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Protein

Glia maturation factor gamma

Gene

Gmfg

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  • actin binding Source: InterPro
  • Arp2/3 complex binding Source: InterPro
  • growth factor activity Source: UniProtKB-KW
  • kinase regulator activity Source: RGD

GO - Biological processi

Keywordsi

Molecular functionGrowth factor

Names & Taxonomyi

Protein namesi
Recommended name:
Glia maturation factor gamma
Short name:
GMF-gamma
Gene namesi
Name:Gmfg
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Unplaced

Organism-specific databases

RGDi620506 Gmfg

Subcellular locationi

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedBy similarity
ChainiPRO_00002149492 – 142Glia maturation factor gammaAdd BLAST141

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei2N-acetylserineBy similarity1

Keywords - PTMi

Acetylation

Proteomic databases

PaxDbiQ80T18
PRIDEiQ80T18

PTM databases

iPTMnetiQ80T18
PhosphoSitePlusiQ80T18

Expressioni

Tissue specificityi

Expressed in rat thymus, testis, and spleen. Is present predominantly in proliferative and differentiative organs.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000026891

Structurei

3D structure databases

ProteinModelPortaliQ80T18
SMRiQ80T18
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini4 – 139ADF-HPROSITE-ProRule annotationAdd BLAST136

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG1736 Eukaryota
ENOG4111RK6 LUCA
HOGENOMiHOG000175654
HOVERGENiHBG003045
InParanoidiQ80T18
PhylomeDBiQ80T18

Family and domain databases

CDDicd11283 ADF_GMF-beta_like, 1 hit
Gene3Di3.40.20.10, 1 hit
InterProiView protein in InterPro
IPR002108 ADF-H
IPR029006 ADF-H/Gelsolin-like_dom_sf
IPR011171 GMF
IPR030076 GMFG
PANTHERiPTHR11249 PTHR11249, 1 hit
PTHR11249:SF4 PTHR11249:SF4, 1 hit
PfamiView protein in Pfam
PF00241 Cofilin_ADF, 1 hit
PIRSFiPIRSF001788 GMF-beta, 1 hit
SMARTiView protein in SMART
SM00102 ADF, 1 hit
PROSITEiView protein in PROSITE
PS51263 ADF_H, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q80T18-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSDSLVVCDV DPELKETLRK FRFRKETNNA AIIMKVDKDR QMVVLEDEFQ
60 70 80 90 100
NVSPEELKLE LPERQPRFVV YSYKYVHDDG RVSYPLCFIF SSPVGCKPEQ
110 120 130 140
QMMYAGSKNR LVQIAELTKV FEIRTTDDLN ETWLKEKLAF FR
Length:142
Mass (Da):16,779
Last modified:June 1, 2003 - v1
Checksum:iB5468FC5F2EFFA05
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB007364 mRNA Translation: BAC76430.1
RefSeqiNP_851605.1, NM_181091.2
UniGeneiRn.15333

Genome annotation databases

GeneIDi113940
KEGGirno:113940

Similar proteinsi

Entry informationi

Entry nameiGMFG_RAT
AccessioniPrimary (citable) accession number: Q80T18
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 26, 2004
Last sequence update: June 1, 2003
Last modified: May 23, 2018
This is version 84 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health