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Q80U52

- Q80U52_MOUSE

UniProt

Q80U52 - Q80U52_MOUSE

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Protein

Sodium/hydrogen exchanger

Gene
Slc9a6, mKIAA0267
Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 5 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. sodium:proton antiporter activity Source: InterPro

GO - Biological processi

  1. axon extension Source: MGI
  2. brain-derived neurotrophic factor receptor signaling pathway Source: MGI
  3. dendrite extension Source: MGI
  4. dendritic spine development Source: MGI
  5. neuron projection morphogenesis Source: MGI
  6. proton transport Source: MGI
  7. regulation of neurotrophin TRK receptor signaling pathway Source: MGI
  8. regulation of pH Source: InterPro
  9. synapse organization Source: MGI
Complete GO annotation...

Keywords - Biological processi

AntiportUniRule annotation, Ion transport, Sodium transportUniRule annotation, Transport

Keywords - Ligandi

Sodium

Names & Taxonomyi

Protein namesi
Recommended name:
Sodium/hydrogen exchangerUniRule annotation
Gene namesi
Name:Slc9a6Imported
Synonyms:mKIAA0267Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:2443511. Slc9a6.

Subcellular locationi

GO - Cellular componenti

  1. axonal spine Source: MGI
  2. axon terminus Source: MGI
  3. cytoplasmic vesicle Source: MGI
  4. dendrite Source: MGI
  5. early endosome Source: MGI
  6. early endosome membrane Source: Ensembl
  7. endoplasmic reticulum membrane Source: Ensembl
  8. endosome Source: MGI
  9. integral component of membrane Source: UniProtKB-KW
  10. late endosome Source: MGI
  11. mitochondrion Source: MGI
  12. plasma membrane Source: MGI
  13. recycling endosome Source: MGI
  14. recycling endosome membrane Source: Ensembl
  15. synapse Source: MGI
Complete GO annotation...

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiQ80U52.
GenevestigatoriQ80U52.

Structurei

3D structure databases

ProteinModelPortaliQ80U52.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

TransmembraneUniRule annotation

Phylogenomic databases

HOVERGENiHBG055575.
InParanoidiQ80U52.

Family and domain databases

InterProiIPR006153. Cation/H_exchanger.
IPR018422. Cation/H_exchanger_CPA1.
IPR002090. Na/H_exchanger_6.
IPR004709. NaH_exchanger.
[Graphical view]
PANTHERiPTHR10110. PTHR10110. 1 hit.
PfamiPF00999. Na_H_Exchanger. 1 hit.
[Graphical view]
PRINTSiPR01084. NAHEXCHNGR.
PR01088. NAHEXCHNGR6.
TIGRFAMsiTIGR00840. b_cpa1. 1 hit.

Sequencei

Sequence statusi: Fragment.

Q80U52-1 [UniParc]FASTAAdd to Basket

« Hide

GARRGWRLAP VRRGVCGPRA RPLMRPLWLL FAVSFFGWTG ALDGSGGTTR    50
AMDEEIVSEK QAEESHRQDS ANLLIFILLL TLTILTIWLF KHRRARFLHE 100
TGLAMIYGLL VGLVLRYGIH VPSDVNNVTL SCEVQSSPTT LLVNVSGKFY 150
EYTLKGEISS HELNNVQDNE MLRKVTFDPE VFFNILLPPI IFYAGYSLKR 200
RHFFRNLGSI LAYAFLGTAI SCFVIGSIMY GCVTLMKVTG QLAGDFYFTD 250
CLLFGAIVSA TDPVTVLAIF HELQVDVELY ALLFGESVLN DAVAIVLSSS 300
IVAYQPAGDN SHTFDVTAMF KSIGIFLGIF SGSFAMGAAT GVVTALVTKF 350
TKLREFQLLE TGLFFLMSWS TFLLAEAWGF TGVVAVLFCG ITQAHYTYNN 400
LSTESQHRTK QLFELLNFLA ENFIFSYMGL TLFTFQNHVF NPTFVVGAFI 450
AIFLGRAANI YPLSLLLNLG RRSKIGSNFQ HMMMFAGLRG AMAFALAIRD 500
TATYARQMMF STTLLIVFFT VWVFGGGTTA MLSCLHIRVG VDSDQEHLGV 550
PDNERRTTKA ESAWLFRMWY NFDHNYLKPL LTHSGPPLTT TLPACCGPIA 600
RCLTSPQAYE NQEQLKDDDS DLILNDGDIS LTYGDSTVNT ESATASAPRR 650
FMGNSSEDAL DRELTFGDHE LVIRGTRLVL PMDDSEPALN SLDDTRHSPA 700
Length:700
Mass (Da):77,751
Last modified:June 1, 2003 - v1
Checksum:i5CA8EFCB0FD514FA
GO

Non-terminal residue

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK122232 mRNA. Translation: BAC65514.1.
UniGeneiMm.17815.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK122232 mRNA. Translation: BAC65514.1 .
UniGenei Mm.17815.

3D structure databases

ProteinModelPortali Q80U52.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

MGIi MGI:2443511. Slc9a6.

Phylogenomic databases

HOVERGENi HBG055575.
InParanoidi Q80U52.

Miscellaneous databases

SOURCEi Search...

Gene expression databases

Bgeei Q80U52.
Genevestigatori Q80U52.

Family and domain databases

InterProi IPR006153. Cation/H_exchanger.
IPR018422. Cation/H_exchanger_CPA1.
IPR002090. Na/H_exchanger_6.
IPR004709. NaH_exchanger.
[Graphical view ]
PANTHERi PTHR10110. PTHR10110. 1 hit.
Pfami PF00999. Na_H_Exchanger. 1 hit.
[Graphical view ]
PRINTSi PR01084. NAHEXCHNGR.
PR01088. NAHEXCHNGR6.
TIGRFAMsi TIGR00840. b_cpa1. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries."
    Okazaki N., Kikuno R., Ohara R., Inamoto S., Aizawa H., Yuasa S., Nakajima D., Nagase T., Ohara O., Koga H.
    DNA Res. 10:35-48(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: BrainImported.

Entry informationi

Entry nameiQ80U52_MOUSE
AccessioniPrimary (citable) accession number: Q80U52
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: June 1, 2003
Last modified: July 9, 2014
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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