVAYQPAGDN SHTFDVTAMF KSIGIFLGIF SGSFAMGAAT GVVTALVTKF TKLREFQLLE 

       370        380        390        400        410        420 
TGLFFLMSWS TFLLAEAWGF TGVVAVLFCG ITQAHYTYNN LSTESQHRTK QLFELLNFLA 

       430        440        450        460        470        480 
ENFIFSYMGL TLFTFQNHVF NPTFVVGAFI AIFLGRAANI YPLSLLLNLG RRSKIGSNFQ 

       490        500        510        520        530        540 
HMMMFAGLRG AMAFALAIRD TATYARQMMF STTLLIVFFT VWVFGGGTTA MLSCLHIRVG 

       550        560        570        580        590        600 
VDSDQEHLGV PDNERRTTKA ESAWLFRMWY NFDHNYLKPL LTHSGPPLTT TLPACCGPIA 

       610        620        630        640        650        660 
RCLTSPQAYE NQEQLKDDDS DLILNDGDIS LTYGDSTVNT ESATASAPRR FMGNSSEDAL 

       670        680        690        700 
DRELTFGDHE LVIRGTRLVL PMDDSEPALN SLDDTRHSPA 

« Hide

References

[1]"Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries."
Okazaki N., Kikuno R., Ohara R., Inamoto S., Aizawa H., Yuasa S., Nakajima D., Nagase T., Ohara O., Koga H.
DNA Res. 10:35-48(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Tissue: Brain EMBL BAC65514.1.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AK122232 mRNA. Translation: BAC65514.1.
UniGeneMm.17815.

3D structure databases

ProteinModelPortalQ80U52.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Organism-specific databases

MGIMGI:2443511. Slc9a6.

Phylogenomic databases

HOVERGENHBG055575.
InParanoidQ80U52.

Gene expression databases

BgeeQ80U52.
GenevestigatorQ80U52.

Family and domain databases

InterProIPR006153. Cation/H_exchanger.
IPR018422. Cation/H_exchanger_CPA1.
IPR002090. Na/H_exchanger_6.
IPR004709. NaH_exchanger.
[Graphical view]
PANTHERPTHR10110. PTHR10110. 1 hit.
PfamPF00999. Na_H_Exchanger. 1 hit.
[Graphical view]
PRINTSPR01084. NAHEXCHNGR.
PR01088. NAHEXCHNGR6.
TIGRFAMsTIGR00840. b_cpa1. 1 hit.
ProtoNetSearch...

Other

SOURCESearch...

Entry information

Entry nameQ80U52_MOUSE
AccessionPrimary (citable) accession number: Q80U52
Entry history
Integrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: June 1, 2003
Last modified: July 9, 2014
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)