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Q80TY9

- Q80TY9_MOUSE

UniProt

Q80TY9 - Q80TY9_MOUSE

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Protein
Submitted name:

Adenylate cyclase 3, isoform CRA_b

Gene

Adcy3

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. adenylate cyclase activity Source: MGI
  2. nucleotide binding Source: UniProtKB-KW

GO - Biological processi

  1. activation of adenylate cyclase activity Source: MGI
  2. cAMP biosynthetic process Source: MGI
  3. intracellular signal transduction Source: InterPro
  4. sensory perception of smell Source: MGI
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotation

Keywords - Ligandi

Nucleotide-bindingSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Adenylate cyclase 3, isoform CRA_bImported
Submitted name:
MKIAA0511 proteinImported
Gene namesi
Name:Adcy3Imported
Synonyms:mKIAA0511Imported
ORF Names:mCG_116984Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:99675. Adcy3.

Subcellular locationi

GO - Cellular componenti

  1. cilium Source: MGI
  2. cytoplasm Source: Ensembl
  3. plasma membrane Source: MGI
Complete GO annotation...

Expressioni

Gene expression databases

GenevestigatoriQ80TY9.

Family & Domainsi

Sequence similaritiesi

Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000006941.
HOVERGENiHBG050458.
KOiK08043.

Family and domain databases

Gene3Di3.30.70.1230. 2 hits.
InterProiIPR001054. A/G_cyclase.
IPR018297. A/G_cyclase_CS.
IPR029787. Nucleotide_cyclase.
[Graphical view]
PfamiPF00211. Guanylate_cyc. 2 hits.
[Graphical view]
SMARTiSM00044. CYCc. 2 hits.
[Graphical view]
SUPFAMiSSF55073. SSF55073. 2 hits.
PROSITEiPS00452. GUANYLATE_CYCLASE_1. 2 hits.
PS50125. GUANYLATE_CYCLASE_2. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q80TY9-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
KQPAANMPRN QGFSDPEYSA EYSAEYSVSL PSDPDRGVGR THEISVRNSG
60 70 80 90 100
SCLCLPRFMR LTFVPESLEN LYQTYFKRQR HETLLVLVVF AALFDCYVVV
110 120 130 140 150
MCAVVFSSDK LAPLMVAGFG LVLDIILFVL CKKGLLPDRV SRKVVPYLLW
160 170 180 190 200
LLISAQIFSY LGLNFSRAHA ASDTVGWQAF FVFSFFITLP LSLSPIVIIS
210 220 230 240 250
VVSCVVHTLV LGVTVAQQQQ DELEGMQLLR EILANVFLYL CAIIVGIMSY
260 270 280 290 300
YMADRKHRKA FLEARQSLEV KMNLEEQSQQ QENLMLSILP KHVADEMLKD
310 320 330 340 350
MKKDESQKDQ QQFNTMYMYR HENVSILFAD IVGFTQLSSA CSAQELVKLL
360 370 380 390 400
NELFARFDKL AAKYHQLRIK ILGDCYYCIC GLPDYREDHA VCSILMGLAM
410 420 430 440 450
VEAISYVREK TKTGVDMRVG VHTGTVLGGV LGQKRWQYDV WSTDVTVANK
460 470 480 490 500
MEAGGIPGRV HISQSTMDCL KGEFDVEPGD GGSRCDYLDE KGIETYLIIA
510 520 530 540 550
SKPEVKKTAQ NGLNGSAVPN GAPASSKPSS PALIETKEPN GSAHASGSTS
560 570 580 590 600
EEAEEQEAQA DNPSFPNPRR RLRLQDLADR VVDASEDEHE LNQLLNEALL
610 620 630 640 650
ERESAQVVKK RNTFLLTMRF MDPEMETRYS VEKEKQSGAA FSCSCVVLFC
660 670 680 690 700
TAMVEILIDP WLMTNYVTFV VGEVLLLILT ICSMAAIFPR SFPKKLVAFS
710 720 730 740 750
SWIDRTRWAR NTWAMLAIFI LVMANVVDML SCLQYYMGPY NMTAGMELDG
760 770 780 790 800
GCMENPKYYN YVAVLSLIAT IMLVQVSHMV KLTLMLLVTG AVTALNLYAW
810 820 830 840 850
CPVFDEYDHK RFQEKDSPMV ALEKMQVLAT PGLNGTDRLP LVPSKYSMTV
860 870 880 890 900
MMFVMMLSFY YFSRHVEKLA RTLFLWKIEV HDQKERVYEM RRWNEALVTN
910 920 930 940 950
MLPEHVARHF LGSKKRDEEL YSQSYDEIGV MFASLPNFAD FYTEESINNG
960 970 980 990 1000
GIECLRFLNE IISDFDSLLD NPKFRVITKI KTIGSTYMAA SGVTPDVNTN
1010 1020 1030 1040 1050
GFTSSSKEEK SDKERWQHLA DLADFALAMK DTLTNINNQS FNNFMLRIGM
1060 1070 1080 1090 1100
NKGGVLAGVI GARKPHYDIW GNTVNVASRM ESTGVMGNIQ VVEETQVILR
1110 1120 1130 1140 1150
EYGFRFVRRG PIFVKGKGEL LTFFLKGRDR PAAFPNGSSV TLPHQVVDNP
Length:1,150
Mass (Da):129,608
Last modified:June 1, 2003 - v1
Checksum:i734089FD1C0819B7
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK122298 mRNA. Translation: BAC65580.1.
CH466623 Genomic DNA. Translation: EDL01375.1.
CH466623 Genomic DNA. Translation: EDL01376.1.
RefSeqiNP_001153008.1. NM_001159536.1.
NP_001153009.1. NM_001159537.1.
NP_612178.2. NM_138305.3.
UniGeneiMm.489807.

