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Protein

Synaptic vesicle membrane protein VAT-1 homolog-like

Gene

Vat1l

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Names & Taxonomyi

Protein namesi
Recommended name:
Synaptic vesicle membrane protein VAT-1 homolog-like (EC:1.-.-.-)
Gene namesi
Name:Vat1l
Synonyms:Kiaa1576
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 8

Organism-specific databases

MGIiMGI:2142534. Vat1l.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 417417Synaptic vesicle membrane protein VAT-1 homolog-likePRO_0000160923Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei390 – 3901PhosphoserineCombined sources
Modified residuei391 – 3911PhosphothreonineCombined sources
Modified residuei393 – 3931PhosphothreonineCombined sources
Modified residuei394 – 3941PhosphoserineCombined sources

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiQ80TB8.
PaxDbiQ80TB8.
PeptideAtlasiQ80TB8.
PRIDEiQ80TB8.

PTM databases

iPTMnetiQ80TB8.
PhosphoSiteiQ80TB8.

Expressioni

Gene expression databases

BgeeiENSMUSG00000046844.
ExpressionAtlasiQ80TB8. baseline and differential.
GenevisibleiQ80TB8. MM.

Interactioni

Protein-protein interaction databases

BioGridi234760. 1 interaction.
IntActiQ80TB8. 1 interaction.
STRINGi10090.ENSMUSP00000053431.

Structurei

3D structure databases

ProteinModelPortaliQ80TB8.
SMRiQ80TB8. Positions 37-382.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG1198. Eukaryota.
COG0604. LUCA.
GeneTreeiENSGT00550000074483.
HOGENOMiHOG000294681.
HOVERGENiHBG002466.
InParanoidiQ80TB8.
OMAiICFMQAG.
OrthoDBiEOG091G0EEJ.
PhylomeDBiQ80TB8.
TreeFamiTF314255.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
3.90.180.10. 1 hit.
InterProiIPR013154. ADH_N.
IPR002085. ADH_SF_Zn-type.
IPR011032. GroES-like.
IPR016040. NAD(P)-bd_dom.
IPR020843. PKS_ER.
IPR002364. Quin_OxRdtase/zeta-crystal_CS.
[Graphical view]
PANTHERiPTHR11695. PTHR11695. 2 hits.
PfamiPF08240. ADH_N. 1 hit.
[Graphical view]
SMARTiSM00829. PKS_ER. 1 hit.
[Graphical view]
SUPFAMiSSF50129. SSF50129. 1 hit.
SSF51735. SSF51735. 1 hit.
PROSITEiPS01162. QOR_ZETA_CRYSTAL. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q80TB8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKEGVEKAE ETEQMIEKET SKEPAEGGDG SHRLGDAQEM RAVVLAGFGG
60 70 80 90 100
LNKLRLSRKA MPEPQDGELK IRVKACGLNF IDLMVRQGNI DNPPKTPLVP
110 120 130 140 150
GFECSGIVEA LGDSVKGYEI GDRVMAFVNY NAWAEVVCTP VEFVYKIPDD
160 170 180 190 200
MSFSEAAAFP MNFVTAYTML FEIANLREGM SVLVHSAGGG VGQAVAQLCS
210 220 230 240 250
TVPNVTVFGT ASTFKHEAIK DSVTHLFDRN ADYVQEVKRI SAEGVDIVLD
260 270 280 290 300
CLCGDNTGKG LSLLKPLGTY ILYGSSNMVT GETKSFFSFA KSWWQVEKVN
310 320 330 340 350
PIKLYEENKV IAGFSLLNLL FKQGRSGLIR GVVEKLIGLY NQKKIKPVVD
360 370 380 390 400
SLWALEEVKE AMQRIHDRGN IGKLILDVEK TPTPLMANDS TETSEAGEEE
410
EDHEGDSENK ERMPFIQ
Length:417
Mass (Da):45,817
Last modified:September 27, 2004 - v2
Checksum:i604E25BDFC698CB2
GO

Sequence cautioni

The sequence BAC65809 differs from that shown. Reason: Erroneous initiation. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK122527 mRNA. Translation: BAC65809.1. Different initiation.
BC056927 mRNA. Translation: AAH56927.1.
CCDSiCCDS22689.1.
RefSeqiNP_766604.2. NM_173016.3.
UniGeneiMm.334825.

Genome annotation databases

EnsembliENSMUST00000049509; ENSMUSP00000053431; ENSMUSG00000046844.
GeneIDi270097.
KEGGimmu:270097.
UCSCiuc009noa.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK122527 mRNA. Translation: BAC65809.1. Different initiation.
BC056927 mRNA. Translation: AAH56927.1.
CCDSiCCDS22689.1.
RefSeqiNP_766604.2. NM_173016.3.
UniGeneiMm.334825.

3D structure databases

ProteinModelPortaliQ80TB8.
SMRiQ80TB8. Positions 37-382.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi234760. 1 interaction.
IntActiQ80TB8. 1 interaction.
STRINGi10090.ENSMUSP00000053431.

PTM databases

iPTMnetiQ80TB8.
PhosphoSiteiQ80TB8.

Proteomic databases

MaxQBiQ80TB8.
PaxDbiQ80TB8.
PeptideAtlasiQ80TB8.
PRIDEiQ80TB8.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000049509; ENSMUSP00000053431; ENSMUSG00000046844.
GeneIDi270097.
KEGGimmu:270097.
UCSCiuc009noa.1. mouse.

Organism-specific databases

CTDi57687.
MGIiMGI:2142534. Vat1l.
RougeiSearch...

Phylogenomic databases

eggNOGiKOG1198. Eukaryota.
COG0604. LUCA.
GeneTreeiENSGT00550000074483.
HOGENOMiHOG000294681.
HOVERGENiHBG002466.
InParanoidiQ80TB8.
OMAiICFMQAG.
OrthoDBiEOG091G0EEJ.
PhylomeDBiQ80TB8.
TreeFamiTF314255.

Miscellaneous databases

ChiTaRSiVat1l. mouse.
PROiQ80TB8.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000046844.
ExpressionAtlasiQ80TB8. baseline and differential.
GenevisibleiQ80TB8. MM.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
3.90.180.10. 1 hit.
InterProiIPR013154. ADH_N.
IPR002085. ADH_SF_Zn-type.
IPR011032. GroES-like.
IPR016040. NAD(P)-bd_dom.
IPR020843. PKS_ER.
IPR002364. Quin_OxRdtase/zeta-crystal_CS.
[Graphical view]
PANTHERiPTHR11695. PTHR11695. 2 hits.
PfamiPF08240. ADH_N. 1 hit.
[Graphical view]
SMARTiSM00829. PKS_ER. 1 hit.
[Graphical view]
SUPFAMiSSF50129. SSF50129. 1 hit.
SSF51735. SSF51735. 1 hit.
PROSITEiPS01162. QOR_ZETA_CRYSTAL. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiVAT1L_MOUSE
AccessioniPrimary (citable) accession number: Q80TB8
Secondary accession number(s): Q6PGM9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 27, 2004
Last sequence update: September 27, 2004
Last modified: September 7, 2016
This is version 102 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.