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Protein
Submitted name:

NOD2

Gene

Nod2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandATP-bindingSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
NOD2Imported
Submitted name:
Nucleotide-binding oligomerization domain-containing protein 2Imported
Gene namesi
Name:Nod2Imported
Synonyms:Card15Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 8

Organism-specific databases

MGIiMGI:2429397 Nod2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSMUSG00000055994

Interactioni

GO - Molecular functioni

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 82CARDInterPro annotationAdd BLAST82
Domaini107 – 178CARDInterPro annotationAdd BLAST72
Domaini266 – 402NACHTInterPro annotationAdd BLAST137

Keywords - Domaini

RepeatSAAS annotation

Phylogenomic databases

eggNOGiKOG4308 Eukaryota
ENOG410ZBX3 LUCA
GeneTreeiENSGT00860000133673
HOVERGENiHBG050792
KOiK10165

Family and domain databases

Gene3Di3.80.10.10, 1 hit
InterProiView protein in InterPro
IPR001315 CARD
IPR011029 DEATH-like_dom_sf
IPR018228 DNase_TatD-rel_CS
IPR001611 Leu-rich_rpt
IPR032675 LRR_dom_sf
IPR007111 NACHT_NTPase
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF00619 CARD, 1 hit
PF13516 LRR_6, 5 hits
SUPFAMiSSF47986 SSF47986, 2 hits
SSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS50209 CARD, 2 hits
PS50837 NACHT, 1 hit
PS01137 TATD_1, 1 hit

Sequencei

Sequence statusi: Complete.

Q80SY9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MCSQEEFQAQ RSQLVALLIS GSLEGFESIL DWLLSWDVLS REDYEGLSLP
60 70 80 90 100
GQPLSHSARR LLDTVWNKGV WGCQKLLEAV QEAQANSHTF ELYGSWDTHS
110 120 130 140 150
LHPTRDLQSH RPAIVRRLYN HVEAMLELAR EGGFLSQYEC EEIRLPIFTS
160 170 180 190 200
SQRARRLLDL AAVKANGLAA FLLQHVRELP APLPLPYEAA ECQKFISKLR
210 220 230 240 250
TMVLTQSRFL STYDGSENLC LEDIYTENIL ELQTEVGTAG ALQKSPAILG
260 270 280 290 300
LEDLFDTHGH LNRDADTILV VGEAGSGKST LLQRLHLLWA TGRSFQEFLF
310 320 330 340 350
IFPFSCRQLQ CVAKPLSLRT LLFEHCCWPD VAQDDVFQFL LDHPDRVLLT
360 370 380 390 400
FDGLDEFKFR FTDRERHCSP IDPTSVQTLL FNLLQGNLLK NACKVLTSRP
410 420 430 440 450
DAVSALLRKF VRTELQLKGF SEEGIQLYLR KHHREPGVAD RLIQLIQATS
460 470 480 490 500
ALHGLCHLPV FSWMVSRCHR ELLLQNRGFP TTSTDMYLLI LQHFLLHASP
510 520 530 540 550
PDSSPLGLGP GLLQSRLSTL LHLGHLALRG LAMSCYVFSA QQLQAAQVDS
560 570 580 590 600
DDISLGFLVR AQSSVPGSKA PLEFLHITFQ CFFAAFYLAV SADTSVASLK
610 620 630 640 650
HLFSCGRLGS SLLGRLLPNL CIQGSRVKKG SEAALLQKAE PHNLQITAAF
660 670 680 690 700
LAGLLSQQHR DLLAACQVSE RVLLQRQARA RSCLAHSLRE HFHSIPPAVP
710 720 730 740 750
GETKSMHAMP GFIWLIRSLY EMQEEQLAQE AVRRLDIGHL KLTFCRVGPA
760 770 780 790 800
ECAALAFVLQ HLQRPVALQL DYNSVGDVGV EQLRPCLGVC TALYLRDNNI
810 820 830 840 850
SDRGARTLVE CALRCEQLQK LALFNNKLTD ACACSMAKLL AHKQNFLSLR
860 870 880 890 900
VGNNHITAAG AEVLAQGLKS NTSLKFLGFW GNSVGDKGTQ ALAEVVADHQ
910 920 930 940 950
NLKWLSLVGN NIGSMGAEAL ALMLEKNKSL EELCLEENHI CDEGVYSLAE
960 970 980 990 1000
GLKRNSTLKF LKLSNNGITY RGAEALLQAL SRNSAILEVW LRGNTFSLEE
1010
IQTLSSRDAR LLL
Length:1,013
Mass (Da):112,779
Last modified:June 1, 2003 - v1
Checksum:i459CD3CBE6F66375
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC156937 Genomic DNA No translation available.
AY160220 mRNA Translation: AAN52477.1
AH012069
, AY160340, AY160341, AY160342, AY160343, AY160344, AY160345, AY160346, AY160347 Genomic DNA Translation: AAN57787.1
AH012071
, AY160360, AY160361, AY160363, AY160364, AY160365, AY160366, AY160367 Genomic DNA Translation: AAN57789.1
AH012114
, AY160561, AY160562, AY160563, AY160564, AY160565, AY160566, AY160567 Genomic DNA Translation: AAN62470.1
AH012115
, AY160570, AY160571, AY160572, AY160573, AY160574, AY160575, AY160576, AY160577 Genomic DNA Translation: AAN62471.1
AH012151
, AY160600, AY160601, AY160602, AY160603, AY160604, AY160605, AY160607 Genomic DNA Translation: AAN63034.1
AH012152
, AY160610, AY160612, AY160613, AY160614, AY160615, AY160616, AY160617 Genomic DNA Translation: AAN63035.1
AH012156
, AY160650, AY160651, AY160652, AY160653, AY160654, AY160655, AY160656, AY160657 Genomic DNA Translation: AAN63039.1
RefSeqiNP_665856.2, NM_145857.2
UniGeneiMm.222633

Genome annotation databases

EnsembliENSMUST00000118370; ENSMUSP00000113773; ENSMUSG00000055994
GeneIDi257632
KEGGimmu:257632

Similar proteinsi

Entry informationi

Entry nameiQ80SY9_MOUSE
AccessioniPrimary (citable) accession number: Q80SY9
Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: June 1, 2003
Last modified: May 23, 2018
This is version 136 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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