Genome annotation databases

GeneIDi104111.
KEGGimmu:104111.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK122298 mRNA. Translation: BAC65580.1 .
CH466623 Genomic DNA. Translation: EDL01375.1 .
CH466623 Genomic DNA. Translation: EDL01376.1 .
RefSeqi NP_001153008.1. NM_001159536.1.
NP_001153009.1. NM_001159537.1.
NP_612178.2. NM_138305.3.
UniGenei Mm.489807.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 104111.
KEGGi mmu:104111.

Organism-specific databases

CTDi 109.
MGIi MGI:99675. Adcy3.

Phylogenomic databases

HOGENOMi HOG000006941.
HOVERGENi HBG050458.
KOi K08043.

Miscellaneous databases

ChiTaRSi Adcy3. mouse.
NextBioi 356544.
SOURCEi Search...

Gene expression databases

Genevestigatori Q80TY9.

Family and domain databases

Gene3Di 3.30.70.1230. 2 hits.
InterProi IPR001054. A/G_cyclase.
IPR018297. A/G_cyclase_CS.
IPR029787. Nucleotide_cyclase.
[Graphical view ]
Pfami PF00211. Guanylate_cyc. 2 hits.
[Graphical view ]
SMARTi SM00044. CYCc. 2 hits.
[Graphical view ]
SUPFAMi SSF55073. SSF55073. 2 hits.
PROSITEi PS00452. GUANYLATE_CYCLASE_1. 2 hits.
PS50125. GUANYLATE_CYCLASE_2. 2 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome."
    Mural R.J., Adams M.D., Myers E.W., Smith H.O., Miklos G.L., Wides R., Halpern A., Li P.W., Sutton G.G., Nadeau J., Salzberg S.L., Holt R.A., Kodira C.D., Lu F., Chen L., Deng Z., Evangelista C.C., Gan W.
    , Heiman T.J., Li J., Li Z., Merkulov G.V., Milshina N.V., Naik A.K., Qi R., Shue B.C., Wang A., Wang J., Wang X., Yan X., Ye J., Yooseph S., Zhao Q., Zheng L., Zhu S.C., Biddick K., Bolanos R., Delcher A.L., Dew I.M., Fasulo D., Flanigan M.J., Huson D.H., Kravitz S.A., Miller J.R., Mobarry C.M., Reinert K., Remington K.A., Zhang Q., Zheng X.H., Nusskern D.R., Lai Z., Lei Y., Zhong W., Yao A., Guan P., Ji R.R., Gu Z., Wang Z.Y., Zhong F., Xiao C., Chiang C.C., Yandell M., Wortman J.R., Amanatides P.G., Hladun S.L., Pratts E.C., Johnson J.E., Dodson K.L., Woodford K.J., Evans C.A., Gropman B., Rusch D.B., Venter E., Wang M., Smith T.J., Houck J.T., Tompkins D.E., Haynes C., Jacob D., Chin S.H., Allen D.R., Dahlke C.E., Sanders R., Li K., Liu X., Levitsky A.A., Majoros W.H., Chen Q., Xia A.C., Lopez J.R., Donnelly M.T., Newman M.H., Glodek A., Kraft C.L., Nodell M., Ali F., An H.J., Baldwin-Pitts D., Beeson K.Y., Cai S., Carnes M., Carver A., Caulk P.M., Center A., Chen Y.H., Cheng M.L., Coyne M.D., Crowder M., Danaher S., Davenport L.B., Desilets R., Dietz S.M., Doup L., Dullaghan P., Ferriera S., Fosler C.R., Gire H.C., Gluecksmann A., Gocayne J.D., Gray J., Hart B., Haynes J., Hoover J., Howland T., Ibegwam C., Jalali M., Johns D., Kline L., Ma D.S., MacCawley S., Magoon A., Mann F., May D., McIntosh T.C., Mehta S., Moy L., Moy M.C., Murphy B.J., Murphy S.D., Nelson K.A., Nuri Z., Parker K.A., Prudhomme A.C., Puri V.N., Qureshi H., Raley J.C., Reardon M.S., Regier M.A., Rogers Y.H., Romblad D.L., Schutz J., Scott J.L., Scott R., Sitter C.D., Smallwood M., Sprague A.C., Stewart E., Strong R.V., Suh E., Sylvester K., Thomas R., Tint N.N., Tsonis C., Wang G., Wang G., Williams M.S., Williams S.M., Windsor S.M., Wolfe K., Wu M.M., Zaveri J., Chaturvedi K., Gabrielian A.E., Ke Z., Sun J., Subramanian G., Venter J.C., Pfannkoch C.M., Barnstead M., Stephenson L.D.
    Science 296:1661-1671(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: MixedImported.
  2. "Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries."
    Okazaki N., Kikuno R., Ohara R., Inamoto S., Aizawa H., Yuasa S., Nakajima D., Nagase T., Ohara O., Koga H.
    DNA Res. 10:35-48(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: BrainImported.
  3. Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.
    Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: MixedImported.

Entry informationi

Entry nameiQ80TY9_MOUSE
AccessioniPrimary (citable) accession number: Q80TY9
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: June 1, 2003
Last modified: November 26, 2014
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)